JP5543956B2 - 癌の処置のための方法および組成物 - Google Patents

癌の処置のための方法および組成物 Download PDF

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Publication number
JP5543956B2
JP5543956B2 JP2011501983A JP2011501983A JP5543956B2 JP 5543956 B2 JP5543956 B2 JP 5543956B2 JP 2011501983 A JP2011501983 A JP 2011501983A JP 2011501983 A JP2011501983 A JP 2011501983A JP 5543956 B2 JP5543956 B2 JP 5543956B2
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JP
Japan
Prior art keywords
cisplatin
treatment
cancer
arsenic
sodium meta
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2011501983A
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English (en)
Japanese (ja)
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JP2011515481A (ja
JP2011515481A5 (https=
Inventor
アンジェリカ バーガー,
ハンス ヘンドリクス,
ベルナルダス ラデマーカー,
Original Assignee
コミノックス・インコーポレイテッド
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Publication of JP2011515481A5 publication Critical patent/JP2011515481A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/36Arsenic; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2011501983A 2008-03-27 2009-03-24 癌の処置のための方法および組成物 Expired - Fee Related JP5543956B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3998708P 2008-03-27 2008-03-27
US61/039,987 2008-03-27
US12/408,864 US20090246291A1 (en) 2008-03-27 2009-03-23 Method and compositions for treatment of cancer
US12/408,864 2009-03-23
PCT/US2009/038104 WO2009120697A2 (en) 2008-03-27 2009-03-24 Method and compositions for treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014046212A Division JP2014101387A (ja) 2008-03-27 2014-03-10 癌の処置のための方法および組成物

Publications (3)

Publication Number Publication Date
JP2011515481A JP2011515481A (ja) 2011-05-19
JP2011515481A5 JP2011515481A5 (https=) 2012-04-05
JP5543956B2 true JP5543956B2 (ja) 2014-07-09

Family

ID=41114644

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011501983A Expired - Fee Related JP5543956B2 (ja) 2008-03-27 2009-03-24 癌の処置のための方法および組成物
JP2014046212A Withdrawn JP2014101387A (ja) 2008-03-27 2014-03-10 癌の処置のための方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014046212A Withdrawn JP2014101387A (ja) 2008-03-27 2014-03-10 癌の処置のための方法および組成物

Country Status (20)

Country Link
US (2) US20090246291A1 (https=)
EP (1) EP2268292B1 (https=)
JP (2) JP5543956B2 (https=)
KR (1) KR101634138B1 (https=)
CN (2) CN102046187A (https=)
AU (1) AU2009228378B2 (https=)
BR (1) BRPI0909164A2 (https=)
CA (1) CA2719766C (https=)
CY (1) CY1120536T1 (https=)
DK (1) DK2268292T3 (https=)
ES (1) ES2656762T3 (https=)
HU (1) HUE036609T2 (https=)
LT (1) LT2268292T (https=)
MX (1) MX2010010621A (https=)
PL (1) PL2268292T3 (https=)
PT (1) PT2268292T (https=)
RU (1) RU2508116C2 (https=)
SI (1) SI2268292T1 (https=)
WO (1) WO2009120697A2 (https=)
ZA (1) ZA201006988B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013504587A (ja) * 2009-09-10 2013-02-07 コミノックス・インコーポレイテッド 癌幹細胞を標的とした薬剤耐性癌治療法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1721615A1 (en) * 2005-05-09 2006-11-15 Komipharm International Co., Ltd. Pharmaceutical compositions comprising sodium or potassium arsenite for the treatment of urogenital cancer and its metastasis
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US8795738B2 (en) * 2009-11-12 2014-08-05 Board Of Regents Of The University Of Texas System Use of arsenic for cancer therapy protection
US11084811B2 (en) 2010-03-01 2021-08-10 Oncternal Therapeutics, Inc. Compounds for treatment of cancer
WO2012012305A2 (en) * 2010-07-18 2012-01-26 Niiki Pharma Inc. Combination therapy using a ruthenium complex
JP5997156B2 (ja) * 2010-08-24 2016-09-28 ジーティーエックス・インコーポレイテッド 癌の治療のための化合物
US20120251628A1 (en) * 2011-03-30 2012-10-04 Young Joo Min Compositions and methods for treatment of cancer
CA2835631A1 (en) * 2011-05-12 2012-11-15 Board Of Regents, The University Of Texas System Use of arsenic for cancer therapy protection
US8834938B2 (en) 2011-05-18 2014-09-16 Board Of Regents Of The University Of Texas System Use of arsenic for cancer therapy protection
US20160184356A1 (en) * 2013-03-15 2016-06-30 Ke Jian Jim Liu Arsenic-based treatment of cancers and inflammatory disorders
KR101309844B1 (ko) 2013-03-15 2013-09-23 박상채 항암 활성 증진용 한약재 및 이의 제조방법
MX372671B (es) * 2013-07-19 2020-04-23 Onyx Therapeutics Inc Inhibidores de proteasoma de epoxicetona peptídica en combinacion con inhibidores de cinasa pim para el tratamiento de canceres.
CA3041357A1 (en) * 2016-12-01 2018-06-07 Eupharma Pty Ltd Diarsenic tetraoxide compositions and their use in the treatment of cancers
KR102868121B1 (ko) * 2018-03-22 2025-10-14 코미팜 인터내셔널 오스트레일리아 피티와이 엘티디 메타 아비산염을 포함하는 약학 조성물 및 제조 방법
CN116236505A (zh) * 2023-03-15 2023-06-09 上海市第四人民医院 三氧化二砷在制备肺神经内分泌癌治疗药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6875451B2 (en) * 1997-10-15 2005-04-05 Polarx Biopharmaceuticals Inc. Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
TR200002243T2 (tr) * 1997-11-10 2000-12-21 Memorial Sloan-Kettering Cancer Center Arsenik trioksitin hazırlanması için işlem ve bunların kanser tedavisi için kullanımı.
KR20020083678A (ko) * 2001-04-28 2002-11-04 주식회사 한국미생물연구소 아르세닉산나트륨 염, 소디움 메타아르세나이트 또는 이의혼합물을 함유한 항암제 조성물
WO2003086424A1 (en) * 2002-04-10 2003-10-23 Korea Microbiological Laboratories, Ltd. Pharmaceutical composition comprising arsenite for the treatment of malignancy
EP1721615A1 (en) * 2005-05-09 2006-11-15 Komipharm International Co., Ltd. Pharmaceutical compositions comprising sodium or potassium arsenite for the treatment of urogenital cancer and its metastasis
US8097237B2 (en) * 2005-08-23 2012-01-17 Stc.Unm Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma
US7867492B2 (en) * 2007-10-12 2011-01-11 The John Hopkins University Compounds for hedgehog pathway blockade in proliferative disorders, including hematopoietic malignancies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013504587A (ja) * 2009-09-10 2013-02-07 コミノックス・インコーポレイテッド 癌幹細胞を標的とした薬剤耐性癌治療法

Also Published As

Publication number Publication date
SI2268292T1 (en) 2018-03-30
PT2268292T (pt) 2018-02-19
EP2268292B1 (en) 2017-12-27
AU2009228378A1 (en) 2009-10-01
CA2719766C (en) 2017-10-31
BRPI0909164A2 (pt) 2016-06-21
CN102046187A (zh) 2011-05-04
PL2268292T3 (pl) 2018-06-29
CA2719766A1 (en) 2009-10-01
WO2009120697A3 (en) 2010-02-18
ES2656762T3 (es) 2018-02-28
EP2268292A2 (en) 2011-01-05
WO2009120697A2 (en) 2009-10-01
ZA201006988B (en) 2012-05-30
EP2268292A4 (en) 2011-05-11
US20090246291A1 (en) 2009-10-01
WO2009120697A4 (en) 2010-04-15
CY1120536T1 (el) 2019-07-10
LT2268292T (lt) 2018-03-26
CN104997808A (zh) 2015-10-28
MX2010010621A (es) 2011-04-05
JP2014101387A (ja) 2014-06-05
JP2011515481A (ja) 2011-05-19
KR101634138B1 (ko) 2016-06-28
DK2268292T3 (en) 2018-03-12
HUE036609T2 (hu) 2018-07-30
KR20110009664A (ko) 2011-01-28
AU2009228378B2 (en) 2014-07-17
US20180055812A1 (en) 2018-03-01
RU2508116C2 (ru) 2014-02-27
RU2010143893A (ru) 2012-05-10

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