JP5341526B2 - 免疫調節化合物、及び炎症性サイトカインの過剰産生に関連する疾患の治療 - Google Patents

免疫調節化合物、及び炎症性サイトカインの過剰産生に関連する疾患の治療 Download PDF

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JP5341526B2
JP5341526B2 JP2008557846A JP2008557846A JP5341526B2 JP 5341526 B2 JP5341526 B2 JP 5341526B2 JP 2008557846 A JP2008557846 A JP 2008557846A JP 2008557846 A JP2008557846 A JP 2008557846A JP 5341526 B2 JP5341526 B2 JP 5341526B2
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configuration
mice
cooh
oxo
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JP2009529523A (ja
JP2009529523A5 (enExample
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バウアー，ジャック
シャバロリ，カルロ
ムテル，ステファン
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OM Pharma SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
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    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2008557846A 2006-03-09 2007-03-09 免疫調節化合物、及び炎症性サイトカインの過剰産生に関連する疾患の治療 Expired - Fee Related JP5341526B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IBPCT/IB2006/050748 2006-03-09
IBPCT/IB2006/050748 2006-03-09
PCT/IB2007/000567 WO2007102081A2 (en) 2006-03-09 2007-03-09 Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines

Publications (3)

Publication Number Publication Date
JP2009529523A JP2009529523A (ja) 2009-08-20
JP2009529523A5 JP2009529523A5 (enExample) 2010-02-18
JP5341526B2 true JP5341526B2 (ja) 2013-11-13

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JP2008557846A Expired - Fee Related JP5341526B2 (ja) 2006-03-09 2007-03-09 免疫調節化合物、及び炎症性サイトカインの過剰産生に関連する疾患の治療

Country Status (14)

Country Link
US (3) US7915240B2 (enExample)
EP (1) EP2051728A4 (enExample)
JP (1) JP5341526B2 (enExample)
KR (1) KR20080105048A (enExample)
CN (1) CN101511379A (enExample)
AU (1) AU2007222135B2 (enExample)
BR (1) BRPI0708363A2 (enExample)
CA (1) CA2645053A1 (enExample)
IL (1) IL192837A (enExample)
MX (1) MX2008011360A (enExample)
NO (1) NO20084195L (enExample)
RU (1) RU2498813C2 (enExample)
WO (1) WO2007102081A2 (enExample)
ZA (1) ZA200806266B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2645053A1 (en) * 2006-03-09 2007-09-13 Om Pharma Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines
KR101108161B1 (ko) 2009-12-24 2012-01-31 삼성모바일디스플레이주식회사 유기 발광 표시 장치 및 그 제조방법
US10065978B2 (en) 2015-11-24 2018-09-04 University Of South Carolina Cysteine-modifying substrate analogue inhibitors of ribose 5-phosphate isomerase for parasitic diseases, along with methods of their formation and use
US10682359B2 (en) 2017-03-31 2020-06-16 University Of South Carolina Inhibitors of glucose kinases, along with methods of their formation and use
US11059842B2 (en) 2019-04-29 2021-07-13 University Of South Carolina Monosaccharide amine and 3-nitro-2-phenyl-2H-chromene based inhibitors of glucose kinases
US11555047B2 (en) 2019-10-31 2023-01-17 University Of South Carolina One-step synthesis of phosphate-based inhibitors and applications thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT879056E (pt) * 1996-01-23 2002-10-31 Ribapharm Inc Modulacao da expressao das citocinas th1/th2 atraves de ribavirina em linfocitos t activados
JP4305662B2 (ja) * 1996-09-30 2009-07-29 大塚製薬株式会社 サイトカイン産生抑制剤及び接着抑制剤
AU738170B2 (en) * 1996-10-16 2001-09-13 Icn Pharmaceuticals, Inc. Monocyclic L-nucleosides, analogs and uses thereof
KR20010021789A (ko) 1997-08-04 2001-03-15 야스이 쇼사꾸 촉매 및 방향족 카보네이트의 제조방법
IT1296985B1 (it) * 1997-12-19 1999-08-03 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
CA2332946A1 (en) 1998-05-22 1999-12-02 Welfide Corporation Hydroxamic acid derivative and pharmaceutical use thereof
US7157092B1 (en) * 1998-06-30 2007-01-02 Om Pharma Acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same
US6831069B2 (en) 1999-08-27 2004-12-14 Ribapharm Inc. Pyrrolo[2,3-d]pyrimidine nucleoside analogs
AU1581400A (en) * 1999-12-22 2001-07-03 Om Pharma Acyl pseudopeptides bearing a functionalised auxiliary spacer
AU2001234582A1 (en) * 2000-01-25 2001-08-14 Nuvelo, Inc. Methods and materials relating to preadipocyte factor-1-like (pref-1-like) polypeptides and polynucleotides
JP2001316260A (ja) * 2000-02-29 2001-11-13 Meiji Milk Prod Co Ltd カバラクトン類を有効成分とするＴＮＦ−α産生抑制剤
DE20220947U1 (de) * 2001-02-28 2004-09-30 Ribapharm, Inc., Costa Mesa Pyrrolo2,3-dpyrimidin-Nucleosidanaloga
RU2190422C1 (ru) * 2001-04-25 2002-10-10 Кожемякин Леонид Андреевич Аэрозоль для ингаляций фармацевтической композиции глутовент и способ лечения с его использованием
JP4902913B2 (ja) * 2001-07-11 2012-03-21 森下仁丹株式会社 ＴＮＦ−α産生抑制剤
JP2004107220A (ja) * 2002-09-13 2004-04-08 Mitsubishi Pharma Corp ＴＮＦ−α産生抑制剤
JP2004256403A (ja) * 2003-02-25 2004-09-16 Kyowa Hakko Kogyo Co Ltd ＴＮＦ−α産生抑制剤
EP1602655A4 (en) * 2003-03-07 2010-06-09 Kowa Co benzofuran
CA2645053A1 (en) 2006-03-09 2007-09-13 Om Pharma Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines

Also Published As

Publication number Publication date
AU2007222135A1 (en) 2007-09-13
RU2008139985A (ru) 2010-04-20
WO2007102081A3 (en) 2009-04-23
WO2007102081A2 (en) 2007-09-13
AU2007222135B2 (en) 2012-02-02
CA2645053A1 (en) 2007-09-13
BRPI0708363A2 (pt) 2011-05-24
JP2009529523A (ja) 2009-08-20
US20140086960A1 (en) 2014-03-27
NO20084195L (no) 2008-10-07
RU2498813C2 (ru) 2013-11-20
US7915240B2 (en) 2011-03-29
KR20080105048A (ko) 2008-12-03
IL192837A (en) 2013-12-31
US20090054378A1 (en) 2009-02-26
CN101511379A (zh) 2009-08-19
US20120178721A1 (en) 2012-07-12
EP2051728A2 (en) 2009-04-29
EP2051728A4 (en) 2010-03-31
ZA200806266B (en) 2010-05-26
MX2008011360A (es) 2009-03-03
US8618080B2 (en) 2013-12-31

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