JP5290205B2 - 吸入器 - Google Patents

吸入器 Download PDF

Info

Publication number
JP5290205B2
JP5290205B2 JP2009551858A JP2009551858A JP5290205B2 JP 5290205 B2 JP5290205 B2 JP 5290205B2 JP 2009551858 A JP2009551858 A JP 2009551858A JP 2009551858 A JP2009551858 A JP 2009551858A JP 5290205 B2 JP5290205 B2 JP 5290205B2
Authority
JP
Japan
Prior art keywords
container
drug
inhaler
side wall
inhaler according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2009551858A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010519973A5 (enExample
JP2010519973A (ja
Inventor
クリクサノヴ,レオ,ビー.
グマステ,アナンド,ブイ.
Original Assignee
マイクロドース セラピューテクス,インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マイクロドース セラピューテクス,インコーポレイテッド filed Critical マイクロドース セラピューテクス,インコーポレイテッド
Publication of JP2010519973A publication Critical patent/JP2010519973A/ja
Publication of JP2010519973A5 publication Critical patent/JP2010519973A5/ja
Application granted granted Critical
Publication of JP5290205B2 publication Critical patent/JP5290205B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/001Details of inhalators; Constructional features thereof with means for agitating the medicament using ultrasonic means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043Non-destructive separation of the package, e.g. peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0066Inhalators with dosage or measuring devices with means for varying the dose size
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8268Fuel storage cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2009551858A 2007-02-28 2008-02-28 吸入器 Expired - Fee Related JP5290205B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/680,084 2007-02-28
US11/680,084 US8196576B2 (en) 2007-02-28 2007-02-28 Inhaler
PCT/US2008/055354 WO2008106616A2 (en) 2007-02-28 2008-02-28 Inhaler

Publications (3)

Publication Number Publication Date
JP2010519973A JP2010519973A (ja) 2010-06-10
JP2010519973A5 JP2010519973A5 (enExample) 2011-04-21
JP5290205B2 true JP5290205B2 (ja) 2013-09-18

Family

ID=39714478

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009551858A Expired - Fee Related JP5290205B2 (ja) 2007-02-28 2008-02-28 吸入器

Country Status (21)

Country Link
US (1) US8196576B2 (enExample)
EP (1) EP2114498B1 (enExample)
JP (1) JP5290205B2 (enExample)
KR (1) KR20090114436A (enExample)
CN (1) CN101674858B (enExample)
AU (1) AU2008221355B2 (enExample)
BR (1) BRPI0807697A2 (enExample)
CA (1) CA2679656A1 (enExample)
CY (1) CY1115499T1 (enExample)
DK (1) DK2114498T3 (enExample)
ES (1) ES2496975T3 (enExample)
HR (1) HRP20140774T1 (enExample)
IL (1) IL200565A (enExample)
MX (1) MX2009009138A (enExample)
NZ (1) NZ579264A (enExample)
PL (1) PL2114498T3 (enExample)
PT (1) PT2114498E (enExample)
RU (1) RU2488411C2 (enExample)
SI (1) SI2114498T1 (enExample)
WO (1) WO2008106616A2 (enExample)
ZA (1) ZA200905959B (enExample)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
US8528544B2 (en) * 2007-05-30 2013-09-10 Canon Kabushiki Kaisha Inhaler
CN103252007B (zh) 2008-06-13 2016-06-22 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US9205240B2 (en) 2008-12-15 2015-12-08 Profibrix B.V. Powder delivery device
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010122103A1 (en) * 2009-04-23 2010-10-28 Nycomed Gmbh Improved apparatus for the aerosolization of large volumes of dry powder
US8985101B2 (en) 2009-05-21 2015-03-24 Microdose Therapeutx, Inc. Method and device for clamping a blister within a dry powder inhaler
MY159925A (en) * 2009-05-21 2017-02-15 Microdose Therapeutx Inc Rotary cassette system for dry powder inhaler
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
US20130255678A1 (en) 2009-07-01 2013-10-03 Microdose Therapeutx, Inc. Nebulizer for infants and respiratory compromised patients
US20110000481A1 (en) * 2009-07-01 2011-01-06 Anand Gumaste Nebulizer for infants and respiratory compromised patients
US9180263B2 (en) * 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device
EP2277576A1 (en) * 2009-07-24 2011-01-26 Vectura Delivery Devices Limited Inhaler
EP2470167A4 (en) * 2009-08-27 2013-08-14 Stc Unm METHOD AND SYSTEM FOR DOSING AND COATING INHALATION POWDER ON SUPPORT PARTICLE
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CA2779488A1 (en) 2009-11-12 2011-05-19 Stc.Unm Dry powder inhaler with flutter dispersion member
CN105381524A (zh) 2010-01-05 2016-03-09 微剂量治疗技术公司 吸入设备和方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
GB201021881D0 (en) 2010-12-23 2011-02-02 Profibrix Bv Powder delivery device
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
EP2606780A1 (en) * 2011-12-22 2013-06-26 Koninklijke Philips Electronics N.V. An apparatus for, and method of, mixing a power in a liquid
US9854839B2 (en) 2012-01-31 2018-01-02 Altria Client Services Llc Electronic vaping device and method
US10463815B2 (en) * 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
KR101313993B1 (ko) * 2012-07-24 2013-10-01 한국화학연구원 약물 흡입 장치
KR101373981B1 (ko) * 2012-07-24 2014-03-12 한국화학연구원 약물 흡입 장치
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
GB201312263D0 (en) 2013-07-09 2013-08-21 The Technology Partnership Plc Separable membrane improvements
CN105451716A (zh) 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
KR101458584B1 (ko) * 2014-04-03 2014-11-07 렙메디케어주식회사 흡입용 감압 밸브 및 이를 이용한 의료용 흡입 장치
CA2951966C (en) * 2014-07-07 2021-03-16 Microdose Therapeutx, Inc. Inhalation device
JP6615860B2 (ja) * 2014-07-23 2019-12-04 マイクロドース セラピューテクス,インコーポレイテッド 乾燥粉末噴霧器
WO2016014153A1 (en) * 2014-07-23 2016-01-28 Microdose Therapeutx, Inc. Dry powder nebulizer
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
JP6653324B2 (ja) 2014-10-16 2020-02-26 テバ ブランデッド ファーマシューティカル プロダクツ アール アンド ディー インコーポレイテッド 乾燥粉末製剤
CN107106515A (zh) 2014-10-16 2017-08-29 梯瓦优质制药产品研发股份有限公司 可吸入的配制剂
EP3244851B1 (en) 2015-01-12 2024-10-16 Bausch + Lomb Ireland Limited Micro-droplet delivery device
KR20170135862A (ko) 2015-04-10 2017-12-08 켄달리온 테라퓨틱스 인코포레이티드 교체 가능한 앰플을 갖는 압전 디스펜서
KR102641134B1 (ko) * 2015-04-15 2024-02-28 필립모리스 프로덕츠 에스.에이. 흡입 디바이스를 위한 향료 요소
JP2019516485A (ja) 2016-05-19 2019-06-20 マンカインド コーポレイション 吸入を検出および監視するための機器、システム、および方法
WO2018071427A1 (en) * 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
EP3525855A4 (en) * 2016-10-11 2020-06-17 MicroDose Therapeutx, Inc. INHALATOR AND METHOD FOR USE THEREOF
WO2018071423A1 (en) * 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
KR102412086B1 (ko) 2017-01-20 2022-06-22 켄달리온 테라퓨틱스 인코포레이티드 압전 유체 분배기
CN107559270B (zh) * 2017-09-08 2023-11-14 浙江大学 合成射流平板湍流减阻装置
WO2019060604A1 (en) 2017-09-20 2019-03-28 Teva Branded Pharmaceutical Products R&D, Inc. INHALABLE MEDICINE
CA3077475A1 (en) * 2017-10-04 2019-04-11 Pneuma Respiratory, Inc. Electronic breath actuated in-line droplet delivery device and methods of use
CN111712219A (zh) 2017-12-08 2020-09-25 科达莱昂治疗公司 流体递送对准系统
US20190314198A1 (en) 2018-04-12 2019-10-17 Kedalion Therapeutics, Inc. Topical Ocular Delivery Methods and Devices for Use in the Same
US12350194B1 (en) 2018-04-12 2025-07-08 Bausch + Lomb Ireland Limited Topical ocular delivery of fluids with controlled mass dosing and wireless communication
EP3817696B8 (en) 2018-07-03 2024-12-11 Bausch + Lomb Ireland Limited Topical ocular delivery devices
US11415491B2 (en) * 2018-09-27 2022-08-16 Apple Inc. Pumping mechanism for gas sensors
US12097145B2 (en) 2019-03-06 2024-09-24 Bausch + Lomb Ireland Limited Vented multi-dose ocular fluid delivery system
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
WO2021212038A1 (en) 2020-04-17 2021-10-21 Kedalion Therapeutics, Inc. Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US11925577B2 (en) 2020-04-17 2024-03-12 Bausch + Lomb Ireland Limted Hydrodynamically actuated preservative free dispensing system
US12290472B2 (en) 2020-04-17 2025-05-06 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
KR102636221B1 (ko) * 2021-12-30 2024-02-14 주식회사 케이티앤지 추진체를 포함하는 파우더 흡입 장치
KR20250038748A (ko) 2022-07-18 2025-03-19 뉴마 레스퍼러토리 인코포레이티드 작은 스텝 크기 및 고해상도 에어로졸 생성 시스템 및 방법
CN120078994B (zh) * 2025-05-08 2025-07-08 四川省医学科学院·四川省人民医院 一种具有内置口含器分散单元的干粉药剂吸入器

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4094317A (en) * 1976-06-11 1978-06-13 Wasnich Richard D Nebulization system
IT1228460B (it) * 1989-02-23 1991-06-19 Phidea S R L Inalatore monouso con capsula pre-forata
DE69327733T2 (de) * 1992-10-16 2000-08-10 Sheiman Ultrasonic Research Foundation Pty. Ltd., Sydney Ultraschall-vernebelungsvorrichtung
US5727546A (en) * 1993-08-18 1998-03-17 Fisons Plc Powder inhaler with breath flow regulation valve
US5694920A (en) 1996-01-25 1997-12-09 Abrams; Andrew L. Inhalation device
US6026809A (en) 1996-01-25 2000-02-22 Microdose Technologies, Inc. Inhalation device
US6152130A (en) * 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
US6142146A (en) * 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
JP2000116783A (ja) * 1998-10-14 2000-04-25 Sumitomo Bakelite Co Ltd 薬剤投与器
US8820316B2 (en) * 2000-02-11 2014-09-02 Respironics Respiratory Drug Delivery (Uk) Ltd Drug delivery apparatus
US7080644B2 (en) * 2000-06-28 2006-07-25 Microdose Technologies, Inc. Packaging and delivery of pharmaceuticals and drugs
JP4675566B2 (ja) * 2002-01-25 2011-04-27 パナソニックエコシステムズ株式会社 吸入器
SE524957C2 (sv) * 2002-04-12 2004-11-02 Microdrug Ag Förfarande för uppdelning och fördelning i luft av torrt pulvermedikament
SE524990C2 (sv) * 2002-04-12 2004-11-09 Microdrug Ag Preparation av terapeutiskt torrt pulver samt förfarande för uppdelning och spridning i luft av medicinskt pulver
EP1468748A1 (en) * 2003-04-15 2004-10-20 Microflow Engineering SA Low-cost liquid droplet spray device and nozzle body
US8545463B2 (en) * 2003-05-20 2013-10-01 Optimyst Systems Inc. Ophthalmic fluid reservoir assembly for use with an ophthalmic fluid delivery device
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
WO2005076872A2 (en) * 2004-02-06 2005-08-25 Microdose Technologies, Inc. A blister pack for use with an inhalation device
CN100589849C (zh) * 2004-02-24 2010-02-17 微计量技术有限公司 基于合成射流的药物输送方法和装置
GB0420513D0 (en) * 2004-09-15 2004-10-20 Optinose As Powder delivery devices
UA27570U (en) 2007-05-30 2007-11-12 Lviv Polytekhnika Nat Universi Temperature transducer

Also Published As

Publication number Publication date
DK2114498T3 (da) 2014-09-01
CA2679656A1 (en) 2008-09-04
IL200565A (en) 2013-08-29
KR20090114436A (ko) 2009-11-03
US20080202514A1 (en) 2008-08-28
NZ579264A (en) 2011-06-30
BRPI0807697A2 (pt) 2014-05-27
CN101674858B (zh) 2013-07-03
RU2009135772A (ru) 2011-04-10
CN101674858A (zh) 2010-03-17
AU2008221355B2 (en) 2012-07-12
US8196576B2 (en) 2012-06-12
JP2010519973A (ja) 2010-06-10
WO2008106616A2 (en) 2008-09-04
EP2114498A2 (en) 2009-11-11
PT2114498E (pt) 2014-09-04
AU2008221355A1 (en) 2008-09-04
MX2009009138A (es) 2009-10-19
ES2496975T3 (es) 2014-09-22
SI2114498T1 (sl) 2014-10-30
PL2114498T3 (pl) 2015-02-27
EP2114498A4 (en) 2010-08-25
CY1115499T1 (el) 2017-01-04
ZA200905959B (en) 2010-11-24
IL200565A0 (en) 2010-05-17
WO2008106616A3 (en) 2008-10-30
RU2488411C2 (ru) 2013-07-27
HRP20140774T1 (en) 2014-11-07
EP2114498B1 (en) 2014-07-30

Similar Documents

Publication Publication Date Title
JP5290205B2 (ja) 吸入器
CA2554136C (en) Synthetic jet based medicament delivery method and apparatus
TWI524907B (zh) 吸入裝置及在吸入裝置中提供反饋控制的方法
HK1142286A (en) Inhaler
HK1142286B (en) Inhaler
HK1147705B (en) Inhalation device
HK1097782B (en) Synthetic jet based medicament delivery method and apparatus

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110225

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110301

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20120809

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120814

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121114

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20130604

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20130605

R150 Certificate of patent or registration of utility model

Ref document number: 5290205

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees