JP5538359B2 - リポソームボツリヌス毒素を使用する膀胱機能障害の治療 - Google Patents

リポソームボツリヌス毒素を使用する膀胱機能障害の治療 Download PDF

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Publication number
JP5538359B2
JP5538359B2 JP2011503214A JP2011503214A JP5538359B2 JP 5538359 B2 JP5538359 B2 JP 5538359B2 JP 2011503214 A JP2011503214 A JP 2011503214A JP 2011503214 A JP2011503214 A JP 2011503214A JP 5538359 B2 JP5538359 B2 JP 5538359B2
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Prior art keywords
bont
bladder
botulinum toxin
formulation
lipid
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JP2011503214A
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Japanese (ja)
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JP2011516497A (ja
JP2011516497A5 (cg-RX-API-DMAC7.html
Inventor
マイケル ビー. チャンセラー,
ジョナサン エイチ. カーフマン,
Original Assignee
リペラ ファーマシューティカルズ, インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2011503214A 2008-04-04 2009-04-03 リポソームボツリヌス毒素を使用する膀胱機能障害の治療 Expired - Fee Related JP5538359B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4253608P 2008-04-04 2008-04-04
US61/042,536 2008-04-04
US11026608P 2008-10-31 2008-10-31
US61/110,266 2008-10-31
PCT/US2009/039489 WO2009139984A2 (en) 2008-04-04 2009-04-03 Method of treatment for bladder dysfunction

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014000235A Division JP2014062125A (ja) 2008-04-04 2014-01-06 リポソームボツリヌス毒素を使用する膀胱機能障害の治療

Publications (3)

Publication Number Publication Date
JP2011516497A JP2011516497A (ja) 2011-05-26
JP2011516497A5 JP2011516497A5 (cg-RX-API-DMAC7.html) 2011-12-08
JP5538359B2 true JP5538359B2 (ja) 2014-07-02

Family

ID=41319235

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011503214A Expired - Fee Related JP5538359B2 (ja) 2008-04-04 2009-04-03 リポソームボツリヌス毒素を使用する膀胱機能障害の治療
JP2014000235A Withdrawn JP2014062125A (ja) 2008-04-04 2014-01-06 リポソームボツリヌス毒素を使用する膀胱機能障害の治療

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014000235A Withdrawn JP2014062125A (ja) 2008-04-04 2014-01-06 リポソームボツリヌス毒素を使用する膀胱機能障害の治療

Country Status (10)

Country Link
US (1) US20120093920A1 (cg-RX-API-DMAC7.html)
EP (2) EP2599476A1 (cg-RX-API-DMAC7.html)
JP (2) JP5538359B2 (cg-RX-API-DMAC7.html)
KR (1) KR20100131471A (cg-RX-API-DMAC7.html)
CN (1) CN102065841A (cg-RX-API-DMAC7.html)
AU (1) AU2009246834B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0911098A2 (cg-RX-API-DMAC7.html)
CA (1) CA2720523C (cg-RX-API-DMAC7.html)
MX (1) MX2010010635A (cg-RX-API-DMAC7.html)
WO (1) WO2009139984A2 (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2660901T3 (es) 2012-04-13 2018-03-26 Lubrizol Advanced Materials, Inc. Compuestos que inhiben la exocitosis neuronal (II)
EP2649985A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis (III)
EP2649983A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis (II)
EP2649984A1 (en) 2012-04-13 2013-10-16 Lipotec, S.A. Compounds which inhibit neuronal exocytosis
BR112015004110A2 (pt) 2012-08-31 2017-07-04 Taris Biomedical Llc sistemas e métodos de distribuição de drogas para tratamento de próstata
SI2890384T1 (sl) 2012-08-31 2022-02-28 Taris Biomedical Llc Sistemi za dostavo zdravila in postopki za zdravljenje raka sečnega mehurja, ki obsegajo oksaliplatin
EP3060197B1 (en) 2013-10-22 2023-06-07 Lipella Pharmaceuticals Inc. Delivery of agents using metastable liposomes
US20150250717A1 (en) 2014-03-06 2015-09-10 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder cancer with gemcitabine
US20160045623A1 (en) 2015-04-03 2016-02-18 Lipella Pharmaceuticals, Inc. Systems and Methods to Image Intercellular and Intercompartmental Defects with Magnetic Resonance Imaging (MRI)
US10857173B2 (en) 2017-07-25 2020-12-08 Taris Biomedical Llc Methods of treating tumor metastasis
EP3675900A4 (en) 2017-08-28 2021-05-05 Revance Therapeutics, Inc. Transmucosal botulinum toxin compositions, kits, and methods for treating bladder disorders
JOP20200124A1 (ar) 2017-11-08 2020-05-20 Taris Biomedical Llc طُرق لعلاج سرطان المثانة باستخدام جيمسيتابين وعلاج مدوامة لذلك
KR102398743B1 (ko) * 2020-09-03 2022-05-16 충남대학교병원 초음파유도 마이크로버블을 포함하는 배뇨장애 치료제 조성물
TWI760996B (zh) * 2020-12-25 2022-04-11 姜秉均 含有疏水性物質的奈米組成物及其製備方法與用途
CN117598911A (zh) * 2022-12-09 2024-02-27 崔蕾 一种肉毒素脂质体透明质酸凝胶的制备方法
CN117883383A (zh) * 2023-12-26 2024-04-16 中国康复研究中心 一种作为A型肉毒素载体的TiO2纳米粒子及制备方法
US12272439B1 (en) 2024-05-06 2025-04-08 Immunitybio, Inc. Distributed ledger for medicament administration tracking

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3693209B2 (ja) * 1996-04-11 2005-09-07 三菱化学株式会社 閉鎖小胞の製造方法
WO2003015698A2 (en) * 2001-08-13 2003-02-27 University Of Pittsburgh Application of lipid vehicles and use for drug delivery
US20030224020A1 (en) * 2002-05-31 2003-12-04 Zabudkin Alexander F. Pharmaceutical preparation of botulinum neurotoxin, methods of synthesis and methods of clinical use
US20040067235A1 (en) 2002-07-29 2004-04-08 Rajiv Doshi Methods for the use of neurotoxin in the treatment of urologic disorders
JP2006508126A (ja) * 2002-11-06 2006-03-09 アザヤ セラピューティクス インコーポレイティッド 薬学的製剤のタンパク質安定化されたリポソーム製剤
WO2007044748A2 (en) 2005-10-11 2007-04-19 University Of Pittsburgh Sphingomyelin liposomes for the treatment of hyperactive bladder disorders

Also Published As

Publication number Publication date
US20120093920A1 (en) 2012-04-19
WO2009139984A2 (en) 2009-11-19
EP2273976A2 (en) 2011-01-19
JP2011516497A (ja) 2011-05-26
EP2599476A1 (en) 2013-06-05
KR20100131471A (ko) 2010-12-15
JP2014062125A (ja) 2014-04-10
MX2010010635A (es) 2010-12-17
AU2009246834B2 (en) 2012-12-06
CN102065841A (zh) 2011-05-18
WO2009139984A3 (en) 2010-03-04
CA2720523A1 (en) 2009-11-19
BRPI0911098A2 (pt) 2015-10-06
CA2720523C (en) 2013-12-17
AU2009246834A1 (en) 2009-11-19

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