AR063708A1 - Derivados de isoserina, un proceso para su preparacion y su empleo en la produccion de un medicamento para el tratamiento o profilaxis de enfermedades mediadas por la inhibicion del factor ixa de la coagulacion sanguinea. - Google Patents

Derivados de isoserina, un proceso para su preparacion y su empleo en la produccion de un medicamento para el tratamiento o profilaxis de enfermedades mediadas por la inhibicion del factor ixa de la coagulacion sanguinea.

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Publication number
AR063708A1
AR063708A1 ARP070104012A ARP070104012A AR063708A1 AR 063708 A1 AR063708 A1 AR 063708A1 AR P070104012 A ARP070104012 A AR P070104012A AR P070104012 A ARP070104012 A AR P070104012A AR 063708 A1 AR063708 A1 AR 063708A1
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AR
Argentina
Prior art keywords
trisubstituted
mono
aryl
het
substituted
Prior art date
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ARP070104012A
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English (en)
Spanish (es)
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Sanofi Aventis
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Publication of AR063708A1 publication Critical patent/AR063708A1/es

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    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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ARP070104012A 2006-09-13 2007-09-11 Derivados de isoserina, un proceso para su preparacion y su empleo en la produccion de un medicamento para el tratamiento o profilaxis de enfermedades mediadas por la inhibicion del factor ixa de la coagulacion sanguinea. AR063708A1 (es)

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AR063708A1 true AR063708A1 (es) 2009-02-11

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US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
WO2006084033A1 (en) 2005-02-03 2006-08-10 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US8383636B2 (en) * 2006-09-07 2013-02-26 Industrial Research Limited Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase
CN102014897B (zh) 2008-04-21 2015-08-05 西格纳姆生物科学公司 化合物、组合物和其制备方法
AU2009322342A1 (en) 2008-12-05 2011-06-30 Merck Sharp & Dohme Corp. Morpholinone compounds as factor IXa inhibitors
EP2473491B1 (en) * 2009-08-31 2013-07-17 Mochida Pharmaceutical Co., Ltd. Morpholinone compounds as factor ixa inhibitors
WO2015160636A1 (en) 2014-04-16 2015-10-22 Merck Sharp & Dohme Corp. Factor ixa inhibitors
CN109627218B (zh) * 2018-11-27 2022-03-29 深圳市龙华区中心医院 一种抗凝小分子化合物及其应用和包含其的药物

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DE4238260A1 (de) 1992-11-12 1994-05-19 Basf Ag Substituierte ortho-Ethenylphenylessigsäurederivate
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EP2069289B1 (de) 2013-10-02
UY30585A1 (es) 2008-05-02
MY150745A (en) 2014-02-28
JP5249226B2 (ja) 2013-07-31
NO20091110L (no) 2009-06-09
ZA200900807B (en) 2009-11-25
CA2663544A1 (en) 2008-03-20
CL2007002652A1 (es) 2008-02-08
KR20090050081A (ko) 2009-05-19
CN101516834A (zh) 2009-08-26
TWI394570B (zh) 2013-05-01
SG174080A1 (en) 2011-09-29
RU2446157C2 (ru) 2012-03-27
NZ575603A (en) 2011-03-31
RU2009113602A (ru) 2010-10-20
CN101516834B (zh) 2013-04-03
MX2009002047A (es) 2009-03-06
JP2010503625A (ja) 2010-02-04
BRPI0716991A2 (pt) 2013-10-08
IL197504A (en) 2013-06-27
MA30707B1 (fr) 2009-09-01
EP2069289A1 (de) 2009-06-17
AU2007297013A1 (en) 2008-03-20
AU2007297013B2 (en) 2012-05-31
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US8097758B2 (en) 2012-01-17

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