JP4989004B2 - 加ピロリン酸分解活性化重合（ｐａｐ）：アリル−特異的増幅および核酸配列決定への適応 - Google Patents

加ピロリン酸分解活性化重合（ｐａｐ）：アリル−特異的増幅および核酸配列決定への適応 Download PDF

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JP4989004B2
JP4989004B2 JP2001561783A JP2001561783A JP4989004B2 JP 4989004 B2 JP4989004 B2 JP 4989004B2 JP 2001561783 A JP2001561783 A JP 2001561783A JP 2001561783 A JP2001561783 A JP 2001561783A JP 4989004 B2 JP4989004 B2 JP 4989004B2
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oligonucleotide
nucleic acid
extendable
strand
pyrophosphorolysis
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JP2003526344A (ja
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リュウ，チャン
サマー，スティーヴ・エス
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City of Hope
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2001561783A 2000-02-23 2001-02-22 加ピロリン酸分解活性化重合（ｐａｐ）：アリル−特異的増幅および核酸配列決定への適応 Expired - Fee Related JP4989004B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US18431500P 2000-02-23 2000-02-23
US60/184,315 2000-02-23
US18703500P 2000-03-06 2000-03-06
US60/187,035 2000-03-06
US23718000P 2000-10-03 2000-10-03
US60/237,180 2000-10-03
PCT/US2001/005527 WO2001062975A2 (en) 2000-02-23 2001-02-22 Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination

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JP2003526344A5 JP2003526344A5 (https=) 2008-04-17
JP4989004B2 true JP4989004B2 (ja) 2012-08-01

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US (2) US6534269B2 (https=)
EP (2) EP1259646B1 (https=)
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AT (1) ATE441726T1 (https=)
AU (2) AU2001241621B2 (https=)
CA (1) CA2395391C (https=)
DE (1) DE60139762D1 (https=)
ES (1) ES2330408T3 (https=)
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CN110603326B (zh) * 2017-09-26 2024-03-08 宁波尚宁生物技术有限公司 扩增靶核酸的方法
US11751415B2 (en) 2018-02-02 2023-09-05 Oti Lumionics Inc. Materials for forming a nucleation-inhibiting coating and devices incorporating same
EP3768832B1 (en) * 2018-03-21 2023-11-29 F. Hoffmann-La Roche AG Dna polymerases for efficient and effective incorporation of methylated-dntps
JP7320851B2 (ja) 2018-05-07 2023-08-04 オーティーアイ ルミオニクス インコーポレーテッド 補助電極を提供するための方法および補助電極を含むデバイス
US11268140B2 (en) * 2018-06-12 2022-03-08 Shaofeng Ding Delayed pyrophosphorolysis activated polymerization
JP2022508040A (ja) 2018-11-23 2022-01-19 オーティーアイ ルミオニクス インコーポレーテッド 光透過領域を含むオプトエレクトロニクスデバイス
JP7390739B2 (ja) 2019-03-07 2023-12-04 オーティーアイ ルミオニクス インコーポレーテッド 核生成抑制コーティングを形成するための材料およびそれを組み込んだデバイス
KR102831863B1 (ko) 2019-04-18 2025-07-10 오티아이 루미오닉스 인크. 핵 생성 억제 코팅 형성용 물질 및 이를 포함하는 디바이스
JP7576337B2 (ja) 2019-05-08 2024-11-01 オーティーアイ ルミオニクス インコーポレーテッド 核生成抑制コーティングを形成するための材料およびそれを組み込んだデバイス
US11832473B2 (en) 2019-06-26 2023-11-28 Oti Lumionics Inc. Optoelectronic device including light transmissive regions, with light diffraction characteristics
CN114097102B (zh) 2019-06-26 2023-11-03 Oti照明公司 包括具有光衍射特征的光透射区域的光电设备
CN114342068A (zh) 2019-08-09 2022-04-12 Oti照明公司 包含辅助电极和分区的光电子装置
KR20260036028A (ko) 2019-12-24 2026-03-13 오티아이 루미오닉스 인크. 캡핑 층을 포함하는 발광 장치 및 그 제조방법
CN111108860B (zh) * 2020-01-19 2024-05-14 黑龙江丰沃非凡农业科技发展有限公司 一种仿形播种机
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CN117904281B (zh) * 2024-01-29 2024-11-22 上海科亦生物科技有限公司 检测ugt1a1基因多态性的引物组及试剂盒与方法

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WO2001062975A3 (en) 2002-08-29
ATE441726T1 (de) 2009-09-15
EP1259646B1 (en) 2009-09-02
US7105298B2 (en) 2006-09-12
JP2003526344A (ja) 2003-09-09
US20030092051A1 (en) 2003-05-15
ES2330408T3 (es) 2009-12-10
WO2001062975A9 (en) 2002-10-24
DE60139762D1 (de) 2009-10-15
AU2001241621B2 (en) 2005-08-25
AU4162101A (en) 2001-09-03
CA2395391A1 (en) 2001-08-30
WO2001062975A2 (en) 2001-08-30
US6534269B2 (en) 2003-03-18
CA2395391C (en) 2011-08-02
EP1259646A2 (en) 2002-11-27
EP2112233A1 (en) 2009-10-28
US20020127554A1 (en) 2002-09-12
EP2112233B1 (en) 2013-10-23

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