JP4861468B2 - 磁性粒子を含む液体から該粒子を分離するための装置、およびかかる装置での使用に適した容器のアレイ - Google Patents
磁性粒子を含む液体から該粒子を分離するための装置、およびかかる装置での使用に適した容器のアレイ Download PDFInfo
- Publication number
- JP4861468B2 JP4861468B2 JP2009501913A JP2009501913A JP4861468B2 JP 4861468 B2 JP4861468 B2 JP 4861468B2 JP 2009501913 A JP2009501913 A JP 2009501913A JP 2009501913 A JP2009501913 A JP 2009501913A JP 4861468 B2 JP4861468 B2 JP 4861468B2
- Authority
- JP
- Japan
- Prior art keywords
- container
- array
- magnet
- containers
- pipette tip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000007788 liquid Substances 0.000 title claims description 34
- 239000006249 magnetic particle Substances 0.000 title claims description 23
- 239000002245 particle Substances 0.000 title claims description 10
- 239000002699 waste material Substances 0.000 claims description 50
- 239000000463 material Substances 0.000 claims description 8
- 238000001746 injection moulding Methods 0.000 claims description 4
- 239000004033 plastic Substances 0.000 claims description 3
- 239000012815 thermoplastic material Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 15
- 239000012530 fluid Substances 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 239000004793 Polystyrene Substances 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
- B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/005—Pretreatment specially adapted for magnetic separation
- B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/10—Magnetic separation acting directly on the substance being separated with cylindrical material carriers
- B03C1/12—Magnetic separation acting directly on the substance being separated with cylindrical material carriers with magnets moving during operation; with movable pole pieces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06075785A EP1839756A1 (en) | 2006-03-31 | 2006-03-31 | Apparatus for separating magnetic particles from liquids containing said particles, and an array of vessels suitable for use with such an apparatus |
| EP06075785.3 | 2006-03-31 | ||
| PCT/EP2007/002491 WO2007112862A2 (en) | 2006-03-31 | 2007-03-21 | Apparatus for separating magnetic particles from liquids containing said particles, and an array of vessels suitable for use with such an apparatus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009531676A JP2009531676A (ja) | 2009-09-03 |
| JP2009531676A5 JP2009531676A5 (enExample) | 2010-03-25 |
| JP4861468B2 true JP4861468B2 (ja) | 2012-01-25 |
Family
ID=36910803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009501913A Expired - Fee Related JP4861468B2 (ja) | 2006-03-31 | 2007-03-21 | 磁性粒子を含む液体から該粒子を分離するための装置、およびかかる装置での使用に適した容器のアレイ |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8470267B2 (enExample) |
| EP (2) | EP1839756A1 (enExample) |
| JP (1) | JP4861468B2 (enExample) |
| CN (1) | CN101415498B (enExample) |
| CA (1) | CA2646670C (enExample) |
| WO (1) | WO2007112862A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
| US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
| US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
| WO2005011867A2 (en) | 2003-07-31 | 2005-02-10 | Handylab, Inc. | Processing particle-containing samples |
| US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
| US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US8883490B2 (en) | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
| US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
| US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| WO2007112114A2 (en) | 2006-03-24 | 2007-10-04 | Handylab, Inc. | Integrated system for processing microfluidic samples, and method of using same |
| EP1839756A1 (en) | 2006-03-31 | 2007-10-03 | F.Hoffmann-La Roche Ag | Apparatus for separating magnetic particles from liquids containing said particles, and an array of vessels suitable for use with such an apparatus |
| WO2008061165A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic cartridge and method of making same |
| US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
| EP3222733B1 (en) | 2007-07-13 | 2021-04-07 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
| US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
| US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
| US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
| USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
| CN113145296B (zh) | 2009-05-15 | 2024-03-29 | 简·探针公司 | 用于在执行磁性分离工序的仪器中实现磁体的自动移动的方法和设备 |
| JP5623888B2 (ja) | 2009-12-10 | 2014-11-12 | エフ.ホフマン−ラ ロシュアーゲーF.Hoffmann−La Roche Aktiengesellschaft | 分析対象物を分離して検出する方法 |
| SE535983C2 (sv) * | 2010-04-20 | 2013-03-19 | Noviscens Ab | Spruta |
| EP3709025A1 (en) | 2011-04-15 | 2020-09-16 | Becton, Dickinson and Company | Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection |
| CN103959070B (zh) | 2011-09-30 | 2017-05-10 | 贝克顿·迪金森公司 | 组合试剂条 |
| USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
| CN104040238B (zh) | 2011-11-04 | 2017-06-27 | 汉迪拉布公司 | 多核苷酸样品制备装置 |
| EP2607904B1 (en) * | 2011-12-21 | 2020-01-15 | Roche Diagnostics GmbH | Method for disposing of a liquid within an automated analytical system, tip rack assembly and analytical system |
| JP2013134069A (ja) * | 2011-12-26 | 2013-07-08 | Hitachi High-Technologies Corp | 自動分析装置 |
| US10822644B2 (en) | 2012-02-03 | 2020-11-03 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
| US20130327695A1 (en) * | 2012-06-08 | 2013-12-12 | Massachusetts Institute Of Technology | Magnet Configurations For Improved Separations Of Magnetic And Non-Magnetic Materials |
| ES2744596T3 (es) | 2013-03-15 | 2020-02-25 | Becton Dickinson Co | Tubo de procesamiento y bandeja portadora |
| US10220392B2 (en) | 2013-03-15 | 2019-03-05 | Becton, Dickinson And Company | Process tube and carrier tray |
| US11865544B2 (en) | 2013-03-15 | 2024-01-09 | Becton, Dickinson And Company | Process tube and carrier tray |
| CN203700334U (zh) * | 2013-11-01 | 2014-07-09 | 艾康生物技术(杭州)有限公司 | 核酸提取仪 |
| US9656267B2 (en) * | 2015-09-17 | 2017-05-23 | Nvigen, Inc. | Magnetic rack |
| JP6771903B2 (ja) * | 2016-02-29 | 2020-10-21 | シスメックス株式会社 | 検体前処理装置、検体前処理カートリッジおよび検体前処理方法 |
| EP3213819B1 (en) * | 2016-03-02 | 2021-09-29 | F. Hoffmann-La Roche AG | Device and method for separation |
| JP2019520825A (ja) * | 2016-06-30 | 2019-07-25 | ジェネラル オートメーション ラボ テクノロジーズ インコーポレイテッド | 磁性粒子を用いたハイスループット微生物学適用高分解能システム、キット、装置および方法 |
| US9753044B1 (en) | 2016-07-13 | 2017-09-05 | William J. Palin | Apparatus and method for detecting paramagnetic and superparamagnetic biomarkers |
| JP6995090B2 (ja) * | 2019-07-11 | 2022-01-14 | 日本電子株式会社 | 自動分析装置および自動分析装置の制御方法 |
| EP3834939A1 (en) * | 2019-12-12 | 2021-06-16 | TTP plc | Sample preparation system |
| US11327087B2 (en) * | 2020-04-13 | 2022-05-10 | Brevitest Technologies, Llc | Automated driving of an assay with spaced magnets |
| CA3237338A1 (en) * | 2021-11-03 | 2023-05-11 | Fluent Biosciences Inc. | Devices for improving sample preparation and processing |
| WO2025196474A1 (en) * | 2024-03-17 | 2025-09-25 | Askari Mehdi | Magnetic filter system in the electromechanical equipment of the refineries |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6484151A (en) * | 1987-09-26 | 1989-03-29 | Olympus Optical Co | Dilution plate for liquid analyzing device |
| WO1997005492A1 (en) * | 1995-07-31 | 1997-02-13 | Precision System Science Co., Ltd | Vessel |
| JPH11156231A (ja) * | 1997-09-29 | 1999-06-15 | F Hoffmann La Roche Ag | 液体中の懸濁磁性粒子の分離装置 |
| JP2001221806A (ja) * | 1999-12-24 | 2001-08-17 | Roche Diagnostics Gmbh | マルチチャンバ構造においてサンプルを処理するためのシステム |
| JP2004361422A (ja) * | 1995-07-31 | 2004-12-24 | Precision System Science Co Ltd | 容器 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10219541C1 (de) | 2002-05-02 | 2003-12-11 | Koenig & Bauer Ag | Vorrichtung zum Erfassen eines Bahnbruckes an einer eine Bahn verarbeitenden Maschine |
| DE9006918U1 (de) * | 1990-06-20 | 1990-08-23 | Walter Sarstedt Geräte und Verbrauchsmaterial für Medizin und Wissenschaft, 5223 Nümbrecht | Pipettenspitzenbehälter |
| DE4301084A1 (de) | 1993-01-16 | 1994-07-21 | Claas Saulgau Gmbh | Kreiselheumaschine |
| ATE212723T1 (de) * | 1993-09-17 | 2002-02-15 | Hoffmann La Roche | Analysengerät mit einer vorrichtung zum abtrennen magnetischer mikropartikel |
| DE4423878A1 (de) | 1994-07-07 | 1996-01-11 | Boehringer Mannheim Gmbh | Vorrichtung und Verfahren zum Abscheiden von magnetischen Mikropartikeln |
| ATE172890T1 (de) * | 1995-02-21 | 1998-11-15 | Iqbal W Dr Siddiqi | Apparat und verfahren zum mischen und trennen durch verwendung von magnetischen teilchen |
| US20030127396A1 (en) * | 1995-02-21 | 2003-07-10 | Siddiqi Iqbal Waheed | Apparatus and method for processing magnetic particles |
| IL123210A0 (en) * | 1998-02-06 | 1998-09-24 | Gombinsky Moshe | A device and system for the collection of magnetic particles |
| US6065617A (en) * | 1998-06-15 | 2000-05-23 | Bayer Corporation | Sample tube rack |
| DE10063984A1 (de) * | 2000-12-19 | 2002-06-20 | Bilatec Ges Zur Entwicklung Bi | Vorrichtungen zur magnetischen Abtrennung von Magnetpartikeln |
| DE10156790A1 (de) * | 2001-11-19 | 2003-06-18 | Chemagen Biopolymer Technologi | Vorrichtung und Verfahren zum Behandeln von Magnetpartikeln |
| WO2003097240A2 (en) * | 2002-05-17 | 2003-11-27 | Gen-Probe Incorporated | Sample carrier having sample tube blocking means and drip shield for use therewith |
| ATE504324T1 (de) * | 2003-02-24 | 2011-04-15 | Becton Dickinson France | Vorrichtung zur gruppierung von spritzen |
| US7000785B2 (en) * | 2003-04-03 | 2006-02-21 | Bio-Rad Laboratories, Inc. | Tube rack accommodating a range of tube diameters |
| US8211386B2 (en) * | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
| EP1839756A1 (en) | 2006-03-31 | 2007-10-03 | F.Hoffmann-La Roche Ag | Apparatus for separating magnetic particles from liquids containing said particles, and an array of vessels suitable for use with such an apparatus |
-
2006
- 2006-03-31 EP EP06075785A patent/EP1839756A1/en not_active Withdrawn
-
2007
- 2007-03-21 JP JP2009501913A patent/JP4861468B2/ja not_active Expired - Fee Related
- 2007-03-21 CN CN2007800122011A patent/CN101415498B/zh not_active Expired - Fee Related
- 2007-03-21 US US12/294,509 patent/US8470267B2/en not_active Expired - Fee Related
- 2007-03-21 EP EP07711987A patent/EP2001597A2/en not_active Withdrawn
- 2007-03-21 CA CA2646670A patent/CA2646670C/en not_active Expired - Fee Related
- 2007-03-21 WO PCT/EP2007/002491 patent/WO2007112862A2/en not_active Ceased
-
2013
- 2013-05-22 US US13/900,389 patent/US9381519B2/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6484151A (en) * | 1987-09-26 | 1989-03-29 | Olympus Optical Co | Dilution plate for liquid analyzing device |
| WO1997005492A1 (en) * | 1995-07-31 | 1997-02-13 | Precision System Science Co., Ltd | Vessel |
| JP2004361422A (ja) * | 1995-07-31 | 2004-12-24 | Precision System Science Co Ltd | 容器 |
| JPH11156231A (ja) * | 1997-09-29 | 1999-06-15 | F Hoffmann La Roche Ag | 液体中の懸濁磁性粒子の分離装置 |
| JP2001221806A (ja) * | 1999-12-24 | 2001-08-17 | Roche Diagnostics Gmbh | マルチチャンバ構造においてサンプルを処理するためのシステム |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2646670A1 (en) | 2007-10-11 |
| CA2646670C (en) | 2011-09-20 |
| JP2009531676A (ja) | 2009-09-03 |
| US20130256205A1 (en) | 2013-10-03 |
| US8470267B2 (en) | 2013-06-25 |
| US9381519B2 (en) | 2016-07-05 |
| US20100284864A1 (en) | 2010-11-11 |
| EP2001597A2 (en) | 2008-12-17 |
| EP1839756A1 (en) | 2007-10-03 |
| WO2007112862A3 (en) | 2007-12-27 |
| WO2007112862A2 (en) | 2007-10-11 |
| CN101415498B (zh) | 2012-11-07 |
| CN101415498A (zh) | 2009-04-22 |
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| GB2204950A (en) | Cytology sample chamber |
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