JP5218443B2 - マイクロチップ及びマイクロチップの製造方法 - Google Patents

マイクロチップ及びマイクロチップの製造方法 Download PDF

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Publication number
JP5218443B2
JP5218443B2 JP2010028241A JP2010028241A JP5218443B2 JP 5218443 B2 JP5218443 B2 JP 5218443B2 JP 2010028241 A JP2010028241 A JP 2010028241A JP 2010028241 A JP2010028241 A JP 2010028241A JP 5218443 B2 JP5218443 B2 JP 5218443B2
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Japan
Prior art keywords
substrate layer
microchip
flow path
well
sample solution
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Application number
JP2010028241A
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English (en)
Japanese (ja)
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JP2011163984A5 (enExample
JP2011163984A (ja
Inventor
英俊 渡辺
雄司 瀬川
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Sony Corp
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Sony Corp
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Filing date
Publication date
Priority to JP2010028241A priority Critical patent/JP5218443B2/ja
Application filed by Sony Corp filed Critical Sony Corp
Priority to CN201180008428.5A priority patent/CN102740977B/zh
Priority to US13/577,391 priority patent/US9132424B2/en
Priority to PCT/JP2011/000535 priority patent/WO2011099246A1/en
Priority to EP11704682.1A priority patent/EP2533902B1/en
Priority to SG2012054870A priority patent/SG182707A1/en
Publication of JP2011163984A publication Critical patent/JP2011163984A/ja
Publication of JP2011163984A5 publication Critical patent/JP2011163984A5/ja
Application granted granted Critical
Publication of JP5218443B2 publication Critical patent/JP5218443B2/ja
Priority to US14/851,139 priority patent/US9597683B2/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
JP2010028241A 2010-02-10 2010-02-10 マイクロチップ及びマイクロチップの製造方法 Active JP5218443B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2010028241A JP5218443B2 (ja) 2010-02-10 2010-02-10 マイクロチップ及びマイクロチップの製造方法
US13/577,391 US9132424B2 (en) 2010-02-10 2011-02-01 Microchip and method of producing microchip
PCT/JP2011/000535 WO2011099246A1 (en) 2010-02-10 2011-02-01 Microchip and method of producing microchip
EP11704682.1A EP2533902B1 (en) 2010-02-10 2011-02-01 Microchip and method of producing microchip
CN201180008428.5A CN102740977B (zh) 2010-02-10 2011-02-01 微芯片和微芯片制造方法
SG2012054870A SG182707A1 (en) 2010-02-10 2011-02-01 Microchip and method of producing microchip
US14/851,139 US9597683B2 (en) 2010-02-10 2015-09-11 Microchip and method of producing microchip

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010028241A JP5218443B2 (ja) 2010-02-10 2010-02-10 マイクロチップ及びマイクロチップの製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013036111A Division JP5708683B2 (ja) 2013-02-26 2013-02-26 マイクロチップ及びマイクロチップの製造方法

Publications (3)

Publication Number Publication Date
JP2011163984A JP2011163984A (ja) 2011-08-25
JP2011163984A5 JP2011163984A5 (enExample) 2012-09-20
JP5218443B2 true JP5218443B2 (ja) 2013-06-26

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JP2010028241A Active JP5218443B2 (ja) 2010-02-10 2010-02-10 マイクロチップ及びマイクロチップの製造方法

Country Status (6)

Country Link
US (2) US9132424B2 (enExample)
EP (1) EP2533902B1 (enExample)
JP (1) JP5218443B2 (enExample)
CN (1) CN102740977B (enExample)
SG (1) SG182707A1 (enExample)
WO (1) WO2011099246A1 (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN111013676A (zh) * 2019-12-17 2020-04-17 江苏圣极基因科技有限公司 一种液滴制备方法及微流控芯片

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JP5218443B2 (ja) * 2010-02-10 2013-06-26 ソニー株式会社 マイクロチップ及びマイクロチップの製造方法
JP2013130396A (ja) * 2011-12-20 2013-07-04 Sony Corp マイクロチップ
JP6197263B2 (ja) * 2012-02-06 2017-09-20 ソニー株式会社 マイクロチップ
CN104303062A (zh) * 2012-05-24 2015-01-21 索尼公司 微芯片
US20150239217A1 (en) * 2012-07-09 2015-08-27 Sony Corporation Microchip and method for manufacturing the same
CN104949789B (zh) * 2014-03-26 2017-10-31 中国科学院理化技术研究所 一种微流道压力传感器
GB201418899D0 (en) 2014-10-23 2014-12-10 Univ Hull System for radiopharmaceutical production
GB201418897D0 (en) 2014-10-23 2014-12-10 Univ Hull Methods and apparatus for the analysis of compounds
GB201418893D0 (en) 2014-10-23 2014-12-10 Univ Hull Monolithic body
CN107249742B (zh) * 2014-12-08 2019-12-06 伯克利之光生命科技公司 微流体装置中定向流动的致动微流体结构及使用它的方法
JP6466774B2 (ja) * 2015-04-30 2019-02-06 栄研化学株式会社 マイクロチップ
CN105715865B (zh) * 2016-03-24 2018-04-27 中国科学院理化技术研究所 电磁微阀装置
JP6394651B2 (ja) * 2016-07-15 2018-09-26 ウシオ電機株式会社 基板の貼り合わせ方法およびマイクロチップの製造方法
WO2018109829A1 (ja) * 2016-12-13 2018-06-21 栄研化学株式会社 マイクロチップ
JP2017203776A (ja) * 2017-06-21 2017-11-16 ソニー株式会社 マイクロチップ
JP7167434B2 (ja) * 2017-12-13 2022-11-09 株式会社ニコン 流体デバイス、リザーバー供給システムおよび流路供給システム
USD878622S1 (en) * 2018-04-07 2020-03-17 Precision Nanosystems Inc. Microfluidic chip
JP6658857B2 (ja) * 2018-12-27 2020-03-04 ソニー株式会社 マイクロチップ
WO2020183938A1 (ja) * 2019-03-08 2020-09-17 株式会社フコク マイクロ流路チップ
CN119657250B (zh) * 2025-02-20 2025-05-27 至美时代生物智能科技(北京)有限公司 一种储液式微流控芯片及其工作方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111013676A (zh) * 2019-12-17 2020-04-17 江苏圣极基因科技有限公司 一种液滴制备方法及微流控芯片

Also Published As

Publication number Publication date
US20160001287A1 (en) 2016-01-07
EP2533902B1 (en) 2019-04-03
CN102740977B (zh) 2016-05-04
CN102740977A (zh) 2012-10-17
US9132424B2 (en) 2015-09-15
WO2011099246A1 (en) 2011-08-18
US20120301372A1 (en) 2012-11-29
SG182707A1 (en) 2012-08-30
JP2011163984A (ja) 2011-08-25
US9597683B2 (en) 2017-03-21
EP2533902A1 (en) 2012-12-19

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