JP4955543B2 - 炎症性皮膚疾患を治療又は予防するための化合物、製剤及び方法 - Google Patents

炎症性皮膚疾患を治療又は予防するための化合物、製剤及び方法 Download PDF

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Publication number
JP4955543B2
JP4955543B2 JP2007515279A JP2007515279A JP4955543B2 JP 4955543 B2 JP4955543 B2 JP 4955543B2 JP 2007515279 A JP2007515279 A JP 2007515279A JP 2007515279 A JP2007515279 A JP 2007515279A JP 4955543 B2 JP4955543 B2 JP 4955543B2
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topical composition
pharmaceutically acceptable
composition
topical
skin
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JP2008500356A5 (cg-RX-API-DMAC7.html
JP2008500356A (ja
Inventor
ジャック エイ デジョヴィン
トーマス エム ロッシ
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サンズローザ ファーマシューティカル ディヴェロップメント インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2007515279A 2004-05-25 2005-05-25 炎症性皮膚疾患を治療又は予防するための化合物、製剤及び方法 Expired - Fee Related JP4955543B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US57414204P 2004-05-25 2004-05-25
US10/853,585 US7439241B2 (en) 2003-05-27 2004-05-25 Compounds, formulations, and methods for treating or preventing rosacea
US10/853,585 2004-05-25
US60/574,142 2004-05-25
PCT/US2005/018288 WO2005115395A2 (en) 2004-05-25 2005-05-25 Compounds, formulations, and methods for treating or preventing inflammatory skin disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011263425A Division JP5547705B2 (ja) 2004-05-25 2011-12-01 紅斑を治療又は予防するための組成物

Publications (3)

Publication Number Publication Date
JP2008500356A JP2008500356A (ja) 2008-01-10
JP2008500356A5 JP2008500356A5 (cg-RX-API-DMAC7.html) 2008-03-27
JP4955543B2 true JP4955543B2 (ja) 2012-06-20

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JP2007515279A Expired - Fee Related JP4955543B2 (ja) 2004-05-25 2005-05-25 炎症性皮膚疾患を治療又は予防するための化合物、製剤及び方法
JP2011263425A Expired - Fee Related JP5547705B2 (ja) 2004-05-25 2011-12-01 紅斑を治療又は予防するための組成物

Family Applications After (1)

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JP2011263425A Expired - Fee Related JP5547705B2 (ja) 2004-05-25 2011-12-01 紅斑を治療又は予防するための組成物

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Country Link
EP (2) EP1761266B1 (cg-RX-API-DMAC7.html)
JP (2) JP4955543B2 (cg-RX-API-DMAC7.html)
KR (1) KR101257046B1 (cg-RX-API-DMAC7.html)
CN (2) CN104490884A (cg-RX-API-DMAC7.html)
AU (1) AU2005247467B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0511519A (cg-RX-API-DMAC7.html)
CA (2) CA2567401C (cg-RX-API-DMAC7.html)
DK (1) DK1761266T3 (cg-RX-API-DMAC7.html)
ES (2) ES2424644T3 (cg-RX-API-DMAC7.html)
MX (1) MXPA06013649A (cg-RX-API-DMAC7.html)
NZ (1) NZ552325A (cg-RX-API-DMAC7.html)
PL (1) PL1761266T3 (cg-RX-API-DMAC7.html)
PT (1) PT1761266E (cg-RX-API-DMAC7.html)
SI (1) SI1761266T1 (cg-RX-API-DMAC7.html)
WO (1) WO2005115395A2 (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
EP1761266A4 (en) 2009-11-11
EP2481412A1 (en) 2012-08-01
AU2005247467B2 (en) 2010-12-02
JP2012072176A (ja) 2012-04-12
CN104490884A (zh) 2015-04-08
CA2567401A1 (en) 2005-12-08
EP1761266A2 (en) 2007-03-14
CA2824612C (en) 2016-08-16
CA2567401C (en) 2013-11-12
PL1761266T3 (pl) 2013-09-30
WO2005115395A2 (en) 2005-12-08
NZ552325A (en) 2010-11-26
JP5547705B2 (ja) 2014-07-16
KR101257046B1 (ko) 2013-04-22
CA2824612A1 (en) 2005-12-08
EP2481412B1 (en) 2017-09-27
EP1761266B1 (en) 2013-05-08
WO2005115395A3 (en) 2009-04-09
KR20070032716A (ko) 2007-03-22
ES2647618T3 (es) 2017-12-22
SI1761266T1 (sl) 2013-08-30
JP2008500356A (ja) 2008-01-10
ES2424644T3 (es) 2013-10-07
BRPI0511519A (pt) 2007-12-26
CN101426502A (zh) 2009-05-06
AU2005247467A1 (en) 2005-12-08
PT1761266E (pt) 2013-06-04
MXPA06013649A (es) 2007-07-09
DK1761266T3 (da) 2013-08-05

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