JP5206405B2 - イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 - Google Patents

イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 Download PDF

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JP5206405B2
JP5206405B2 JP2008502953A JP2008502953A JP5206405B2 JP 5206405 B2 JP5206405 B2 JP 5206405B2 JP 2008502953 A JP2008502953 A JP 2008502953A JP 2008502953 A JP2008502953 A JP 2008502953A JP 5206405 B2 JP5206405 B2 JP 5206405B2
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group
alkyl
aryl
optionally substituted
compound
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JP2008533198A (ja
JP2008533198A5 (enExample
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リ，ケン・チ・リク
サン，エリック・ティー
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Lite Strategy Inc
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Mei Pharma Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
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    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
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  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
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  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
JP2008502953A 2005-03-21 2006-03-20 イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 Expired - Fee Related JP5206405B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66326505P 2005-03-21 2005-03-21
US60/663,265 2005-03-21
US75954406P 2006-01-18 2006-01-18
US60/759,544 2006-01-18
PCT/SG2006/000064 WO2006101455A1 (en) 2005-03-21 2006-03-20 Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications

Publications (3)

Publication Number Publication Date
JP2008533198A JP2008533198A (ja) 2008-08-21
JP2008533198A5 JP2008533198A5 (enExample) 2009-05-07
JP5206405B2 true JP5206405B2 (ja) 2013-06-12

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JP2008502953A Expired - Fee Related JP5206405B2 (ja) 2005-03-21 2006-03-20 イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途

Country Status (12)

Country Link
EP (1) EP1863811B1 (enExample)
JP (1) JP5206405B2 (enExample)
KR (1) KR101300831B1 (enExample)
CN (1) CN101218238B (enExample)
AR (1) AR056187A1 (enExample)
AU (1) AU2006225355B2 (enExample)
CA (1) CA2602328C (enExample)
ES (1) ES2470766T3 (enExample)
MX (1) MX2007011710A (enExample)
MY (1) MY147647A (enExample)
TW (1) TW200714600A (enExample)
WO (1) WO2006101455A1 (enExample)

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WO2008029152A2 (en) * 2006-09-08 2008-03-13 Summit Corporation Plc Treatment of duchenne muscular dystrophy
EP2064211B1 (en) * 2006-09-20 2015-11-11 MEI Pharma, Inc. Imidazo[1,2-a]pyridine hydroxymate compounds that are inhibitors of histone deacetylase
EA201300152A1 (ru) 2006-11-27 2013-07-30 Х. Лундбекк А/С Гетероариламидные производные
WO2008068392A1 (fr) * 2006-12-07 2008-06-12 Commissariat A L'energie Atomique Nouveaux derives fluorophores imidazo [1,2-a] pyridin-3-yl-amine et leur procede de preparation
EP2155744A1 (en) 2007-04-10 2010-02-24 Lundbeck, H., A/S Heteroaryl amide analogues as p2x7 antagonists
WO2008134553A1 (en) * 2007-04-26 2008-11-06 Xenon Pharmaceuticals Inc. Methods of using bicyclic compounds in treating sodium channel-mediated diseases
CN101855222A (zh) * 2007-05-10 2010-10-06 通用电气健康护理有限公司 对大麻素cb2受体具有活性的咪唑并(1,2-a)吡啶和相关化合物
EP2180893B1 (en) * 2007-08-09 2014-11-12 Urifer Ltd Pharmaceutical compositions and methods for the treatment of cancer
DE102007040336A1 (de) 2007-08-27 2009-03-05 Johann Wolfgang Goethe-Universität Frankfurt am Main Neue Inhibitoren der 5-Lipoxygenase und deren Verwendungen
JP2011502133A (ja) * 2007-11-02 2011-01-20 メシルジーン インコーポレイテッド ヒストンデアセチラーゼの阻害剤
WO2009143156A2 (en) * 2008-05-19 2009-11-26 Sepracor Inc. IMIDAZO[1,2-a]PYRIDINE COMPOUNDS
WO2010032195A1 (en) 2008-09-16 2010-03-25 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
WO2010043953A2 (en) * 2008-10-15 2010-04-22 Orchid Research Laboratories Ltd. Novel bridged cyclic compounds as histone deacetylase inhibitors
AU2011285708B2 (en) * 2010-08-03 2014-07-24 The Regents Of The University Of California Compounds and compositions for mitigating tissue damage and lethality
US9000186B2 (en) 2011-02-01 2015-04-07 Kyowa Hakko Kirin Co., Ltd. Ring-fused heterocyclic derivative
US20140221354A1 (en) * 2011-03-31 2014-08-07 Emblem Technology Transfer Gmbh IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY
UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
CN104619707A (zh) * 2012-07-31 2015-05-13 协和发酵麒麟株式会社 稠环杂环化合物
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
SI2991984T1 (sl) * 2013-04-30 2017-05-31 F. Hoffmann-La Roche Ag Povezovanje pirazolovih amidov, katalizirano s paladijem
SG11201509650YA (en) * 2013-05-24 2015-12-30 Iomet Pharma Ltd Slc2a transporter inhibitors
CN105358151B (zh) 2013-06-25 2019-04-12 豪夫迈·罗氏有限公司 用于治疗脊髓性肌萎缩的化合物
WO2015058106A1 (en) 2013-10-18 2015-04-23 The General Hospital Corporation Imaging histone deacetylases with a radiotracer using positron emission tomography
US10723705B2 (en) 2015-08-14 2020-07-28 Incyte Corporation Heterocyclic compounds and uses thereof
WO2018048261A1 (ko) * 2016-09-08 2018-03-15 가천대학교 산학협력단 신규 스피로퀴논 유도체 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 신경계 질환의 예방 또는 치료용 약학적 조성물
EP4019607B1 (en) 2020-12-22 2024-05-15 Essilor International Electrochromic compounds and optical articles containing them
CN113321651B (zh) * 2021-06-22 2022-06-14 四川省医学科学院·四川省人民医院 吡唑并吡啶异羟肟酸类化合物、其制备方法及其应用

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EP1863811A4 (en) 2008-11-12
CN101218238B (zh) 2011-10-26
CA2602328A1 (en) 2006-09-28
EP1863811B1 (en) 2014-03-12
CA2602328C (en) 2014-07-29
EP1863811A1 (en) 2007-12-12
MY147647A (en) 2012-12-31
MX2007011710A (es) 2007-11-20
JP2008533198A (ja) 2008-08-21
ES2470766T3 (es) 2014-06-24
AU2006225355B2 (en) 2010-12-09
KR101300831B1 (ko) 2013-08-30
CN101218238A (zh) 2008-07-09
AU2006225355A1 (en) 2006-09-28
WO2006101455A1 (en) 2006-09-28
AR056187A1 (es) 2007-09-26
KR20080005207A (ko) 2008-01-10
TW200714600A (en) 2007-04-16

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