JP5205802B2 - リアルタイムｐｃｒ装置 - Google Patents

リアルタイムｐｃｒ装置 Download PDF

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Publication number
JP5205802B2
JP5205802B2 JP2007126344A JP2007126344A JP5205802B2 JP 5205802 B2 JP5205802 B2 JP 5205802B2 JP 2007126344 A JP2007126344 A JP 2007126344A JP 2007126344 A JP2007126344 A JP 2007126344A JP 5205802 B2 JP5205802 B2 JP 5205802B2
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JP
Japan
Prior art keywords
heat source
real
temperature
time pcr
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2007126344A
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English (en)
Japanese (ja)
Other versions
JP2008278810A5 (https=
JP2008278810A (ja
Inventor
俊貴 森脇
翼 世取山
雄司 瀬川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sony Corp
Original Assignee
Sony Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sony Corp filed Critical Sony Corp
Priority to JP2007126344A priority Critical patent/JP5205802B2/ja
Priority to EP08007661A priority patent/EP1994980A1/en
Priority to US12/105,722 priority patent/US8017380B2/en
Priority to CN2008100961874A priority patent/CN101302473B/zh
Publication of JP2008278810A publication Critical patent/JP2008278810A/ja
Publication of JP2008278810A5 publication Critical patent/JP2008278810A5/ja
Application granted granted Critical
Publication of JP5205802B2 publication Critical patent/JP5205802B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K7/00—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements
    • G01K7/01—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using semiconducting elements having PN junctions
    • G01K7/015—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using semiconducting elements having PN junctions using microstructures, e.g. made of silicon
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00853—Employing electrode arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2007126344A 2007-05-11 2007-05-11 リアルタイムｐｃｒ装置 Expired - Fee Related JP5205802B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2007126344A JP5205802B2 (ja) 2007-05-11 2007-05-11 リアルタイムｐｃｒ装置
EP08007661A EP1994980A1 (en) 2007-05-11 2008-04-18 Real-time PCR system
US12/105,722 US8017380B2 (en) 2007-05-11 2008-04-18 Real-time PCR system
CN2008100961874A CN101302473B (zh) 2007-05-11 2008-05-09 实时pcr系统

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007126344A JP5205802B2 (ja) 2007-05-11 2007-05-11 リアルタイムｐｃｒ装置

Publications (3)

Publication Number Publication Date
JP2008278810A JP2008278810A (ja) 2008-11-20
JP2008278810A5 JP2008278810A5 (https=) 2010-04-22
JP5205802B2 true JP5205802B2 (ja) 2013-06-05

Family

ID=39619177

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007126344A Expired - Fee Related JP5205802B2 (ja) 2007-05-11 2007-05-11 リアルタイムｐｃｒ装置

Country Status (4)

Country Link
US (1) US8017380B2 (https=)
EP (1) EP1994980A1 (https=)
JP (1) JP5205802B2 (https=)
CN (1) CN101302473B (https=)

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* Cited by examiner, † Cited by third party
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JP4458133B2 (ja) * 2007-02-27 2010-04-28 ソニー株式会社 核酸増幅装置
US9475051B2 (en) 2007-02-27 2016-10-25 Sony Corporation Nucleic acid amplifier
JP5045268B2 (ja) 2007-06-28 2012-10-10 ソニー株式会社 反応処理装置
JP5423006B2 (ja) * 2009-01-20 2014-02-19 ソニー株式会社 プライマー評価方法、プライマー評価プログラム及びリアルタイムｐｃｒ装置
JP5310373B2 (ja) * 2009-05-14 2013-10-09 ソニー株式会社 光学的検出装置
US8419273B2 (en) 2010-05-03 2013-04-16 Sharp Kabushiki Kaisha Array element for temperature sensor array circuit, temperature sensor array circuit utilizing such array element, and AM-EWOD device including such a temperature sensor array circuit
JP2012118055A (ja) * 2010-11-12 2012-06-21 Sony Corp 反応処理装置及び反応処理方法
KR101853882B1 (ko) * 2011-01-10 2018-05-02 삼성전자주식회사 생체물질 검사장치 및 그 제어방법
WO2012178210A1 (en) * 2011-06-23 2012-12-27 Anitoa Systems, Llc Apparatus for amplification of nucleic acids
US9211541B2 (en) 2011-06-24 2015-12-15 Hitachi High-Technologies Corporation Nucleic acid amplification apparatus and nucleic acid analysis apparatus
CN102533544B (zh) * 2011-12-31 2013-07-10 中山大学达安基因股份有限公司 一种电化学基因检测系统
CN102586098B (zh) * 2012-02-29 2013-11-20 北京工业大学 一种面向空间的微体积单位的实时荧光pcr工作系统
BR112014032911A2 (pt) * 2012-06-28 2017-06-27 Fluoresentric Inc dispositivo indicador químico
TWI458828B (zh) * 2012-07-18 2014-11-01 Univ Nat Pingtung Sci & Tech Droplet type high throughput thermal cycling system
AU2013202793B2 (en) 2012-07-31 2014-09-18 Gen-Probe Incorporated System, method and apparatus for automated incubation
JP6087138B2 (ja) * 2012-12-28 2017-03-01 株式会社日立ハイテクノロジーズ 遺伝子検査装置、遺伝子検査方法及びプログラム
KR101696259B1 (ko) * 2014-07-23 2017-01-13 나노바이오시스 주식회사 멀티플렉스 ｐｃｒ 칩 및 이를 포함하는 멀티플렉스 ｐｃｒ 장치
CN106328659B (zh) * 2016-08-19 2019-06-14 京东方科技集团股份有限公司 阵列基板及其制备方法、显示面板
CN107058090A (zh) * 2017-04-27 2017-08-18 滨江华康（北京）生物科技有限公司 一种实时荧光定量pcr基因扩增检测仪
CN107460121A (zh) * 2017-07-22 2017-12-12 新疆昆泰锐生物技术有限公司 一种pcr反应体系配制及进样装置及全自动pcr仪
CN107460108A (zh) * 2017-07-23 2017-12-12 新疆昆泰锐生物技术有限公司 一种连续进样的pcr反应体系配制及进样装置及pcr仪
CN107653187A (zh) * 2017-11-07 2018-02-02 安图实验仪器(郑州)有限公司 随机pcr系统
JP7157658B2 (ja) * 2018-12-27 2022-10-20 株式会社日立ハイテク 自動分析装置
JP7366247B2 (ja) 2020-04-14 2023-10-20 Ｐｈｃホールディングス株式会社 核酸検査装置および核酸検査方法
JP2024535381A (ja) 2021-09-23 2024-09-30 エヌシックス・テック、インコーポレイテッド 試料分析のための方法およびシステム
CN114672405A (zh) * 2022-03-21 2022-06-28 诺美纳瑞(广州)医疗技术有限公司 一种pcr扩增检测集成系统及其pcr反应控制方法
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device

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Also Published As

Publication number Publication date
JP2008278810A (ja) 2008-11-20
CN101302473B (zh) 2013-10-16
CN101302473A (zh) 2008-11-12
US20080280350A1 (en) 2008-11-13
US8017380B2 (en) 2011-09-13
EP1994980A1 (en) 2008-11-26

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