JP5557982B2 - 天然ＩｇＭ抗体およびその阻害剤 - Google Patents

天然ＩｇＭ抗体およびその阻害剤 Download PDF

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Publication number
JP5557982B2
JP5557982B2 JP2007501869A JP2007501869A JP5557982B2 JP 5557982 B2 JP5557982 B2 JP 5557982B2 JP 2007501869 A JP2007501869 A JP 2007501869A JP 2007501869 A JP2007501869 A JP 2007501869A JP 5557982 B2 JP5557982 B2 JP 5557982B2
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Japan
Prior art keywords
peptide
igm
antibody
seq
cells
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Expired - Fee Related
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JP2007501869A
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English (en)
Japanese (ja)
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JP2008504807A (ja
Inventor
マイケル シー． キャロル
ジュニア フランシス ディー． ムーア
ハーバート ビー． ヘクトマン
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Brigham and Womens Hospital Inc
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Brigham and Womens Hospital Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2007501869A 2004-03-01 2005-03-01 天然ＩｇＭ抗体およびその阻害剤 Expired - Fee Related JP5557982B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US54912304P 2004-03-01 2004-03-01
US60/549,123 2004-03-01
US58864804P 2004-07-16 2004-07-16
US60/588,648 2004-07-16
PCT/US2005/006276 WO2005085288A2 (en) 2004-03-01 2005-03-01 Natural igm antibodies and inhibitors thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011019668A Division JP5618852B2 (ja) 2004-03-01 2011-02-01 天然ＩｇＭ抗体およびその阻害剤

Publications (2)

Publication Number Publication Date
JP2008504807A JP2008504807A (ja) 2008-02-21
JP5557982B2 true JP5557982B2 (ja) 2014-07-23

Family

ID=34922704

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2007501869A Expired - Fee Related JP5557982B2 (ja) 2004-03-01 2005-03-01 天然ＩｇＭ抗体およびその阻害剤
JP2011019668A Expired - Fee Related JP5618852B2 (ja) 2004-03-01 2011-02-01 天然ＩｇＭ抗体およびその阻害剤
JP2014089965A Pending JP2014155497A (ja) 2004-03-01 2014-04-24 天然ＩｇＭ抗体およびその阻害剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2011019668A Expired - Fee Related JP5618852B2 (ja) 2004-03-01 2011-02-01 天然ＩｇＭ抗体およびその阻害剤
JP2014089965A Pending JP2014155497A (ja) 2004-03-01 2014-04-24 天然ＩｇＭ抗体およびその阻害剤

Country Status (9)

Country Link
US (5) US7442783B2 (enExample)
EP (2) EP2290077B1 (enExample)
JP (3) JP5557982B2 (enExample)
AT (1) ATE498010T1 (enExample)
AU (1) AU2005219839B9 (enExample)
CA (1) CA2560066A1 (enExample)
DE (1) DE602005026260D1 (enExample)
IL (1) IL177825A (enExample)
WO (1) WO2005085288A2 (enExample)

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US20100136684A1 (en) * 2004-03-01 2010-06-03 Carroll Michael C Natural IgM Antibodies
ATE498010T1 (de) 2004-03-01 2011-02-15 Immune Disease Inst Inc Natürliche igm-antikörper und inhibitoren davon
WO2011071883A1 (en) 2009-12-07 2011-06-16 Decimmune Therapeutics, Inc. Anti-inflammatory antibodies and uses therefor
CN103221062A (zh) * 2010-06-03 2013-07-24 阿布拉西斯生物科学有限责任公司 外周血sparc 结合抗体及其用途
WO2014055392A2 (en) * 2012-10-01 2014-04-10 Decimmune Therapeutics, Inc. Method of protecting cardiac function
US9409977B2 (en) 2013-03-12 2016-08-09 Decimmune Therapeutics, Inc. Humanized, anti-N2 antibodies
JP6551825B2 (ja) * 2014-02-10 2019-07-31 公立大学法人首都大学東京 クロマチン構造制御剤

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Also Published As

Publication number Publication date
US20140127214A1 (en) 2014-05-08
JP5618852B2 (ja) 2014-11-05
IL177825A (en) 2013-02-28
JP2008504807A (ja) 2008-02-21
US9914751B2 (en) 2018-03-13
US20050276811A1 (en) 2005-12-15
US20160280740A1 (en) 2016-09-29
AU2005219839B9 (en) 2011-12-22
EP2290077A2 (en) 2011-03-02
EP2290077B1 (en) 2016-01-27
US20170342109A1 (en) 2017-11-30
US7442783B2 (en) 2008-10-28
JP2014155497A (ja) 2014-08-28
JP2011139704A (ja) 2011-07-21
IL177825A0 (en) 2006-12-31
DE602005026260D1 (de) 2011-03-24
WO2005085288A2 (en) 2005-09-15
US20090176966A1 (en) 2009-07-09
US9657060B2 (en) 2017-05-23
AU2005219839A1 (en) 2005-09-15
CA2560066A1 (en) 2005-09-15
EP1725659B1 (en) 2011-02-09
HK1154904A1 (en) 2012-05-04
ATE498010T1 (de) 2011-02-15
AU2005219839B2 (en) 2011-11-24
EP1725659A2 (en) 2006-11-29
EP2290077A3 (en) 2011-05-18
WO2005085288A3 (en) 2006-08-03

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