JP5467243B2 - 可溶性羽毛ケラチン蛋白質の製造方法 - Google Patents
可溶性羽毛ケラチン蛋白質の製造方法 Download PDFInfo
- Publication number
- JP5467243B2 JP5467243B2 JP2008156122A JP2008156122A JP5467243B2 JP 5467243 B2 JP5467243 B2 JP 5467243B2 JP 2008156122 A JP2008156122 A JP 2008156122A JP 2008156122 A JP2008156122 A JP 2008156122A JP 5467243 B2 JP5467243 B2 JP 5467243B2
- Authority
- JP
- Japan
- Prior art keywords
- keratin protein
- solution
- feather keratin
- soluble
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 101710200191 Feather keratin Proteins 0.000 title claims description 52
- 238000004519 manufacturing process Methods 0.000 title claims description 22
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 claims description 66
- 210000003746 feather Anatomy 0.000 claims description 39
- 239000007800 oxidant agent Substances 0.000 claims description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 18
- XUXNAKZDHHEHPC-UHFFFAOYSA-M sodium bromate Chemical compound [Na+].[O-]Br(=O)=O XUXNAKZDHHEHPC-UHFFFAOYSA-M 0.000 claims description 18
- 102000004169 proteins and genes Human genes 0.000 claims description 9
- 108090000623 proteins and genes Proteins 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 55
- 239000000126 substance Substances 0.000 description 30
- 238000006243 chemical reaction Methods 0.000 description 28
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 24
- 108010076876 Keratins Proteins 0.000 description 16
- 102000011782 Keratins Human genes 0.000 description 16
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 15
- 241000287828 Gallus gallus Species 0.000 description 12
- 125000003396 thiol group Chemical group [H]S* 0.000 description 12
- 238000011282 treatment Methods 0.000 description 12
- DLLMHEDYJQACRM-UHFFFAOYSA-N 2-(carboxymethyldisulfanyl)acetic acid Chemical compound OC(=O)CSSCC(O)=O DLLMHEDYJQACRM-UHFFFAOYSA-N 0.000 description 9
- 125000002228 disulfide group Chemical group 0.000 description 8
- 235000018102 proteins Nutrition 0.000 description 8
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 230000007935 neutral effect Effects 0.000 description 7
- 238000007254 oxidation reaction Methods 0.000 description 7
- 238000006722 reduction reaction Methods 0.000 description 7
- 239000007864 aqueous solution Substances 0.000 description 6
- 235000013330 chicken meat Nutrition 0.000 description 6
- 239000003599 detergent Substances 0.000 description 6
- 239000002699 waste material Substances 0.000 description 6
- 238000004090 dissolution Methods 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- 241000272814 Anser sp. Species 0.000 description 4
- LEVWYRKDKASIDU-IMJSIDKUSA-N cystine group Chemical group C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 108090000765 processed proteins & peptides Proteins 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000003638 chemical reducing agent Substances 0.000 description 3
- 238000011033 desalting Methods 0.000 description 3
- 238000001962 electrophoresis Methods 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 230000003647 oxidation Effects 0.000 description 3
- 230000001590 oxidative effect Effects 0.000 description 3
- 238000001556 precipitation Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000001632 sodium acetate Substances 0.000 description 3
- 235000017281 sodium acetate Nutrition 0.000 description 3
- WCRCOODEFQFSPO-VKHMYHEASA-N 2-[[(2S)-2-aminopropanoyl]disulfanyl]acetic acid Chemical group C[C@H](N)C(=O)SSCC(O)=O WCRCOODEFQFSPO-VKHMYHEASA-N 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 108010049062 beta-Keratins Proteins 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 235000019441 ethanol Nutrition 0.000 description 2
- 238000005194 fractionation Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- CRWJEUDFKNYSBX-UHFFFAOYSA-N sodium;hypobromite Chemical compound [Na+].Br[O-] CRWJEUDFKNYSBX-UHFFFAOYSA-N 0.000 description 2
- 230000007928 solubilization Effects 0.000 description 2
- 238000005063 solubilization Methods 0.000 description 2
- 230000003381 solubilizing effect Effects 0.000 description 2
- 238000006276 transfer reaction Methods 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 238000001291 vacuum drying Methods 0.000 description 2
- 241000271566 Aves Species 0.000 description 1
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000006664 bond formation reaction Methods 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 150000001793 charged compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 238000002523 gelfiltration Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000000269 nucleophilic effect Effects 0.000 description 1
- 239000012460 protein solution Substances 0.000 description 1
- 238000007348 radical reaction Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- GNBVPFITFYNRCN-UHFFFAOYSA-M sodium thioglycolate Chemical compound [Na+].[O-]C(=O)CS GNBVPFITFYNRCN-UHFFFAOYSA-M 0.000 description 1
- 229940046307 sodium thioglycolate Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
- C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Gastroenterology & Hepatology (AREA)
- Materials Engineering (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008156122A JP5467243B2 (ja) | 2008-06-16 | 2008-06-16 | 可溶性羽毛ケラチン蛋白質の製造方法 |
| PCT/JP2009/002451 WO2009153923A1 (ja) | 2008-06-16 | 2009-06-02 | 可溶性羽毛ケラチン蛋白質の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008156122A JP5467243B2 (ja) | 2008-06-16 | 2008-06-16 | 可溶性羽毛ケラチン蛋白質の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009298737A JP2009298737A (ja) | 2009-12-24 |
| JP2009298737A5 JP2009298737A5 (enExample) | 2010-04-15 |
| JP5467243B2 true JP5467243B2 (ja) | 2014-04-09 |
Family
ID=41433849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008156122A Active JP5467243B2 (ja) | 2008-06-16 | 2008-06-16 | 可溶性羽毛ケラチン蛋白質の製造方法 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP5467243B2 (enExample) |
| WO (1) | WO2009153923A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5411655B2 (ja) * | 2008-12-03 | 2014-02-12 | 株式会社ミルボン | 毛髪処理方法及び毛髪処理剤 |
| JP2011144127A (ja) * | 2010-01-13 | 2011-07-28 | Milbon Co Ltd | 毛髪処理剤及び毛髪処理剤用原料 |
| KR101951923B1 (ko) * | 2009-06-12 | 2019-02-25 | 가부시키가이샤 미르본 | 모발처리제 및 모발처리제용 원료 |
| US8575313B2 (en) | 2010-11-19 | 2013-11-05 | Universiti Malaysia Pahang | Process for extracting keratin |
| CN119662303B (zh) * | 2025-02-17 | 2025-06-17 | 淄博凯美可工贸有限公司 | 一种原油预处理破乳剂的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07126296A (ja) * | 1993-05-24 | 1995-05-16 | Kao Corp | 可溶化蛋白質 |
| JPH092919A (ja) * | 1995-06-19 | 1997-01-07 | Kao Corp | 新規ゲル化剤及びゲル組成物 |
| JP2007176863A (ja) * | 2005-12-28 | 2007-07-12 | Gunei Shoji Kk | 可溶化蛋白質の製造方法 |
-
2008
- 2008-06-16 JP JP2008156122A patent/JP5467243B2/ja active Active
-
2009
- 2009-06-02 WO PCT/JP2009/002451 patent/WO2009153923A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009153923A1 (ja) | 2009-12-23 |
| JP2009298737A (ja) | 2009-12-24 |
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