JP4824562B2 - アミドメチル置換１−（カルボキシアルキル）−シクロペンチルカルボニルアミノ−ベンズアゼピン−ｎ−酢酸誘導体、これらを製造するための方法および中間生成物およびこれら化合物を含有する医薬 - Google Patents
アミドメチル置換１−（カルボキシアルキル）−シクロペンチルカルボニルアミノ−ベンズアゼピン−ｎ−酢酸誘導体、これらを製造するための方法および中間生成物およびこれら化合物を含有する医薬 Download PDFInfo
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- JP4824562B2 JP4824562B2 JP2006527420A JP2006527420A JP4824562B2 JP 4824562 B2 JP4824562 B2 JP 4824562B2 JP 2006527420 A JP2006527420 A JP 2006527420A JP 2006527420 A JP2006527420 A JP 2006527420A JP 4824562 B2 JP4824562 B2 JP 4824562B2
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- C—CHEMISTRY; METALLURGY
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- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
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- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10344848A DE10344848A1 (de) | 2003-09-26 | 2003-09-26 | Amidomethyl-substituierte l-(Carboxyalkyl)-cyclopentylcarbonylamino-benzazepin-N-essigsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enhaltende Arzneimittel |
| DE10344848.9 | 2003-09-26 | ||
| EP04100065 | 2004-01-12 | ||
| EP04100065.4 | 2004-01-12 | ||
| PCT/EP2004/052289 WO2005030795A1 (en) | 2003-09-26 | 2004-09-23 | Amidomethyl substituted 1-(carboxyalkyl)-cyclopentylcarbonylamino-benzazepine-n-acetic acid derivatives, process and intermediate products for their preparation and medicaments containing these compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007535482A JP2007535482A (ja) | 2007-12-06 |
| JP2007535482A5 JP2007535482A5 (ko) | 2011-08-04 |
| JP4824562B2 true JP4824562B2 (ja) | 2011-11-30 |
Family
ID=34395054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006527420A Expired - Fee Related JP4824562B2 (ja) | 2003-09-26 | 2004-09-23 | アミドメチル置換１−（カルボキシアルキル）−シクロペンチルカルボニルアミノ−ベンズアゼピン−ｎ−酢酸誘導体、これらを製造するための方法および中間生成物およびこれら化合物を含有する医薬 |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1670814A1 (ko) |
| JP (1) | JP4824562B2 (ko) |
| KR (1) | KR101264934B1 (ko) |
| AR (1) | AR045798A1 (ko) |
| AU (1) | AU2004276002B2 (ko) |
| BR (1) | BRPI0414744A (ko) |
| CA (1) | CA2539895A1 (ko) |
| HK (1) | HK1096105A1 (ko) |
| IL (1) | IL174373A (ko) |
| MX (1) | MXPA06003226A (ko) |
| NO (1) | NO20061821L (ko) |
| RU (1) | RU2368601C2 (ko) |
| SA (1) | SA04250283B1 (ko) |
| TW (1) | TWI332947B (ko) |
| WO (1) | WO2005030795A1 (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005112939A1 (en) * | 2004-05-14 | 2005-12-01 | Solvay Pharmaceuticals Gmbh | Medicaments containing dually acting inhibitors of neutral endopeptidase and of human soluble endopeptidase for the treatment of sexual dysfunction |
| EP1776095A1 (en) * | 2004-06-23 | 2007-04-25 | Solvay Pharmaceuticals GmbH | Pharmaceutical compositions comprising nep-inhibitors, inhibitors of the endogenous endothelin producing system and at1-receptor antagonists |
| EP1827448A1 (en) | 2004-12-15 | 2007-09-05 | Solvay Pharmaceuticals GmbH | Pharmaceutical compositions comprising nep-inhibitors, inhibitors of the endogenous endothelin producing system and hmg coa reductase inhibitors |
| DE602006013792D1 (de) * | 2005-02-18 | 2010-06-02 | Solvay Pharm Gmbh | Pharmazeutische zusammensetzungen mit nep-inhibitoren, inhibitoren des endogenes endothelin produzierenden systems und diuretika |
| CA2681267C (en) * | 2007-04-13 | 2013-11-19 | Southern Research Institute | Anti-angiogenic agents and methods of use |
| AR071375A1 (es) * | 2008-04-22 | 2010-06-16 | Solvay Pharm Gmbh | Formulaciones para ingredientes farmaceuticos activos de permeabilidad deficiente, proceso de preparacion y producto |
| PL424452A1 (pl) * | 2018-01-31 | 2019-08-12 | Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością | Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08269001A (ja) * | 1995-01-28 | 1996-10-15 | Merck Patent Gmbh | ４−アミノベンゾイルグアニジン誘導体 |
| JPH11292886A (ja) * | 1997-11-12 | 1999-10-26 | Solvay Pharmaceut Gmbh | ホスホン酸で置換されたベンズアゼピノン−ｎ−酢酸誘導体、並びにその製法及びこの化合物を含有する薬剤 |
| JP2002537258A (ja) * | 1999-02-16 | 2002-11-05 | ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 高血圧の治療のための医薬 |
| WO2003059939A1 (en) * | 2002-01-16 | 2003-07-24 | Solvay Pharmaceuticals B.V. | Solid salts benzazepine compounds and their use in the preparation of pharmaceuticals compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19510566A1 (de) * | 1995-03-23 | 1996-09-26 | Kali Chemie Pharma Gmbh | Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
-
2004
- 2004-09-12 SA SA04250283A patent/SA04250283B1/ar unknown
- 2004-09-22 TW TW093128652A patent/TWI332947B/zh active
- 2004-09-22 AR ARP040103409A patent/AR045798A1/es not_active Application Discontinuation
- 2004-09-23 MX MXPA06003226A patent/MXPA06003226A/es active IP Right Grant
- 2004-09-23 EP EP04766846A patent/EP1670814A1/en not_active Withdrawn
- 2004-09-23 BR BRPI0414744-8A patent/BRPI0414744A/pt not_active IP Right Cessation
- 2004-09-23 CA CA002539895A patent/CA2539895A1/en not_active Abandoned
- 2004-09-23 JP JP2006527420A patent/JP4824562B2/ja not_active Expired - Fee Related
- 2004-09-23 AU AU2004276002A patent/AU2004276002B2/en not_active Ceased
- 2004-09-23 WO PCT/EP2004/052289 patent/WO2005030795A1/en active Application Filing
- 2004-09-23 RU RU2006113946/04A patent/RU2368601C2/ru not_active IP Right Cessation
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2006
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- 2006-03-24 KR KR1020067005869A patent/KR101264934B1/ko not_active IP Right Cessation
- 2006-04-25 NO NO20061821A patent/NO20061821L/no not_active Application Discontinuation
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2007
- 2007-03-30 HK HK07103455.5A patent/HK1096105A1/xx not_active IP Right Cessation
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08269001A (ja) * | 1995-01-28 | 1996-10-15 | Merck Patent Gmbh | ４−アミノベンゾイルグアニジン誘導体 |
| JPH11292886A (ja) * | 1997-11-12 | 1999-10-26 | Solvay Pharmaceut Gmbh | ホスホン酸で置換されたベンズアゼピノン−ｎ−酢酸誘導体、並びにその製法及びこの化合物を含有する薬剤 |
| JP2002537258A (ja) * | 1999-02-16 | 2002-11-05 | ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 高血圧の治療のための医薬 |
| WO2003059939A1 (en) * | 2002-01-16 | 2003-07-24 | Solvay Pharmaceuticals B.V. | Solid salts benzazepine compounds and their use in the preparation of pharmaceuticals compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| AR045798A1 (es) | 2005-11-16 |
| JP2007535482A (ja) | 2007-12-06 |
| RU2368601C2 (ru) | 2009-09-27 |
| WO2005030795A1 (en) | 2005-04-07 |
| CA2539895A1 (en) | 2005-04-07 |
| AU2004276002A1 (en) | 2005-04-07 |
| IL174373A0 (en) | 2006-08-01 |
| KR101264934B1 (ko) | 2013-05-20 |
| HK1096105A1 (en) | 2007-05-25 |
| MXPA06003226A (es) | 2006-05-22 |
| BRPI0414744A (pt) | 2006-11-21 |
| NO20061821L (no) | 2006-06-22 |
| SA04250283B1 (ar) | 2008-05-26 |
| RU2006113946A (ru) | 2007-11-10 |
| TWI332947B (en) | 2010-11-11 |
| TW200524874A (en) | 2005-08-01 |
| EP1670814A1 (en) | 2006-06-21 |
| IL174373A (en) | 2011-12-29 |
| KR20060101460A (ko) | 2006-09-25 |
| AU2004276002B2 (en) | 2010-07-22 |
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