JP5206405B2 - イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 - Google Patents

イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 Download PDF

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JP5206405B2
JP5206405B2 JP2008502953A JP2008502953A JP5206405B2 JP 5206405 B2 JP5206405 B2 JP 5206405B2 JP 2008502953 A JP2008502953 A JP 2008502953A JP 2008502953 A JP2008502953 A JP 2008502953A JP 5206405 B2 JP5206405 B2 JP 5206405B2
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group
alkyl
aryl
optionally substituted
compound
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JP2008533198A (ja
JP2008533198A5 (cg-RX-API-DMAC10.html
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リ，ケン・チ・リク
サン，エリック・ティー
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Lite Strategy Inc
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Mei Pharma Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
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    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
JP2008502953A 2005-03-21 2006-03-20 イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 Expired - Fee Related JP5206405B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66326505P 2005-03-21 2005-03-21
US60/663,265 2005-03-21
US75954406P 2006-01-18 2006-01-18
US60/759,544 2006-01-18
PCT/SG2006/000064 WO2006101455A1 (en) 2005-03-21 2006-03-20 Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications

Publications (3)

Publication Number Publication Date
JP2008533198A JP2008533198A (ja) 2008-08-21
JP2008533198A5 JP2008533198A5 (cg-RX-API-DMAC10.html) 2009-05-07
JP5206405B2 true JP5206405B2 (ja) 2013-06-12

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JP2008502953A Expired - Fee Related JP5206405B2 (ja) 2005-03-21 2006-03-20 イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途

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Country Link
EP (1) EP1863811B1 (cg-RX-API-DMAC10.html)
JP (1) JP5206405B2 (cg-RX-API-DMAC10.html)
KR (1) KR101300831B1 (cg-RX-API-DMAC10.html)
CN (1) CN101218238B (cg-RX-API-DMAC10.html)
AR (1) AR056187A1 (cg-RX-API-DMAC10.html)
AU (1) AU2006225355B2 (cg-RX-API-DMAC10.html)
CA (1) CA2602328C (cg-RX-API-DMAC10.html)
ES (1) ES2470766T3 (cg-RX-API-DMAC10.html)
MX (1) MX2007011710A (cg-RX-API-DMAC10.html)
MY (1) MY147647A (cg-RX-API-DMAC10.html)
TW (1) TW200714600A (cg-RX-API-DMAC10.html)
WO (1) WO2006101455A1 (cg-RX-API-DMAC10.html)

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WO2008068392A1 (fr) * 2006-12-07 2008-06-12 Commissariat A L'energie Atomique Nouveaux derives fluorophores imidazo [1,2-a] pyridin-3-yl-amine et leur procede de preparation
CN103204852A (zh) 2007-04-10 2013-07-17 H.隆德贝克有限公司 作为p2x7拮抗剂的杂芳基酰胺类似物
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DE102007040336A1 (de) 2007-08-27 2009-03-05 Johann Wolfgang Goethe-Universität Frankfurt am Main Neue Inhibitoren der 5-Lipoxygenase und deren Verwendungen
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WO2010032195A1 (en) * 2008-09-16 2010-03-25 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
US20110212943A1 (en) * 2008-10-15 2011-09-01 Orchid Research Laboratories Limited Novel bridged cyclic compounds as histone deacetylase inhibitors
CA2807230A1 (en) * 2010-08-03 2012-02-09 The Regents Of The University Of California Compounds and compositions for mitigating tissue damage and lethality
KR20140048079A (ko) 2011-02-01 2014-04-23 교와 핫꼬 기린 가부시키가이샤 축환 복소환 유도체
JP2014509616A (ja) * 2011-03-31 2014-04-21 エーエムベーエルエーエム テクノロジー トランスファー ゲーエムベーハー 治療用イミダゾ［１，２−ａ］ピリジン化合物
US8883819B2 (en) 2011-09-01 2014-11-11 Irm Llc Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
CN104619707A (zh) * 2012-07-31 2015-05-13 协和发酵麒麟株式会社 稠环杂环化合物
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
CN105164126B (zh) * 2013-04-30 2017-05-31 豪夫迈·罗氏有限公司 吡唑酰胺的Pd‑催化偶联
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CA2913785C (en) * 2013-06-25 2021-08-31 F. Hoffmann-La Roche Ag Compounds for treating spinal muscular atrophy
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EP4019607B1 (en) 2020-12-22 2024-05-15 Essilor International Electrochromic compounds and optical articles containing them
CN113321651B (zh) * 2021-06-22 2022-06-14 四川省医学科学院·四川省人民医院 吡唑并吡啶异羟肟酸类化合物、其制备方法及其应用

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KR20080005207A (ko) 2008-01-10
CA2602328A1 (en) 2006-09-28
CA2602328C (en) 2014-07-29
MY147647A (en) 2012-12-31
EP1863811B1 (en) 2014-03-12
EP1863811A4 (en) 2008-11-12
TW200714600A (en) 2007-04-16
ES2470766T3 (es) 2014-06-24
KR101300831B1 (ko) 2013-08-30
JP2008533198A (ja) 2008-08-21
EP1863811A1 (en) 2007-12-12
AU2006225355B2 (en) 2010-12-09
MX2007011710A (es) 2007-11-20
CN101218238A (zh) 2008-07-09
AR056187A1 (es) 2007-09-26
CN101218238B (zh) 2011-10-26
WO2006101455A1 (en) 2006-09-28
AU2006225355A1 (en) 2006-09-28

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