JP5127106B2 - ４−アルコキシシクロヘキサン−１−アミノカルボン酸エステル及びその製造法 - Google Patents

４−アルコキシシクロヘキサン−１−アミノカルボン酸エステル及びその製造法 Download PDF

Info

Publication number
JP5127106B2
JP5127106B2 JP2002507789A JP2002507789A JP5127106B2 JP 5127106 B2 JP5127106 B2 JP 5127106B2 JP 2002507789 A JP2002507789 A JP 2002507789A JP 2002507789 A JP2002507789 A JP 2002507789A JP 5127106 B2 JP5127106 B2 JP 5127106B2
Authority
JP
Japan
Prior art keywords
formula
cis
iii
trans
embedded image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2002507789A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004502678A (ja
JP2004502678A5 (enExample
Inventor
ヒムラー，トマス
フイシヤー，ライナー
ガレンカンプ，ベルント
クノプス，ハンス−ヨアヒム
ムルダー，ルベルトウス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer CropScience AG
Original Assignee
Bayer CropScience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer CropScience AG filed Critical Bayer CropScience AG
Publication of JP2004502678A publication Critical patent/JP2004502678A/ja
Publication of JP2004502678A5 publication Critical patent/JP2004502678A5/ja
Application granted granted Critical
Publication of JP5127106B2 publication Critical patent/JP5127106B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2002507789A 2000-07-05 2001-06-22 ４−アルコキシシクロヘキサン−１−アミノカルボン酸エステル及びその製造法 Expired - Lifetime JP5127106B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10032587A DE10032587A1 (de) 2000-07-05 2000-07-05 4-Alkoxy-cyclohexan-1-amino-carbonsäureester und Verfahren zu ihrer Herstellung
DE10032587.4 2000-07-05
PCT/EP2001/007115 WO2002002532A1 (de) 2000-07-05 2001-06-22 4-alkoxy-cyclohexan-1-amino-carbonsäureester und verfahren zu ihrer herstellung

Related Child Applications (3)

Application Number Title Priority Date Filing Date
JP2012057090A Division JP5805561B2 (ja) 2000-07-05 2012-03-14 ４−アルコキシ−シクロヘキサン−１−アミノ−カルボン酸
JP2012202817A Division JP5899091B2 (ja) 2000-07-05 2012-09-14 ヒダントイン誘導体
JP2012202818A Division JP5899092B2 (ja) 2000-07-05 2012-09-14 ヒダントイン誘導体の製造法

Publications (3)

Publication Number Publication Date
JP2004502678A JP2004502678A (ja) 2004-01-29
JP2004502678A5 JP2004502678A5 (enExample) 2008-08-14
JP5127106B2 true JP5127106B2 (ja) 2013-01-23

Family

ID=7647819

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2002507789A Expired - Lifetime JP5127106B2 (ja) 2000-07-05 2001-06-22 ４−アルコキシシクロヘキサン−１−アミノカルボン酸エステル及びその製造法
JP2012057090A Expired - Lifetime JP5805561B2 (ja) 2000-07-05 2012-03-14 ４−アルコキシ−シクロヘキサン−１−アミノ−カルボン酸
JP2012202817A Expired - Lifetime JP5899091B2 (ja) 2000-07-05 2012-09-14 ヒダントイン誘導体
JP2012202818A Expired - Lifetime JP5899092B2 (ja) 2000-07-05 2012-09-14 ヒダントイン誘導体の製造法
JP2014100409A Pending JP2014167018A (ja) 2000-07-05 2014-05-14 ４−アルコキシ−シクロヘキサン−１−アミノ−カルボン酸

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2012057090A Expired - Lifetime JP5805561B2 (ja) 2000-07-05 2012-03-14 ４−アルコキシ−シクロヘキサン−１−アミノ−カルボン酸
JP2012202817A Expired - Lifetime JP5899091B2 (ja) 2000-07-05 2012-09-14 ヒダントイン誘導体
JP2012202818A Expired - Lifetime JP5899092B2 (ja) 2000-07-05 2012-09-14 ヒダントイン誘導体の製造法
JP2014100409A Pending JP2014167018A (ja) 2000-07-05 2014-05-14 ４−アルコキシ−シクロヘキサン−１−アミノ−カルボン酸

Country Status (15)

Country Link
US (3) US7148377B2 (enExample)
EP (1) EP1309562B1 (enExample)
JP (5) JP5127106B2 (enExample)
KR (1) KR100758620B1 (enExample)
CN (2) CN1286820C (enExample)
AT (1) ATE394379T1 (enExample)
AU (1) AU2001272504A1 (enExample)
BR (1) BR0112245B1 (enExample)
DE (2) DE10032587A1 (enExample)
DK (1) DK1309562T3 (enExample)
ES (1) ES2305090T3 (enExample)
IL (3) IL153561A0 (enExample)
MX (1) MXPA02012889A (enExample)
WO (1) WO2002002532A1 (enExample)
ZA (1) ZA200300005B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10032587A1 (de) * 2000-07-05 2002-01-17 Bayer Ag 4-Alkoxy-cyclohexan-1-amino-carbonsäureester und Verfahren zu ihrer Herstellung
DE10213051B4 (de) * 2002-03-23 2013-03-07 Grünenthal GmbH Substituierte 4-Aminocyclohexanole
DE10231333A1 (de) * 2002-07-11 2004-01-22 Bayer Cropscience Ag Cis-Alkoxysubstituierte spirocyclische 1-H-Pyrrolidin-2,4-dion-Derivate
DE10239479A1 (de) * 2002-08-28 2004-03-04 Bayer Cropscience Ag Substituierte spirocyclische Ketoenole
DE10241062A1 (de) * 2002-09-05 2003-11-27 Bosch Gmbh Robert Strukturkörper mit einem elektrochemisch erzeugten porösen Bereich
DE102006057037A1 (de) 2006-12-04 2008-06-05 Bayer Cropscience Ag cis-Alkoxyspirocyclische biphenylsubstituierte Tetramsäure-Derivate
ES2689149T3 (es) 2011-01-25 2018-11-08 Bayer Cropscience Ag Procedimiento para la preparación de derivados de 1-H-pirrolidin-2,4-diona
DE102011080405A1 (de) 2011-08-04 2013-02-07 Bayer Pharma AG Substituierte 3-(Biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur Therapie
US8946124B2 (en) 2011-02-17 2015-02-03 Bayer Intellectual Property Gmbh Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols
KR101925162B1 (ko) * 2011-03-11 2018-12-04 바이엘 인텔렉쳐 프로퍼티 게엠베하 시스-알콕시-치환된 스피로시클릭 1-h-피롤리딘-2,4-디온 유도체
DE102011080406A1 (de) 2011-08-04 2013-02-07 Bayer Pharma AG Substituierte 3-(Biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro8[4.5]dec-3-en-2-one
TWI579260B (zh) * 2012-03-28 2017-04-21 拜耳智慧財產有限公司 用於製備順式－烷氧基－取代之螺環狀苯基乙醯基胺基酸酯及順式－烷氧基－取代之螺環狀１ｈ－吡咯啶－２，４－二酮衍生物之方法
BR112016014772A2 (pt) 2013-12-23 2018-05-22 Syngenta Ltd derivados dihidro-hidantoína com atividade herbicida
CN107857722A (zh) * 2017-11-21 2018-03-30 河南紫微星化学有限公司 一种螺虫乙酯的新型制备方法
CN110128288B (zh) * 2018-02-02 2023-07-28 浙江九洲药业股份有限公司 一种氨基取代的环戊烷甲酸烷基酯衍生物的制备方法
CN111574389B (zh) * 2020-05-14 2023-08-18 河北威远生物化工有限公司 1-氨基-4-取代环己基羧酸及其盐的顺式异构体的制备方法
CN120957968A (zh) 2023-04-07 2025-11-14 安道麦马克西姆有限公司 由环状氨基酸合成环酮
WO2025150038A1 (en) * 2024-01-09 2025-07-17 Adama Makhteshim Ltd. A method for separation of cis and trans isomers of hydantoin-containing spiro-compound from an isomeric mixture

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5523822B2 (enExample) 1971-12-14 1980-06-25
AU666040B2 (en) 1992-10-28 1996-01-25 Bayer Aktiengesellschaft Substituted 1-H-3-aryl-pyrrolidine-2,4-dione derivatives
DE4425617A1 (de) 1994-01-28 1995-08-03 Bayer Ag 1-H-3-Aryl-pyrrolidin-2,4-dion-Derivate
DE4431730A1 (de) 1994-02-09 1995-08-10 Bayer Ag Substituierte 1H-3-Aryl-pyrrolidin-2,4-dion-Derivate
ES2190786T3 (es) 1994-04-05 2003-08-16 Bayer Cropscience Ag 1-h-3-aril-pirrolidin-2,4-dionas alcoxi-alquil-substituidas como herbicidas y pesticidas.
ES2224156T3 (es) 1995-02-13 2005-03-01 Bayer Cropscience Ag 1,2-cetoenoles heterociclicos 2-fenil- substituidos como herbicidas y pesticidas.
ES2184858T3 (es) 1995-05-09 2003-04-16 Bayer Cropscience Ag Cetoenoles alquil-dihalogenofenil substituidos como pesticidas y herbicidas.
TR199701708T1 (xx) 1995-06-28 1998-04-21 Bayer Aktingesellschaft 2,4,5-Triikameli fenilketoenoller.
WO1997002243A1 (de) 1995-06-30 1997-01-23 Bayer Aktiengesellschaft Dialkyl-halogenphenylsubstituierte ketoenole zur verwendung als herbizide und pestizide
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
AU725852B2 (en) 1996-04-02 2000-10-19 Bayer Aktiengesellschaft Substituted phenylketoenols as pesticides and herbicides
DK0915846T3 (da) * 1996-08-05 2003-08-11 Bayer Cropscience Ag 2- og 2,5-substituerede phenylketoenoler
AUPO727097A0 (en) * 1997-06-10 1997-07-03 Unisearch Limited Method of treatment of hepatoma and pharmaceutical compositions for use therein
DE10032587A1 (de) * 2000-07-05 2002-01-17 Bayer Ag 4-Alkoxy-cyclohexan-1-amino-carbonsäureester und Verfahren zu ihrer Herstellung
US6380426B1 (en) * 2001-09-26 2002-04-30 Council Of Scientific And Industrial Research Process for the preparation of a carboxylic acid

Also Published As

Publication number Publication date
JP5899092B2 (ja) 2016-04-06
BR0112245A (pt) 2003-06-24
JP5899091B2 (ja) 2016-04-06
JP2012255028A (ja) 2012-12-27
ZA200300005B (en) 2004-01-02
JP5805561B2 (ja) 2015-11-04
JP2014167018A (ja) 2014-09-11
CN1286820C (zh) 2006-11-29
IL153561A (en) 2008-08-07
EP1309562B1 (de) 2008-05-07
DK1309562T3 (da) 2008-08-11
CN1183118C (zh) 2005-01-05
JP2004502678A (ja) 2004-01-29
JP2012255027A (ja) 2012-12-27
US20040039223A1 (en) 2004-02-26
IL190905A0 (en) 2008-11-03
US20090156402A1 (en) 2009-06-18
AU2001272504A1 (en) 2002-01-14
CN1436176A (zh) 2003-08-13
KR20030058944A (ko) 2003-07-07
MXPA02012889A (es) 2004-07-30
WO2002002532A1 (de) 2002-01-10
IL153561A0 (en) 2003-07-06
CN1616436A (zh) 2005-05-18
US7148377B2 (en) 2006-12-12
KR100758620B1 (ko) 2007-09-13
IL190905A (en) 2010-05-31
EP1309562A1 (de) 2003-05-14
US7511153B2 (en) 2009-03-31
US20070043219A1 (en) 2007-02-22
BR0112245B1 (pt) 2013-09-10
DE50113943D1 (de) 2008-06-19
DE10032587A1 (de) 2002-01-17
JP2012107076A (ja) 2012-06-07
ES2305090T3 (es) 2008-11-01
US7803967B2 (en) 2010-09-28
HK1057897A1 (en) 2004-04-23
ATE394379T1 (de) 2008-05-15

Similar Documents

Publication Publication Date Title
JP5805561B2 (ja) ４−アルコキシ−シクロヘキサン−１−アミノ−カルボン酸
US7799930B2 (en) 1-alkyl-3-aminoindazoles
US20090043111A1 (en) Novel process for ropinirole preparation
Zhou et al. Samarium (II) iodide induced reductive coupling of nitriles with nitro compounds
HU202826B (en) Process for producing (2,6-dichloro-phenyl)-amino-phenyl-acetic acid derivatives
HUP0003905A2 (en) Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
KR101755291B1 (ko) 갑상선 호르몬 및 그것의 염의 제조 방법
JP5618306B2 (ja) 置換４−アミノ−ピリミジンの新規合成
HUT70168A (en) New process for producing imidazopyridine derivatives
US20060035913A1 (en) Method for the production of 2-amino-4-chloro-6-alkoxypyrimidines
HU218680B (hu) Eljárás 1,3-diaza-spiro[4,4]non-1-én-4-on-származékok előállítására és 1-ciano-1-(acil-amino)-ciklopentán intermedierek
US6433170B1 (en) Method for producing 4-[2',5'-diamino-6'-halopyrimidine-4'-yl)amino]- cyclopent-2-enylmethanols
JP3855686B2 (ja) ３，３−ジアルコキシ−２−ヒドロキシイミノ誘導体及びその製造法
EP2938595B1 (fr) Procede de synthese d'une hydrazine utile dans le traitement du virus du papillome
CN118026867A (zh) 一种制备2-(1r,5s,6s)-6-(氨甲基)-3-乙基双环[3.2.0]庚烷-3-烯-6-乙酸的方法
JP2000327629A (ja) フェニル酢酸誘導体、ベンゾニトリル誘導体、およびその製造方法
JP2001288167A (ja) ピロール−２−カルボン酸誘導体の製造法
JPH08245595A (ja) ピラゾールの製造方法

Legal Events

Date Code Title Description
RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20080412

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080620

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080620

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110315

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110615

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111115

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120215

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120222

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120314

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120515

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120914

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20120926

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20121023

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20121030

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

Ref document number: 5127106

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20151109

Year of fee payment: 3

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term