JP4741510B2 - 分岐ペプチド両親媒性物質、関連するエピトープ化合物およびその自己集合構造物 - Google Patents

分岐ペプチド両親媒性物質、関連するエピトープ化合物およびその自己集合構造物 Download PDF

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JP4741510B2
JP4741510B2 JP2006542793A JP2006542793A JP4741510B2 JP 4741510 B2 JP4741510 B2 JP 4741510B2 JP 2006542793 A JP2006542793 A JP 2006542793A JP 2006542793 A JP2006542793 A JP 2006542793A JP 4741510 B2 JP4741510 B2 JP 4741510B2
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peptide
compound
component
epitope
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JP2007535493A5 (https=
JP2007535493A (ja
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サミュエル アイ． スタップ
マスタファ オー． グーラー
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Northwestern University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/641—Branched, dendritic or hypercomb peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
JP2006542793A 2003-12-05 2004-12-06 分岐ペプチド両親媒性物質、関連するエピトープ化合物およびその自己集合構造物 Expired - Fee Related JP4741510B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52744203P 2003-12-05 2003-12-05
US60/527,442 2003-12-05
PCT/US2004/040546 WO2005056576A2 (en) 2003-12-05 2004-12-06 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof

Publications (3)

Publication Number Publication Date
JP2007535493A JP2007535493A (ja) 2007-12-06
JP2007535493A5 JP2007535493A5 (https=) 2008-06-26
JP4741510B2 true JP4741510B2 (ja) 2011-08-03

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JP2006542793A Expired - Fee Related JP4741510B2 (ja) 2003-12-05 2004-12-06 分岐ペプチド両親媒性物質、関連するエピトープ化合物およびその自己集合構造物

Country Status (9)

Country Link
US (1) US7452679B2 (https=)
EP (1) EP1696944A4 (https=)
JP (1) JP4741510B2 (https=)
KR (1) KR20070004561A (https=)
CN (1) CN1905893A (https=)
AU (1) AU2004297211A1 (https=)
CA (1) CA2549391A1 (https=)
MX (1) MXPA06006387A (https=)
WO (1) WO2005056576A2 (https=)

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Publication number Publication date
WO2005056576A2 (en) 2005-06-23
EP1696944A2 (en) 2006-09-06
US7452679B2 (en) 2008-11-18
CN1905893A (zh) 2007-01-31
KR20070004561A (ko) 2007-01-09
AU2004297211A1 (en) 2005-06-23
EP1696944A4 (en) 2008-11-05
MXPA06006387A (es) 2006-09-04
CA2549391A1 (en) 2005-06-23
WO2005056576A3 (en) 2006-01-19
US20050208589A1 (en) 2005-09-22
JP2007535493A (ja) 2007-12-06

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