JP5512975B2 - タンパク質キナーゼ阻害薬 - Google Patents

タンパク質キナーゼ阻害薬 Download PDF

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Publication number
JP5512975B2
JP5512975B2 JP2008548736A JP2008548736A JP5512975B2 JP 5512975 B2 JP5512975 B2 JP 5512975B2 JP 2008548736 A JP2008548736 A JP 2008548736A JP 2008548736 A JP2008548736 A JP 2008548736A JP 5512975 B2 JP5512975 B2 JP 5512975B2
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JP
Japan
Prior art keywords
pyrazolo
benzimidazol
amine
trans
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2008548736A
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English (en)
Japanese (ja)
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JP2009522284A (ja
JP2009522284A5 (https=
Inventor
シエパード，ジヨージ
ワン，ギヤリー
パラツツオ，フアビオ
ベル，ランデイ
マンテイ，ロバート
ワン，ジエイ
ハバード，ロバート
カワイ，メグミ
エリクソン，スコツト
バマウン，ヌエ
フイダンツエ，ステイーブ
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AbbVie Inc
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AbbVie Inc
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Publication of JP2009522284A publication Critical patent/JP2009522284A/ja
Publication of JP2009522284A5 publication Critical patent/JP2009522284A5/ja
Application granted granted Critical
Publication of JP5512975B2 publication Critical patent/JP5512975B2/ja
Expired - Fee Related legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2008548736A 2005-12-29 2006-12-28 タンパク質キナーゼ阻害薬 Expired - Fee Related JP5512975B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75468505P 2005-12-29 2005-12-29
US60/754,685 2005-12-29
PCT/US2006/049461 WO2007079164A2 (en) 2005-12-29 2006-12-28 Protein kinase inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013254737A Division JP2014088397A (ja) 2005-12-29 2013-12-10 タンパク質キナーゼ阻害薬

Publications (3)

Publication Number Publication Date
JP2009522284A JP2009522284A (ja) 2009-06-11
JP2009522284A5 JP2009522284A5 (https=) 2013-03-28
JP5512975B2 true JP5512975B2 (ja) 2014-06-04

Family

ID=38137349

Family Applications (2)

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JP2008548736A Expired - Fee Related JP5512975B2 (ja) 2005-12-29 2006-12-28 タンパク質キナーゼ阻害薬
JP2013254737A Pending JP2014088397A (ja) 2005-12-29 2013-12-10 タンパク質キナーゼ阻害薬

Family Applications After (1)

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JP2013254737A Pending JP2014088397A (ja) 2005-12-29 2013-12-10 タンパク質キナーゼ阻害薬

Country Status (8)

Country Link
US (1) US7772231B2 (https=)
EP (1) EP1973917B1 (https=)
JP (2) JP5512975B2 (https=)
CN (1) CN101389630A (https=)
CA (1) CA2635231C (https=)
ES (1) ES2545907T3 (https=)
TW (2) TW200801008A (https=)
WO (1) WO2007079164A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014088397A (ja) * 2005-12-29 2014-05-15 Abbvie Inc タンパク質キナーゼ阻害薬

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Also Published As

Publication number Publication date
ES2545907T3 (es) 2015-09-16
CN101389630A (zh) 2009-03-18
WO2007079164A2 (en) 2007-07-12
EP1973917B1 (en) 2015-06-10
JP2009522284A (ja) 2009-06-11
CA2635231A1 (en) 2007-07-12
EP1973917A2 (en) 2008-10-01
US7772231B2 (en) 2010-08-10
WO2007079164A3 (en) 2007-09-27
JP2014088397A (ja) 2014-05-15
TW201307354A (zh) 2013-02-16
US20070203143A1 (en) 2007-08-30
TW200801008A (en) 2008-01-01
CA2635231C (en) 2014-07-15

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