JP5031745B2 - 代謝型グルタミン酸受容体増強性イソインドロン - Google Patents

代謝型グルタミン酸受容体増強性イソインドロン Download PDF

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JP5031745B2
JP5031745B2 JP2008525976A JP2008525976A JP5031745B2 JP 5031745 B2 JP5031745 B2 JP 5031745B2 JP 2008525976 A JP2008525976 A JP 2008525976A JP 2008525976 A JP2008525976 A JP 2008525976A JP 5031745 B2 JP5031745 B2 JP 5031745B2
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alkyl
group
cycloalkyl
benzyl
aryl
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JP2009509920A (ja
JP2009509920A5 (enrdf_load_stackoverflow
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ヴァン・ワゲネン，ブラッドフォード
ウッキラマパンディアン，ラドハクリシュナン
クレイトン，ジョシュア
エグル，イアン
エンプフィールド，ジェームズ・アール
アイザック，メスヴィン
マー，フーペン
スラッシ，アブデルマリック
スティールマン，ゲイリー
アーバネック，レベッカ
ウォルシュ，サリー
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AstraZeneca AB
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AstraZeneca AB
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
JP2008525976A 2005-08-12 2006-02-15 代謝型グルタミン酸受容体増強性イソインドロン Expired - Fee Related JP5031745B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2005/028760 WO2006020879A1 (en) 2004-08-13 2005-08-12 Isoindolone compounds and their use as metabotropic glutamate receptor potentiators
USPCT/US2005/028760 2005-08-12
PCT/US2006/005246 WO2007021308A1 (en) 2005-08-12 2006-02-15 Metabotropic glutamate-receptor-potentiating isoindolones

Publications (3)

Publication Number Publication Date
JP2009509920A JP2009509920A (ja) 2009-03-12
JP2009509920A5 JP2009509920A5 (enrdf_load_stackoverflow) 2009-04-23
JP5031745B2 true JP5031745B2 (ja) 2012-09-26

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JP2008525976A Expired - Fee Related JP5031745B2 (ja) 2005-08-12 2006-02-15 代謝型グルタミン酸受容体増強性イソインドロン
JP2008525977A Pending JP2009509921A (ja) 2005-08-12 2006-02-15 置換イソインドロン類及び代謝調節型グルタミン酸受容体増強剤としてのその使用

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JP2008525977A Pending JP2009509921A (ja) 2005-08-12 2006-02-15 置換イソインドロン類及び代謝調節型グルタミン酸受容体増強剤としてのその使用

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EP (2) EP1912940A1 (enrdf_load_stackoverflow)
JP (2) JP5031745B2 (enrdf_load_stackoverflow)
CN (2) CN101277934A (enrdf_load_stackoverflow)
WO (2) WO2007021308A1 (enrdf_load_stackoverflow)

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WO2007021309A1 (en) 2007-02-22
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