JP5013375B2 - メッセンジャーrna干渉酵素が促進する生細胞における単一タンパク質産生 - Google Patents
メッセンジャーrna干渉酵素が促進する生細胞における単一タンパク質産生 Download PDFInfo
- Publication number
- JP5013375B2 JP5013375B2 JP2007540092A JP2007540092A JP5013375B2 JP 5013375 B2 JP5013375 B2 JP 5013375B2 JP 2007540092 A JP2007540092 A JP 2007540092A JP 2007540092 A JP2007540092 A JP 2007540092A JP 5013375 B2 JP5013375 B2 JP 5013375B2
- Authority
- JP
- Japan
- Prior art keywords
- acid sequence
- nucleic acid
- mrna
- target protein
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62497604P | 2004-11-04 | 2004-11-04 | |
US60/624,976 | 2004-11-04 | ||
PCT/US2005/040107 WO2006055292A2 (en) | 2004-11-04 | 2005-11-04 | Single protein production in living cells facilitated by a messenger rna interferase |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008518623A JP2008518623A (ja) | 2008-06-05 |
JP5013375B2 true JP5013375B2 (ja) | 2012-08-29 |
Family
ID=36407606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007540092A Expired - Fee Related JP5013375B2 (ja) | 2004-11-04 | 2005-11-04 | メッセンジャーrna干渉酵素が促進する生細胞における単一タンパク質産生 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1812582A4 (zh) |
JP (1) | JP5013375B2 (zh) |
KR (1) | KR101064783B1 (zh) |
CN (1) | CN101052713B (zh) |
CA (1) | CA2577180A1 (zh) |
WO (1) | WO2006055292A2 (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007020873A1 (ja) * | 2005-08-16 | 2007-02-22 | Takara Bio Inc. | 免疫不全ウイルス感染症の治療または予防のための核酸 |
WO2010040134A2 (en) | 2008-10-04 | 2010-04-08 | University Of Medicine And Dentistry Of New Jersey | Independently inducible system of gene expression |
EP2848695A1 (en) * | 2013-09-16 | 2015-03-18 | Inria Institut National de Recherche en Informatique et en Automatique | Method for producing metabolites, peptides and recombinant proteins |
CN103484471B (zh) * | 2013-09-30 | 2015-07-08 | 王悦 | 人表皮细胞生长因子核酸序列及大肠杆菌表达载体 |
KR101776368B1 (ko) * | 2014-10-02 | 2017-09-07 | 서울시립대학교 산학협력단 | 전령 rna 나노입자 및 그 제조방법 |
TW202000240A (zh) * | 2018-02-23 | 2020-01-01 | 日商盧卡科學股份有限公司 | 用於在粒線體內使蛋白質表現之核酸、封入前述核酸之脂質膜結構體及其等之用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5807718A (en) * | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
CN103937827A (zh) * | 2003-06-13 | 2014-07-23 | 新泽西内科与牙科大学 | Rna干扰酶及其使用方法 |
-
2005
- 2005-11-04 CN CN2005800323789A patent/CN101052713B/zh not_active Expired - Fee Related
- 2005-11-04 EP EP05851377A patent/EP1812582A4/en not_active Withdrawn
- 2005-11-04 KR KR1020077012576A patent/KR101064783B1/ko not_active IP Right Cessation
- 2005-11-04 WO PCT/US2005/040107 patent/WO2006055292A2/en active Application Filing
- 2005-11-04 JP JP2007540092A patent/JP5013375B2/ja not_active Expired - Fee Related
- 2005-11-04 CA CA002577180A patent/CA2577180A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR101064783B1 (ko) | 2011-09-14 |
JP2008518623A (ja) | 2008-06-05 |
CA2577180A1 (en) | 2006-05-26 |
WO2006055292A3 (en) | 2006-08-03 |
KR20080088350A (ko) | 2008-10-02 |
EP1812582A4 (en) | 2013-03-20 |
WO2006055292A2 (en) | 2006-05-26 |
CN101052713A (zh) | 2007-10-10 |
CN101052713B (zh) | 2011-01-26 |
EP1812582A2 (en) | 2007-08-01 |
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