JP5368317B2 - 新規なインドール誘導体それらの製造方法および特に抗菌剤としてのそれらの使用 - Google Patents

新規なインドール誘導体それらの製造方法および特に抗菌剤としてのそれらの使用 Download PDF

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Publication number
JP5368317B2
JP5368317B2 JP2009547728A JP2009547728A JP5368317B2 JP 5368317 B2 JP5368317 B2 JP 5368317B2 JP 2009547728 A JP2009547728 A JP 2009547728A JP 2009547728 A JP2009547728 A JP 2009547728A JP 5368317 B2 JP5368317 B2 JP 5368317B2
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Japan
Prior art keywords
group
compound
hydrogen atom
formula
defined above
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JP2009547728A
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English (en)
Japanese (ja)
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JP2010517983A5 (cg-RX-API-DMAC10.html
JP2010517983A (ja
Inventor
デニス，ジャン−ノエル，マリー，レオン
ギンシャール，グザビエ，ジャン，ジョルジュ，マリー
ニー ラフォン，ニコル，ジャンヌ モロー
ノイヴィル，リュック
ヴァレ，ヤニック
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Joseph Fourier University
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Joseph Fourier University
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP2009547728A 2007-02-01 2008-01-31 新規なインドール誘導体それらの製造方法および特に抗菌剤としてのそれらの使用 Expired - Fee Related JP5368317B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0700717A FR2912133B1 (fr) 2007-02-01 2007-02-01 Nouveaux derives indoliques,leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens
FR0700717 2007-02-01
PCT/FR2008/000118 WO2008110690A2 (fr) 2007-02-01 2008-01-31 Nouveaux derives indoliques, leurs procedes de preparation et leurs utilisations notamment en tant qu'antibacteriens

Publications (3)

Publication Number Publication Date
JP2010517983A JP2010517983A (ja) 2010-05-27
JP2010517983A5 JP2010517983A5 (cg-RX-API-DMAC10.html) 2010-12-02
JP5368317B2 true JP5368317B2 (ja) 2013-12-18

Family

ID=38476052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009547728A Expired - Fee Related JP5368317B2 (ja) 2007-02-01 2008-01-31 新規なインドール誘導体それらの製造方法および特に抗菌剤としてのそれらの使用

Country Status (9)

Country Link
US (1) US8343964B2 (cg-RX-API-DMAC10.html)
EP (1) EP2121601B8 (cg-RX-API-DMAC10.html)
JP (1) JP5368317B2 (cg-RX-API-DMAC10.html)
CN (1) CN101652346B (cg-RX-API-DMAC10.html)
AU (1) AU2008224776B2 (cg-RX-API-DMAC10.html)
CA (1) CA2677146C (cg-RX-API-DMAC10.html)
FR (1) FR2912133B1 (cg-RX-API-DMAC10.html)
RU (1) RU2464261C2 (cg-RX-API-DMAC10.html)
WO (1) WO2008110690A2 (cg-RX-API-DMAC10.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011060976A1 (en) 2009-11-20 2011-05-26 Universite De Liege Tryptamine-derived compounds as antibacterial agents
FR2969150B1 (fr) * 2010-12-20 2013-07-26 Centre Nat Rech Scient Nouvelles molecules indoliques demontrant des activites antibacteriennes dans une variete de bacteries a gram-negatif et positif dont des bacteries multidrogues-resistantes
ES2464598T3 (es) 2011-07-22 2014-06-03 Université Joseph Fourier Nuevos derivados bis-indólicos, procedimiento para su preparación, y sus utilizaciones como fármaco
EP2548865B1 (en) 2011-07-22 2014-03-05 Université Joseph Fourier Novel bis-indolic derivatives, their uses in particular as antibacterials
EP2639220A1 (en) * 2012-03-15 2013-09-18 Omnia Molecular, S. L. Indole derivatives and their use as antibiotics
CN103664733B (zh) * 2013-12-10 2016-04-20 邯郸惠达化工有限公司 一种吲哚啉的制备方法
CN105669519B (zh) * 2016-01-04 2018-01-05 北方民族大学 吲哚类化合物、制备方法及其作为抗耐药菌药物的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492694A (en) * 1983-04-12 1985-01-08 Eli Lilly And Company Indolylglycyl cephalosporin derivatives
US5328902A (en) * 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
JP4387804B2 (ja) * 2001-04-06 2009-12-24 アフィニアム・ファーマシューティカルズ・インコーポレイテッド ＦａｂＩ阻害剤
EP1608377B1 (en) 2003-03-17 2008-10-01 Affinium Pharmaceuticals, Inc. Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
DE10320453A1 (de) * 2003-05-08 2004-11-25 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Bioisostere von Actinonin

Also Published As

Publication number Publication date
US20100144726A1 (en) 2010-06-10
FR2912133B1 (fr) 2009-04-24
CA2677146A1 (fr) 2008-09-18
WO2008110690A3 (fr) 2009-03-19
RU2464261C2 (ru) 2012-10-20
CA2677146C (fr) 2016-11-15
CN101652346A (zh) 2010-02-17
EP2121601B1 (fr) 2016-06-15
FR2912133A1 (fr) 2008-08-08
RU2009132657A (ru) 2011-03-10
WO2008110690A2 (fr) 2008-09-18
CN101652346B (zh) 2013-10-30
JP2010517983A (ja) 2010-05-27
EP2121601B8 (fr) 2016-12-07
AU2008224776A1 (en) 2008-09-18
AU2008224776B2 (en) 2012-09-06
US8343964B2 (en) 2013-01-01
EP2121601A2 (fr) 2009-11-25

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