JP4889219B2 - 腹部不快感の処置のためのプロスタグランジン誘導体 - Google Patents

腹部不快感の処置のためのプロスタグランジン誘導体 Download PDF

Info

Publication number
JP4889219B2
JP4889219B2 JP2004564537A JP2004564537A JP4889219B2 JP 4889219 B2 JP4889219 B2 JP 4889219B2 JP 2004564537 A JP2004564537 A JP 2004564537A JP 2004564537 A JP2004564537 A JP 2004564537A JP 4889219 B2 JP4889219 B2 JP 4889219B2
Authority
JP
Japan
Prior art keywords
formula
composition according
hydroxy
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2004564537A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006513232A (ja
JP2006513232A5 (enExample
Inventor
隆司 上野
祐子 久能
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32717850&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4889219(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Publication of JP2006513232A publication Critical patent/JP2006513232A/ja
Publication of JP2006513232A5 publication Critical patent/JP2006513232A5/ja
Application granted granted Critical
Publication of JP4889219B2 publication Critical patent/JP4889219B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/56—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2004564537A 2002-12-27 2003-12-26 腹部不快感の処置のためのプロスタグランジン誘導体 Expired - Lifetime JP4889219B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US43646202P 2002-12-27 2002-12-27
US43646302P 2002-12-27 2002-12-27
US60/436,463 2002-12-27
US60/436,462 2002-12-27
PCT/JP2003/016857 WO2004060377A1 (en) 2002-12-27 2003-12-26 Derivatives of prostaglandins for treating abdominal discomfort

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011240314A Division JP2012031202A (ja) 2002-12-27 2011-11-01 腹部不快感の処置のためのプロスタグランジン誘導体

Publications (3)

Publication Number Publication Date
JP2006513232A JP2006513232A (ja) 2006-04-20
JP2006513232A5 JP2006513232A5 (enExample) 2007-02-15
JP4889219B2 true JP4889219B2 (ja) 2012-03-07

Family

ID=32717850

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004564537A Expired - Lifetime JP4889219B2 (ja) 2002-12-27 2003-12-26 腹部不快感の処置のためのプロスタグランジン誘導体
JP2011240314A Pending JP2012031202A (ja) 2002-12-27 2011-11-01 腹部不快感の処置のためのプロスタグランジン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011240314A Pending JP2012031202A (ja) 2002-12-27 2011-11-01 腹部不快感の処置のためのプロスタグランジン誘導体

Country Status (15)

Country Link
US (3) US7795312B2 (enExample)
EP (2) EP1575596B1 (enExample)
JP (2) JP4889219B2 (enExample)
KR (2) KR101164838B1 (enExample)
CN (1) CN1753680B (enExample)
AR (1) AR042670A1 (enExample)
AU (1) AU2003292556B2 (enExample)
BR (1) BRPI0317740B8 (enExample)
CA (1) CA2510051C (enExample)
ES (1) ES2591252T3 (enExample)
MX (1) MXPA05006981A (enExample)
NO (1) NO335441B1 (enExample)
NZ (1) NZ541110A (enExample)
TW (1) TWI336254B (enExample)
WO (1) WO2004060377A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
PT1562604E (pt) * 2002-10-23 2012-04-09 Sucampo Ag Compostos de prostaglandina para o tratamento de obesidade
WO2005002588A1 (en) * 2003-07-03 2005-01-13 Sucampo Ag Enteric coated composition comprising prostaglandin analogs as chloride channel opener
TWI387454B (zh) * 2004-09-02 2013-03-01 蘇坎波公司 治療胃腸道疾病之方法及組成物
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
CN101180096B (zh) * 2005-03-21 2015-04-22 苏坎波公司 用于治疗粘膜疾病的方法和组合物
BRPI0610557A2 (pt) * 2005-04-12 2010-06-29 Sucampo Ag uso combinado de composto prostaglandina e inibidor da bomba de próton para o tratamento de distúrbios gastrointestinais e composição farmacêutica
US7868045B2 (en) 2006-09-06 2011-01-11 Sucampo Ag Method for promoting gastrointestinal bicarbonate secretion
WO2008108322A2 (en) * 2007-02-27 2008-09-12 Sucampo Ag Composition and method for protecting mitochondria
US20090012165A1 (en) * 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
TW201118084A (en) * 2009-09-18 2011-06-01 Adolor Corp The use of an opioid receptor antagonist for the treatment or prevention of gastrointestinal tract disorders
IT1402047B1 (it) * 2010-10-19 2013-08-28 Cross Pharma Sa Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali
JO3438B1 (ar) 2011-04-13 2019-10-20 Epizyme Inc مركبات بنزين مستبدلة بأريل أو أريل غير متجانس
CN104379140A (zh) * 2012-04-23 2015-02-25 苏坎波公司 用于治疗具有腹泻的肠易激综合征的方法
US10092572B2 (en) 2012-10-15 2018-10-09 Epizyme, Inc. Substituted benzene compounds
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02109A (ja) * 1987-10-02 1990-01-05 Ueno Seiyaku Oyo Kenkyusho:Kk 下剤
WO2002020007A1 (en) * 2000-09-05 2002-03-14 Sucampo Ag Cathartic composition
US6492417B1 (en) * 1997-12-22 2002-12-10 Alcon Manufacturing, Ltd. 11-deoxy-16-fluoro-PGF2α analogs as FP receptor antagonists
JP2005504836A (ja) * 2001-08-31 2005-02-17 スキャンポ・アーゲー クロライドチャンネルオープナーとしてのプロスタグランジンアナログ
JP2005513014A (ja) * 2001-11-14 2005-05-12 スキャンポ・アーゲー 便秘の処置用のプロスタグランジンアナログを含む用量単位
JP4332353B2 (ja) * 2001-05-02 2009-09-16 スキャンポ・アーゲー １５−ケト−プロスタグランジン類を含む薬物誘発性便秘処置用組成物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1581886A (en) * 1977-05-26 1980-12-31 May & Baker Ltd Prostanol derivatives
CA1322749C (en) 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5166174A (en) 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
US5221763A (en) 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5317032A (en) 1987-10-02 1994-05-31 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Prostaglandin cathartic
JP2579193B2 (ja) 1988-07-19 1997-02-05 小野薬品工業株式会社 １６，１６−ジフルオロ−１５−オキソ−１５−デオキシｐｇｅ誘導体
TW249226B (enExample) 1990-04-04 1995-06-11 Aderk Ueno Kk
DE69130586T2 (de) 1990-05-01 1999-06-17 R-Tech Ueno, Ltd., Osaka Behandlung von Pankreaskrankheit mit 15-keto-Prostaglandin E-Derivaten
CA2150287C (en) 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
CN102126998B (zh) 1996-06-10 2013-06-12 苏坎波公司 内皮素拮抗剂
US6046239A (en) * 1997-08-05 2000-04-04 American Home Products Corporation Anthranilic acid analogs
NZ336960A (en) * 1997-11-28 2001-02-23 R Tech Ueno Ltd Use of 15-keto-prostaglandin E compounds for the preparation of medicaments for use as endothelin antagonists
CZ303625B6 (cs) 1999-10-15 2013-01-16 Sucampo Ag Stabilní farmaceutický prostredek obsahující bicyklickou slouceninu a acyglycerol, bicyklická sloucenina, zpusob stabilizace bicyklické slouceniny, farmaceutický prostredek obsahující bicyklickou slouceninu
CA2404767C (en) * 2000-04-06 2010-12-07 Sucampo Ag Bile secretion promoting composition containing a 15-keto prostaglandin
ES2301681T3 (es) * 2001-05-18 2008-07-01 Sucampo Ag Composicion inductora catartica.
TWI263505B (en) * 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02109A (ja) * 1987-10-02 1990-01-05 Ueno Seiyaku Oyo Kenkyusho:Kk 下剤
US6492417B1 (en) * 1997-12-22 2002-12-10 Alcon Manufacturing, Ltd. 11-deoxy-16-fluoro-PGF2α analogs as FP receptor antagonists
WO2002020007A1 (en) * 2000-09-05 2002-03-14 Sucampo Ag Cathartic composition
JP4332353B2 (ja) * 2001-05-02 2009-09-16 スキャンポ・アーゲー １５−ケト−プロスタグランジン類を含む薬物誘発性便秘処置用組成物
JP2005504836A (ja) * 2001-08-31 2005-02-17 スキャンポ・アーゲー クロライドチャンネルオープナーとしてのプロスタグランジンアナログ
JP2005513014A (ja) * 2001-11-14 2005-05-12 スキャンポ・アーゲー 便秘の処置用のプロスタグランジンアナログを含む用量単位

Also Published As

Publication number Publication date
ES2591252T3 (es) 2016-11-25
EP1575596A1 (en) 2005-09-21
KR101164838B1 (ko) 2012-07-11
AR042670A1 (es) 2005-06-29
TW200418491A (en) 2004-10-01
BRPI0317740B1 (pt) 2018-09-18
AU2003292556A1 (en) 2004-07-29
BR0317740A (pt) 2005-11-22
CN1753680A (zh) 2006-03-29
KR20120045051A (ko) 2012-05-08
US20100298424A1 (en) 2010-11-25
NO20053623D0 (no) 2005-07-26
CN1753680B (zh) 2010-12-08
JP2006513232A (ja) 2006-04-20
NZ541110A (en) 2008-11-28
AU2003292556B2 (en) 2009-09-10
US20130217770A1 (en) 2013-08-22
US20040138308A1 (en) 2004-07-15
TWI336254B (en) 2011-01-21
WO2004060377A1 (en) 2004-07-22
CA2510051A1 (en) 2004-07-22
NO20053623L (no) 2005-09-26
EP2281564A2 (en) 2011-02-09
US7795312B2 (en) 2010-09-14
BRPI0317740B8 (pt) 2021-05-25
EP1575596B1 (en) 2016-06-22
CA2510051C (en) 2016-07-05
EP2281564A3 (en) 2012-09-05
MXPA05006981A (es) 2005-12-14
JP2012031202A (ja) 2012-02-16
KR20050086950A (ko) 2005-08-30
NO335441B1 (no) 2014-12-15

Similar Documents

Publication Publication Date Title
JP2012031202A (ja) 腹部不快感の処置のためのプロスタグランジン誘導体
JP5213448B2 (ja) 末梢血管疾患の処置のための方法および組成物
JP4332353B2 (ja) １５−ケト−プロスタグランジン類を含む薬物誘発性便秘処置用組成物
JP2010532314A (ja) Ｎｓａｉｄおよびプロスタグランジン化合物の医薬的組み合わせ
JP2008291033A (ja) １５−ケトプロスタグランジンを含む胆汁分泌促進剤組成物
AU2002251554A1 (en) Composition for Treating Drug-Induced Constipation
JP5294559B2 (ja) クロライドチャンネルオープナーとしてプロスタグランジンアナログを含む腸溶性組成物
JP5427029B2 (ja) 消化管の重炭酸分泌を促進するための方法および組成物
JP4705782B2 (ja) 肥満の処置のためのプロスタグランジン化合物
JP2003527430A (ja) １５−ケトプロスタグランジンまたはその誘導体を含むアポトーシス抑制剤
JP4091132B2 (ja) 門脈圧亢進抑制剤
JP2014515004A (ja) イオン輸送体の調節方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20061220

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20061220

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100126

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100422

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100430

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100726

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101221

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110318

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110328

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110421

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110802

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20111101

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20111206

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20111213

R150 Certificate of patent or registration of utility model

Ref document number: 4889219

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20141222

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20141222

Year of fee payment: 3

R153 Grant of patent term extension

Free format text: JAPANESE INTERMEDIATE CODE: R153

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20141222

Year of fee payment: 3

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R153 Grant of patent term extension

Free format text: JAPANESE INTERMEDIATE CODE: R153

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

S201 Request for registration of exclusive licence

Free format text: JAPANESE INTERMEDIATE CODE: R314201

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R314531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R314533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350