JP5426181B2 - 検体処理システム、細胞画像分類装置、及び検体処理方法 - Google Patents
検体処理システム、細胞画像分類装置、及び検体処理方法 Download PDFInfo
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- JP5426181B2 JP5426181B2 JP2009011303A JP2009011303A JP5426181B2 JP 5426181 B2 JP5426181 B2 JP 5426181B2 JP 2009011303 A JP2009011303 A JP 2009011303A JP 2009011303 A JP2009011303 A JP 2009011303A JP 5426181 B2 JP5426181 B2 JP 5426181B2
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/98—Detection or correction of errors, e.g. by rescanning the pattern or by human intervention; Evaluation of the quality of the acquired patterns
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/98—Detection or correction of errors, e.g. by rescanning the pattern or by human intervention; Evaluation of the quality of the acquired patterns
- G06V10/987—Detection or correction of errors, e.g. by rescanning the pattern or by human intervention; Evaluation of the quality of the acquired patterns with the intervention of an operator
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
- G06V20/693—Acquisition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N1/312—Apparatus therefor for samples mounted on planar substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N2015/1472—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle with colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N2035/00891—Displaying information to the operator
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N2035/0097—Control arrangements for automatic analysers monitoring reactions as a function of time
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00613—Quality control
- G01N35/00623—Quality control of instruments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00693—Calibration
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Multimedia (AREA)
- Theoretical Computer Science (AREA)
- Quality & Reliability (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Signal Processing (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009011303A JP5426181B2 (ja) | 2009-01-21 | 2009-01-21 | 検体処理システム、細胞画像分類装置、及び検体処理方法 |
| CN2009102637051A CN101782524B (zh) | 2009-01-21 | 2009-12-30 | 细胞图像处理装置、细胞图像处理方法以及计算机系统 |
| US12/690,591 US20100183216A1 (en) | 2009-01-21 | 2010-01-20 | Cell image processing apparatus, cell image processing method and computer program product |
| EP10000521.4A EP2211165B1 (en) | 2009-01-21 | 2010-01-20 | Cell image processing apparatus, cell image processing method and computer program product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009011303A JP5426181B2 (ja) | 2009-01-21 | 2009-01-21 | 検体処理システム、細胞画像分類装置、及び検体処理方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010169484A JP2010169484A (ja) | 2010-08-05 |
| JP2010169484A5 JP2010169484A5 (enExample) | 2012-02-23 |
| JP5426181B2 true JP5426181B2 (ja) | 2014-02-26 |
Family
ID=42109966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009011303A Expired - Fee Related JP5426181B2 (ja) | 2009-01-21 | 2009-01-21 | 検体処理システム、細胞画像分類装置、及び検体処理方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100183216A1 (enExample) |
| EP (1) | EP2211165B1 (enExample) |
| JP (1) | JP5426181B2 (enExample) |
| CN (1) | CN101782524B (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8781201B2 (en) * | 2009-03-04 | 2014-07-15 | Robert E. Sandstrom | Method of operating a pathology laboratory |
| US9522396B2 (en) | 2010-12-29 | 2016-12-20 | S.D. Sight Diagnostics Ltd. | Apparatus and method for automatic detection of pathogens |
| CN102735609A (zh) * | 2011-03-31 | 2012-10-17 | 西门子公司 | 一种体液成像系统、方法及景深扩展成像装置 |
| CN108318409A (zh) | 2011-06-17 | 2018-07-24 | 罗氏血液诊断股份有限公司 | 用于样本显示与查看的系统和方法 |
| JP5869239B2 (ja) | 2011-06-21 | 2016-02-24 | 浜松ホトニクス株式会社 | 光測定装置、光測定方法、及び光測定プログラム |
| WO2012176783A1 (ja) * | 2011-06-21 | 2012-12-27 | 浜松ホトニクス株式会社 | 光測定装置、光測定方法、及び光測定プログラム |
| US9459196B2 (en) | 2011-07-22 | 2016-10-04 | Roche Diagnostics Hematology, Inc. | Blood analyzer calibration and assessment |
| WO2013098821A1 (en) | 2011-12-29 | 2013-07-04 | Parasight Ltd. | Methods and systems for detecting a pathogen in a biological sample |
| US9164015B2 (en) * | 2012-06-29 | 2015-10-20 | General Electric Company | Systems and methods for processing and imaging of biological samples |
| US9817221B2 (en) | 2012-06-29 | 2017-11-14 | General Electric Company | Systems and methods for processing and imaging of biological samples |
| US9389229B2 (en) | 2012-07-18 | 2016-07-12 | Theranos, Inc. | Methods for detecting and measuring aggregation |
| JP5376024B1 (ja) * | 2012-08-23 | 2013-12-25 | 富士ゼロックス株式会社 | 画像処理装置、プログラム及び画像処理システム |
| JP5333635B1 (ja) * | 2012-08-23 | 2013-11-06 | 富士ゼロックス株式会社 | 画像処理装置、プログラム及び画像処理システム |
| EP3869257B1 (en) | 2013-05-23 | 2024-05-08 | S.D. Sight Diagnostics Ltd. | Method and system for imaging a cell sample |
| IL227276A0 (en) | 2013-07-01 | 2014-03-06 | Parasight Ltd | A method and system for preparing a monolayer of cells, particularly suitable for diagnosis |
| CN103364242B (zh) * | 2013-07-11 | 2015-05-13 | 四川美生科技有限公司 | 全自动医学检验血液推片染色机 |
| WO2015013605A1 (en) * | 2013-07-26 | 2015-01-29 | Abbott Point Of Care, Inc. | Method and apparatus for producing an image of undiluted whole blood sample having wright stain coloration |
| EP3955042B1 (en) | 2013-08-26 | 2024-08-21 | S.D. Sight Diagnostics Ltd. | Digital microscopy systems, methods and computer program products |
| WO2015182256A1 (ja) * | 2014-05-30 | 2015-12-03 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| US10482595B2 (en) | 2014-08-27 | 2019-11-19 | S.D. Sight Diagnostics Ltd. | System and method for calculating focus variation for a digital microscope |
| US9298968B1 (en) * | 2014-09-12 | 2016-03-29 | Flagship Biosciences, Inc. | Digital image analysis of inflammatory cells and mediators of inflammation |
| JP6342285B2 (ja) | 2014-09-30 | 2018-06-13 | シスメックス株式会社 | 粒子分析装置における異常判定方法、分析装置における精度管理方法、および粒子分析装置 |
| CN104459172B (zh) * | 2014-11-28 | 2016-08-17 | 武汉兰丁医学高科技有限公司 | 一种自动化骨髓样本处理装置及其自动化分析、阅片方法 |
| JP6134348B2 (ja) | 2015-03-31 | 2017-05-24 | シスメックス株式会社 | 細胞撮像装置及び細胞撮像方法 |
| JP2017009314A (ja) * | 2015-06-17 | 2017-01-12 | 株式会社Screenホールディングス | 教示データの作成支援方法、作成支援装置、プログラムおよびプログラム記録媒体 |
| CN107924462A (zh) * | 2015-08-24 | 2018-04-17 | 皇家飞利浦有限公司 | 数字病理学中的服务器‑客户机架构 |
| US11085940B2 (en) * | 2015-08-26 | 2021-08-10 | Hitachi High-Tech Corporation | Automatic analyzer |
| AU2016322966B2 (en) | 2015-09-17 | 2021-10-14 | S.D. Sight Diagnostics Ltd | Methods and apparatus for detecting an entity in a bodily sample |
| WO2017168411A1 (en) | 2016-03-30 | 2017-10-05 | S.D. Sight Diagnostics Ltd | Image processing device for identifying blood parasites |
| CN109564209B (zh) | 2016-05-11 | 2022-05-31 | 思迪赛特诊断有限公司 | 对样品实施的光学测量 |
| US11307196B2 (en) | 2016-05-11 | 2022-04-19 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| EP3321851A3 (en) * | 2016-11-09 | 2018-08-01 | AmCad BioMed Corporation | Cytological image processing device, and method for quantifying characteristics of cytological image |
| CN108537092B (zh) * | 2017-03-02 | 2020-11-10 | 爱威科技股份有限公司 | 变异红细胞识别方法及装置 |
| EP3710810B1 (en) | 2017-11-14 | 2023-09-06 | S.D. Sight Diagnostics Ltd. | Sample carrier for optical measurements |
| CA3082718A1 (en) * | 2017-11-22 | 2019-05-31 | Grifols Diagnostic Solutions Inc. | Systems and methods for biological sample laboratory screening |
| KR102122068B1 (ko) * | 2018-11-19 | 2020-06-12 | 노을 주식회사 | 이미지 분석 시스템 및 분석 방법 |
| JP7376245B2 (ja) * | 2019-03-29 | 2023-11-08 | シスメックス株式会社 | 蛍光画像分析装置及び蛍光画像分析方法 |
| JP7403965B2 (ja) * | 2019-03-29 | 2023-12-25 | シスメックス株式会社 | 蛍光画像分析装置及び蛍光画像分析方法 |
| JP2021040590A (ja) | 2019-09-13 | 2021-03-18 | シスメックス株式会社 | 細胞画像解析方法、細胞画像解析装置、プログラム、及び細胞画像解析システム |
| JP7677972B2 (ja) | 2019-12-12 | 2025-05-15 | エス.ディー.サイト ダイアグノスティックス リミテッド | カラー血液スミア画像の人工的な生成 |
| AU2020400401A1 (en) | 2019-12-12 | 2022-06-02 | S.D. Sight Diagnostics Ltd | Analyzing an analyte disposed within a medium |
| CN112213503B (zh) * | 2020-09-03 | 2025-10-17 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析系统、图像分析系统及其处理样本图像的方法 |
| CN114544989A (zh) * | 2020-11-25 | 2022-05-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种样本分析装置和方法 |
| CN112881737A (zh) * | 2021-01-27 | 2021-06-01 | 湖南索莱智能科技有限公司 | 一种全自动生物样品分析一体化设备及控制方法 |
| CN113515077A (zh) * | 2021-04-23 | 2021-10-19 | 重庆德方信息技术有限公司 | 人体细胞染色过程监控系统及方法 |
| US20230289962A1 (en) * | 2022-03-09 | 2023-09-14 | Sysmex Corporation | Method of generating quality control information, apparatus for generating quality control information, and program |
| CN116481981A (zh) * | 2023-04-28 | 2023-07-25 | 苏州睿仟科技有限公司 | 一种细胞玻片成像系统、方法及计算机设备 |
| CN118465292B (zh) * | 2024-07-15 | 2024-09-10 | 深圳市贝安特医疗技术有限公司 | 设备染色稳定性周期自查方法及系统 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4097845A (en) * | 1976-11-01 | 1978-06-27 | Rush-Presbyterian-St. Luke's Medical Center | Method of and an apparatus for automatic classification of red blood cells |
| JPS5379599A (en) * | 1976-12-23 | 1978-07-14 | Toa Medical Electronics | Automatic blood analyzer |
| JPS60162955A (ja) * | 1984-02-03 | 1985-08-24 | Hitachi Ltd | 血球自動分析装置 |
| JPH0652263B2 (ja) * | 1985-12-10 | 1994-07-06 | 株式会社日立製作所 | 細胞分析装置 |
| ATE67044T1 (de) * | 1987-02-05 | 1991-09-15 | Contraves Ag | Verfahren und vorrichtung zum bestimmen von schwellenwerten bei der teilchenanalyse einer fluessigkeit. |
| JP3169598B2 (ja) * | 1990-07-06 | 2001-05-28 | 株式会社日立製作所 | 自動分析方法および自動分析装置 |
| JPH055733A (ja) * | 1991-06-28 | 1993-01-14 | Sanyo Electric Co Ltd | 血液像検査装置 |
| US5768412A (en) * | 1994-09-19 | 1998-06-16 | Hitachi, Ltd. | Region segmentation method for particle images and apparatus thereof |
| JP3189608B2 (ja) * | 1995-02-01 | 2001-07-16 | 株式会社日立製作所 | フロー式粒子画像解析方法 |
| JPH09257689A (ja) * | 1996-03-27 | 1997-10-03 | Hitachi Ltd | 粒子解析装置 |
| JPH10275150A (ja) * | 1997-03-28 | 1998-10-13 | Toa Medical Electronics Co Ltd | 画像ファイリングシステム |
| JP2002140692A (ja) * | 2000-10-30 | 2002-05-17 | Sysmex Corp | 画像解析装置 |
| CN1166951C (zh) * | 2002-08-28 | 2004-09-15 | 彭黎明 | 无创性血细胞参数定量测定方法 |
| US20050051723A1 (en) * | 2003-07-23 | 2005-03-10 | Neagle Bradley D. | Examination systems for biological samples |
| JP4649828B2 (ja) * | 2003-10-17 | 2011-03-16 | Jfeスチール株式会社 | 画像処理装置の異常の判定方法 |
| JP4528529B2 (ja) * | 2004-01-20 | 2010-08-18 | 株式会社東芝 | 超音波診断装置及び超音波画像データ処理方法 |
| JP4542386B2 (ja) * | 2004-07-30 | 2010-09-15 | シスメックス株式会社 | 画像表示システム、画像提供装置、画像表示装置、およびコンピュータプログラム |
| JP4964446B2 (ja) * | 2005-09-14 | 2012-06-27 | シスメックス株式会社 | 分析装置及び検体情報処理プログラム |
| JP4229154B2 (ja) * | 2006-08-31 | 2009-02-25 | ソニー株式会社 | 画像処理方法 |
| JP5063999B2 (ja) * | 2006-11-30 | 2012-10-31 | シスメックス株式会社 | 血液像分析装置 |
| JP2008212017A (ja) * | 2007-03-01 | 2008-09-18 | Nikon Corp | 細胞状態判定装置、および細胞状態判定方法 |
| WO2009009779A2 (en) * | 2007-07-11 | 2009-01-15 | Cualing Hernani D | Automated bone marrow cellularity determination |
-
2009
- 2009-01-21 JP JP2009011303A patent/JP5426181B2/ja not_active Expired - Fee Related
- 2009-12-30 CN CN2009102637051A patent/CN101782524B/zh active Active
-
2010
- 2010-01-20 EP EP10000521.4A patent/EP2211165B1/en not_active Not-in-force
- 2010-01-20 US US12/690,591 patent/US20100183216A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010169484A (ja) | 2010-08-05 |
| EP2211165B1 (en) | 2017-07-26 |
| EP2211165A3 (en) | 2015-07-08 |
| CN101782524B (zh) | 2013-09-18 |
| CN101782524A (zh) | 2010-07-21 |
| EP2211165A2 (en) | 2010-07-28 |
| US20100183216A1 (en) | 2010-07-22 |
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