JP5548842B2 - 新規なヘテロアリール置換ベンゾオキサゾール - Google Patents

新規なヘテロアリール置換ベンゾオキサゾール Download PDF

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Publication number
JP5548842B2
JP5548842B2 JP2009516443A JP2009516443A JP5548842B2 JP 5548842 B2 JP5548842 B2 JP 5548842B2 JP 2009516443 A JP2009516443 A JP 2009516443A JP 2009516443 A JP2009516443 A JP 2009516443A JP 5548842 B2 JP5548842 B2 JP 5548842B2
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alkyl
fluoroalkyl
nhc
methoxy
benzoxazol
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JP2009516443A
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Japanese (ja)
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JP2009541309A (ja
JP2009541309A5 (enExample
Inventor
ヨーナス・マルムストレム
ダーヴィド・ピリング
カン・スリヴォ
ダニエル・ソーン
ブリット−マーリー・スワーン
ダーヴィド・ウェンスブー
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ナヴィディア バイオファーマシューティカルズ インコーポレーテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2009516443A 2006-06-19 2007-06-18 新規なヘテロアリール置換ベンゾオキサゾール Expired - Fee Related JP5548842B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81493606P 2006-06-19 2006-06-19
US60/814,936 2006-06-19
PCT/SE2007/000591 WO2007149030A1 (en) 2006-06-19 2007-06-18 Novel heteroaryl substituted benzoxazoles

Publications (3)

Publication Number Publication Date
JP2009541309A JP2009541309A (ja) 2009-11-26
JP2009541309A5 JP2009541309A5 (enExample) 2010-08-05
JP5548842B2 true JP5548842B2 (ja) 2014-07-16

Family

ID=38833677

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009516443A Expired - Fee Related JP5548842B2 (ja) 2006-06-19 2007-06-18 新規なヘテロアリール置換ベンゾオキサゾール

Country Status (16)

Country Link
US (1) US7670591B2 (enExample)
EP (1) EP2035418A1 (enExample)
JP (1) JP5548842B2 (enExample)
KR (1) KR20090021224A (enExample)
CN (1) CN101506201B (enExample)
AR (1) AR061515A1 (enExample)
AU (1) AU2007261786A1 (enExample)
CA (1) CA2655084A1 (enExample)
CL (1) CL2007001784A1 (enExample)
IL (1) IL195669A0 (enExample)
MX (1) MX2008015718A (enExample)
NO (1) NO20090201L (enExample)
TW (1) TW200813035A (enExample)
UY (1) UY30419A1 (enExample)
WO (1) WO2007149030A1 (enExample)
ZA (1) ZA200810163B (enExample)

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TW200901998A (en) 2007-03-06 2009-01-16 Astrazeneca Ab Novel 2-heteroaryl substituted benzothiophenes and benzofuranes
JP2011524864A (ja) * 2008-05-30 2011-09-08 メルク・シャープ・エンド・ドーム・コーポレイション 新規な置換されたアザベンゾオキサゾール
US20110212031A1 (en) * 2008-10-31 2011-09-01 Cyrille Sur Novel substituted azabenzoxazoles
US8779149B2 (en) 2010-08-23 2014-07-15 Syntrix Biosystems, Inc. Aminopyridine- and aminopyrimidinecarboxamides as CXCR2 modulators
JP5937102B2 (ja) * 2010-12-14 2016-06-22 エレクトロフォレティクス リミテッド カゼインキナーゼ１デルタ（ｃｋ１デルタ）阻害剤
WO2014132919A1 (ja) * 2013-02-28 2014-09-04 国立大学法人京都大学 診断用組成物
KR101499329B1 (ko) * 2013-06-17 2015-03-06 주식회사 대웅제약 (2-(3,4-다이메톡시페닐)-5-(3-메톡시프로필)벤조퓨란)의결정형 및 이의 제조방법
JP6149684B2 (ja) * 2013-10-21 2017-06-21 ブラザー工業株式会社 携帯端末、画像処理装置、及びプログラム
WO2015112048A1 (en) * 2014-01-24 2015-07-30 Huawei Technologies Co., Ltd. Method and device for cross-polarization interference suppression
CN104059028B (zh) * 2014-06-06 2020-10-16 北京智博高科生物技术有限公司 与Aβ斑块具有亲和力的含手性侧链取代的氟代2-芳基苯并杂环化合物、其制备方法及应用
KR101709731B1 (ko) * 2015-05-22 2017-02-23 한국과학기술연구원 벤조옥사졸 또는 벤조티아졸 화합물, 그의 제조, 및 용도
US10324943B2 (en) * 2015-08-10 2019-06-18 Business Objects Software, Ltd. Auto-monitoring and adjustment of dynamic data visualizations
WO2017031239A1 (en) * 2015-08-18 2017-02-23 The Regents Of The University Of California Nitroxide containing amyloid binding agents for imaging and therapeutic uses
KR101812424B1 (ko) * 2016-12-28 2017-12-27 충북대학교 산학협력단 2-(2-아미노-5-(1-(피퍼리딘-4-일)-1H-피라졸-3-일)피리딘-3-일)벤조[d]옥사졸-6-올 및 이를 유효성분으로 포함하는 치매의 예방 및 치료용 조성물
EP4097092A1 (en) * 2020-01-28 2022-12-07 Protego Biopharma, Inc. Compounds, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding

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Also Published As

Publication number Publication date
AR061515A1 (es) 2008-09-03
CN101506201B (zh) 2012-03-14
UY30419A1 (es) 2008-01-31
TW200813035A (en) 2008-03-16
JP2009541309A (ja) 2009-11-26
AU2007261786A1 (en) 2007-12-27
NO20090201L (no) 2009-01-13
IL195669A0 (en) 2009-09-01
MX2008015718A (es) 2008-12-19
CA2655084A1 (en) 2007-12-27
EP2035418A1 (en) 2009-03-18
US7670591B2 (en) 2010-03-02
CN101506201A (zh) 2009-08-12
KR20090021224A (ko) 2009-02-27
CL2007001784A1 (es) 2008-01-18
WO2007149030A8 (en) 2008-02-28
ZA200810163B (en) 2010-05-26
WO2007149030A1 (en) 2007-12-27
US20080027051A1 (en) 2008-01-31

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