JP5406529B2 - カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム - Google Patents

カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム Download PDF

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JP5406529B2
JP5406529B2 JP2008537930A JP2008537930A JP5406529B2 JP 5406529 B2 JP5406529 B2 JP 5406529B2 JP 2008537930 A JP2008537930 A JP 2008537930A JP 2008537930 A JP2008537930 A JP 2008537930A JP 5406529 B2 JP5406529 B2 JP 5406529B2
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matrix
agent
lipophilic
hydrogel
rate regulating
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JP2009513657A (ja
JP2009513657A5 (enExample
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カルナカル スクル，
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バナー ファーマキャプス， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008537930A 2005-10-26 2006-10-26 カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム Expired - Fee Related JP5406529B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73051405P 2005-10-26 2005-10-26
US60/730,514 2005-10-26
PCT/US2006/041722 WO2007050724A2 (en) 2005-10-26 2006-10-26 Lipophilic vehicle-based dual controlled release matrix system as capsule fill

Related Child Applications (1)

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JP2013133882A Division JP2013216681A (ja) 2005-10-26 2013-06-26 カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム

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JP2009513657A JP2009513657A (ja) 2009-04-02
JP2009513657A5 JP2009513657A5 (enExample) 2009-12-17
JP5406529B2 true JP5406529B2 (ja) 2014-02-05

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JP2008537930A Expired - Fee Related JP5406529B2 (ja) 2005-10-26 2006-10-26 カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム
JP2013133882A Pending JP2013216681A (ja) 2005-10-26 2013-06-26 カプセル充墳物としての親油性ベヒクルに基づく二重制御された放出マトリクスシステム

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Country Status (6)

Country Link
US (1) US8293270B2 (enExample)
EP (1) EP1951208A2 (enExample)
JP (2) JP5406529B2 (enExample)
CN (1) CN101351196B (enExample)
CA (1) CA2627351C (enExample)
WO (1) WO2007050724A2 (enExample)

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FI3225243T3 (fi) 2007-04-25 2025-10-13 Opko Renal Llc Menetelmä sekundaarisen hyperparatyreoosin turvalliseen ja tehokkaaseen hoitoon ja ehkäisyyn kroonisen munuaistaudin yhteydessä
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US8962239B2 (en) 2008-04-02 2015-02-24 Opko Renal, Llc Methods useful for vitamin D deficiency and related disorders
JP5613396B2 (ja) * 2008-10-22 2014-10-22 参天製薬株式会社 腸管吸収性を改善する医薬組成物
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EP3765002B1 (en) * 2018-03-15 2025-03-05 Cerecin Inc. Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto
CN113301884A (zh) * 2018-09-13 2021-08-24 夫特弗制药私人有限公司 非水性化疗口服悬浮液
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Also Published As

Publication number Publication date
US8293270B2 (en) 2012-10-23
JP2013216681A (ja) 2013-10-24
EP1951208A2 (en) 2008-08-06
JP2009513657A (ja) 2009-04-02
WO2007050724A2 (en) 2007-05-03
CA2627351C (en) 2012-05-01
US20070092560A1 (en) 2007-04-26
CA2627351A1 (en) 2007-05-03
WO2007050724A3 (en) 2007-09-20
CN101351196A (zh) 2009-01-21
CN101351196B (zh) 2013-07-03

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