JP4932735B2 - アミノピリミジン化合物および使用方法 - Google Patents

アミノピリミジン化合物および使用方法 Download PDF

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Publication number
JP4932735B2
JP4932735B2 JP2007546989A JP2007546989A JP4932735B2 JP 4932735 B2 JP4932735 B2 JP 4932735B2 JP 2007546989 A JP2007546989 A JP 2007546989A JP 2007546989 A JP2007546989 A JP 2007546989A JP 4932735 B2 JP4932735 B2 JP 4932735B2
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Japan
Prior art keywords
ethyl
pyrimidin
ylamino
dione
dimethyl
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Expired - Lifetime
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JP2007546989A
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Japanese (ja)
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JP2008524248A5 (https=
JP2008524248A (ja
Inventor
スミス，エイドリアン・レオナード
ブレナン，ポール・エドワード
デモリン，フレネル・フイルス
リウ，カン
パラス，ニツク・エイ
レツツ，ダニエル・マーテイン
レインボー，エリザベス
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アムジエン・インコーポレーテツド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2007546989A 2004-12-17 2005-12-16 アミノピリミジン化合物および使用方法 Expired - Lifetime JP4932735B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63660404P 2004-12-17 2004-12-17
US60/636,604 2004-12-17
PCT/US2005/045863 WO2006066172A1 (en) 2004-12-17 2005-12-16 Aminopyrimidine compounds and methods of use

Publications (3)

Publication Number Publication Date
JP2008524248A JP2008524248A (ja) 2008-07-10
JP2008524248A5 JP2008524248A5 (https=) 2008-11-13
JP4932735B2 true JP4932735B2 (ja) 2012-05-16

Family

ID=36588221

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007546989A Expired - Lifetime JP4932735B2 (ja) 2004-12-17 2005-12-16 アミノピリミジン化合物および使用方法

Country Status (9)

Country Link
US (2) US7786132B2 (https=)
EP (1) EP1831207B1 (https=)
JP (1) JP4932735B2 (https=)
CN (1) CN101115749B (https=)
AU (1) AU2005316312B2 (https=)
CA (1) CA2590939C (https=)
ES (1) ES2397362T3 (https=)
MX (1) MX2007007032A (https=)
WO (1) WO2006066172A1 (https=)

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US8063035B2 (en) 2007-05-16 2011-11-22 Eli Lilly And Company Triazolyl aminopyrimidine compounds
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US9566280B2 (en) 2014-01-28 2017-02-14 Massachusetts Institute Of Technology Combination therapies and methods of use thereof for treating cancer
CN104860900A (zh) * 2014-02-25 2015-08-26 中国药科大学 噻唑类化合物、其制备方法及其在制药中的用途
CN105884711A (zh) * 2014-12-16 2016-08-24 中国药科大学 噻唑类化合物、其制备方法及其在制药中的用途
PT3319939T (pt) * 2015-07-08 2025-03-05 Cv6 Therapeutics Ni Ltd Inibidores de desoxiuridina-trifosfatase contendo hidantoína
AU2016296905B2 (en) 2015-07-23 2018-07-05 Centre National De La Recherche Scientifique Use of a combination of Dbait molecule and parp inhibitors to treat cancer
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PT3494119T (pt) 2016-07-29 2024-12-10 Pgi Drug Discovery Llc Compostos e composições e seus usos
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WO2018162439A1 (en) 2017-03-08 2018-09-13 Onxeo New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule
CA3070993C (en) 2017-08-02 2025-05-20 Sunovion Pharmaceuticals Inc. ISOCHROMANE COMPOUNDS AND THEIR USES
WO2019025250A1 (en) 2017-08-04 2019-02-07 Basf Se SUBSTITUTED TRIFLUOROMETHYLOXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI
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CN112125879A (zh) * 2020-09-29 2020-12-25 浙江永太科技股份有限公司 一种卡格列净中间体2-(4-氟苯基)噻吩的制备方法
CN114133337A (zh) * 2020-12-14 2022-03-04 成都泰蓉生物科技有限公司 一种2-取代的赖氨酸的制备方法
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Also Published As

Publication number Publication date
CN101115749B (zh) 2011-06-22
WO2006066172A1 (en) 2006-06-22
JP2008524248A (ja) 2008-07-10
EP1831207A1 (en) 2007-09-12
ES2397362T3 (es) 2013-03-06
EP1831207A4 (en) 2010-09-15
CA2590939A1 (en) 2006-06-22
AU2005316312B2 (en) 2009-10-22
AU2005316312A1 (en) 2006-06-22
US7786132B2 (en) 2010-08-31
MX2007007032A (es) 2007-07-04
EP1831207B1 (en) 2012-11-14
US20100010014A1 (en) 2010-01-14
CA2590939C (en) 2011-10-18
US20070185133A1 (en) 2007-08-09
US7858785B2 (en) 2010-12-28
CN101115749A (zh) 2008-01-30

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