JP4795021B2 - 敗血症治療における経口用ラクトフェリン - Google Patents

敗血症治療における経口用ラクトフェリン Download PDF

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Publication number
JP4795021B2
JP4795021B2 JP2005508468A JP2005508468A JP4795021B2 JP 4795021 B2 JP4795021 B2 JP 4795021B2 JP 2005508468 A JP2005508468 A JP 2005508468A JP 2005508468 A JP2005508468 A JP 2005508468A JP 4795021 B2 JP4795021 B2 JP 4795021B2
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lactoferrin
composition
sepsis
rhlf
administered
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Japanese (ja)
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JP2006514111A (ja
JP2006514111A5 (https=
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バラダカーリ、アトゥル
ペトラーク、カレル
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エイジェニックス インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2005508468A 2002-12-06 2003-12-05 敗血症治療における経口用ラクトフェリン Expired - Fee Related JP4795021B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US43139302P 2002-12-06 2002-12-06
US60/431,393 2002-12-06
US49832703P 2003-08-27 2003-08-27
US60/498,327 2003-08-27
PCT/US2003/038621 WO2004052281A2 (en) 2002-12-06 2003-12-05 Oral lactoferrin in the treatment of sepsis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010265361A Division JP2011068666A (ja) 2002-12-06 2010-11-29 敗血症治療における経口用ラクトフェリン

Publications (3)

Publication Number Publication Date
JP2006514111A JP2006514111A (ja) 2006-04-27
JP2006514111A5 JP2006514111A5 (https=) 2006-11-24
JP4795021B2 true JP4795021B2 (ja) 2011-10-19

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Family Applications (2)

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JP2005508468A Expired - Fee Related JP4795021B2 (ja) 2002-12-06 2003-12-05 敗血症治療における経口用ラクトフェリン
JP2010265361A Pending JP2011068666A (ja) 2002-12-06 2010-11-29 敗血症治療における経口用ラクトフェリン

Family Applications After (1)

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JP2010265361A Pending JP2011068666A (ja) 2002-12-06 2010-11-29 敗血症治療における経口用ラクトフェリン

Country Status (6)

Country Link
US (2) US20040152624A1 (https=)
EP (1) EP1581243A4 (https=)
JP (2) JP4795021B2 (https=)
AU (2) AU2003298906A1 (https=)
CA (1) CA2508912A1 (https=)
WO (1) WO2004052281A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022145536A1 (ko) * 2020-12-30 2022-07-07 경상대학교병원 급성 호흡 곤란 증후군 환자의 예후 예측을 위한 정보제공방법

Families Citing this family (15)

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US6399570B1 (en) * 1999-02-05 2002-06-04 Agennix, Inc. Antimicrobial/endotoxin neutralizing polypeptide
DE60335997D1 (de) 2002-09-16 2011-03-24 Agennix Inc Lactoferrin-zusammensetzungen und verfahren zur behandlung von diabetischen ulcus
CA2508912A1 (en) * 2002-12-06 2004-06-24 Agennix Incorporated Oral lactoferrin in the treatment of sepsis
AU2003296447A1 (en) 2002-12-10 2004-06-30 Agennix Incorporated Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
US8105615B2 (en) * 2003-06-06 2012-01-31 Agennix Incorporated Lactoferrin as an adjuvant in cancer vaccines
WO2006047744A2 (en) * 2004-10-26 2006-05-04 Agennix Incorporated Compositions of lactoferrin related peptides and uses thereof
ITMI20052351A1 (it) * 2005-12-09 2007-06-10 Microbo Srl Nuovo uso farmaceutico delle transferrine e composizioni farmaceutiche derivate
WO2007109681A2 (en) * 2006-03-20 2007-09-27 Glanbia Nutritionals (Ireland) Limited Compositions and methods for enhancing vasodilation
JP5087297B2 (ja) * 2007-03-05 2012-12-05 森永乳業株式会社 インターロイキン−１１産生促進剤
ITRM20080163A1 (it) * 2008-03-26 2009-09-27 Maurizio Acri Uso della lattoferrina per la prevenzione delle sepsi neonatali in neonati prematuri
US20130225477A1 (en) 2010-02-25 2013-08-29 Agennix Ag Oral Lactoferrin in the Treatment of Severe Sepsis
CN101829075B (zh) * 2010-04-27 2011-07-20 中国人民解放军第三军医大学第一附属医院 苦柯胺a和苦柯胺b的用途
EP3017824B1 (en) * 2013-04-09 2019-06-05 The University of Tokyo Inhibitor of extracellular trap formation in leukocytes
US20230149515A1 (en) * 2020-04-29 2023-05-18 The Regents Of The University Of Michigan Inhibition of sars-cov-2 viral entry through oral administration of lactoferrin and uses thereof
WO2023178060A1 (en) * 2022-03-14 2023-09-21 The Children's Mercy Hospital Prophylaxis of neonatal escherichia coli sepsis

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JPH08165248A (ja) * 1994-12-15 1996-06-25 Nobuo Kuriiwa エンドトキシンによる炎症の抑止剤
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JP2002541066A (ja) * 1999-02-05 2002-12-03 エンドゲン・リサーチ・ペーハー・アクチボラゲット 抗微生物薬／エンドトキシンを中和するポリペプチド

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DE60335997D1 (de) * 2002-09-16 2011-03-24 Agennix Inc Lactoferrin-zusammensetzungen und verfahren zur behandlung von diabetischen ulcus
AU2003291206A1 (en) * 2002-12-04 2004-06-23 Agennix Incorporated Lactoferrin in the reduction of circulating cholesterol, vascular inflammation, atherosclerosis and cardiovascular disease
CA2508912A1 (en) * 2002-12-06 2004-06-24 Agennix Incorporated Oral lactoferrin in the treatment of sepsis
AU2003296447A1 (en) * 2002-12-10 2004-06-30 Agennix Incorporated Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
AU2003293500A1 (en) * 2002-12-12 2004-07-09 Agennix Incorporated Lactoferrin in the reduction of pain
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JPH0873499A (ja) * 1994-09-01 1996-03-19 Snow Brand Milk Prod Co Ltd 新規ペプチドおよび免疫賦活剤
JPH08165248A (ja) * 1994-12-15 1996-06-25 Nobuo Kuriiwa エンドトキシンによる炎症の抑止剤
JP2002515893A (ja) * 1997-02-03 2002-05-28 ファーミング インテレクチュアル プロパティ ビーブイ ヒトラクトフェリンおよびその改変体の有用な特性
JP2002541066A (ja) * 1999-02-05 2002-12-03 エンドゲン・リサーチ・ペーハー・アクチボラゲット 抗微生物薬／エンドトキシンを中和するポリペプチド
WO2001051079A1 (en) * 2000-01-14 2001-07-19 Meiji Dairies Corporation Antigen-specific ige antibody production inhibitors
JP2001333737A (ja) * 2000-03-24 2001-12-04 Meiji Milk Prod Co Ltd グラム陰性菌のリピドａに対する特異的抗体産生を誘導する組成物。

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022145536A1 (ko) * 2020-12-30 2022-07-07 경상대학교병원 급성 호흡 곤란 증후군 환자의 예후 예측을 위한 정보제공방법

Also Published As

Publication number Publication date
JP2011068666A (ja) 2011-04-07
EP1581243A2 (en) 2005-10-05
AU2003298906A1 (en) 2004-06-30
WO2004052281A2 (en) 2004-06-24
AU2010200210A1 (en) 2010-02-11
US20100210510A1 (en) 2010-08-19
CA2508912A1 (en) 2004-06-24
JP2006514111A (ja) 2006-04-27
WO2004052281A3 (en) 2004-09-10
US20040152624A1 (en) 2004-08-05
EP1581243A4 (en) 2008-01-02

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