JP5249226B2 - 凝固第ＩＸａ因子インヒビターとしての使用のためのイソセリン誘導体 - Google Patents

凝固第ＩＸａ因子インヒビターとしての使用のためのイソセリン誘導体 Download PDF

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JP5249226B2
JP5249226B2 JP2009527720A JP2009527720A JP5249226B2 JP 5249226 B2 JP5249226 B2 JP 5249226B2 JP 2009527720 A JP2009527720 A JP 2009527720A JP 2009527720 A JP2009527720 A JP 2009527720A JP 5249226 B2 JP5249226 B2 JP 5249226B2
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ylcarbamoyl
hydroxy
amino
phenylethyl
benzimidazol
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JP2010503625A5 (enExample
JP2010503625A (ja
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ヘニング・シュタインハーゲン
マルクス・フォールマン
ヨッヘン・ゲルリツァー
ヘルマン・シュロイダー
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Sanofi SA
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    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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JP2009527720A 2006-09-13 2007-08-31 凝固第ＩＸａ因子インヒビターとしての使用のためのイソセリン誘導体 Expired - Fee Related JP5249226B2 (ja)

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DE102006042926 2006-09-13
DE102006042926.5 2006-09-13
PCT/EP2007/007613 WO2008031509A1 (de) 2006-09-13 2007-08-31 Isoserinderivate als inhibitoren des koagulationsfaktors ixa

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WO2003078448A1 (en) 2002-03-13 2003-09-25 Signum Biosciences, Inc. Modulation of protein methylation and phosphoprotein phosphate
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
WO2006084033A1 (en) 2005-02-03 2006-08-10 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US8383636B2 (en) * 2006-09-07 2013-02-26 Industrial Research Limited Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase
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