JP4706785B2 - 経口投与用粒子状医薬組成物 - Google Patents

経口投与用粒子状医薬組成物 Download PDF

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Publication number
JP4706785B2
JP4706785B2 JP2009222020A JP2009222020A JP4706785B2 JP 4706785 B2 JP4706785 B2 JP 4706785B2 JP 2009222020 A JP2009222020 A JP 2009222020A JP 2009222020 A JP2009222020 A JP 2009222020A JP 4706785 B2 JP4706785 B2 JP 4706785B2
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Prior art keywords
pharmaceutical composition
orally disintegrating
drug
water
disintegrating tablet
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Expired - Fee Related
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JP2009222020A
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Japanese (ja)
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JP2010083886A (ja
JP2010083886A5 (enExample
Inventor
弘朗 田崎
篤 真栄田
武史 矢野
和博 迫
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Astellas Pharma Inc
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Astellas Pharma Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009222020A 2008-09-30 2009-09-28 経口投与用粒子状医薬組成物 Expired - Fee Related JP4706785B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10137908P 2008-09-30 2008-09-30
US10139408P 2008-09-30 2008-09-30
US61/101,394 2008-09-30
US61/101,379 2008-09-30

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010188328A Division JP5282772B2 (ja) 2008-09-30 2010-08-25 経口投与用粒子状医薬組成物

Publications (3)

Publication Number Publication Date
JP2010083886A JP2010083886A (ja) 2010-04-15
JP2010083886A5 JP2010083886A5 (enExample) 2010-10-07
JP4706785B2 true JP4706785B2 (ja) 2011-06-22

Family

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Family Applications (2)

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JP2009222020A Expired - Fee Related JP4706785B2 (ja) 2008-09-30 2009-09-28 経口投与用粒子状医薬組成物
JP2010188328A Expired - Fee Related JP5282772B2 (ja) 2008-09-30 2010-08-25 経口投与用粒子状医薬組成物

Family Applications After (1)

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JP2010188328A Expired - Fee Related JP5282772B2 (ja) 2008-09-30 2010-08-25 経口投与用粒子状医薬組成物

Country Status (3)

Country Link
US (1) US20100136110A1 (enExample)
JP (2) JP4706785B2 (enExample)
WO (1) WO2010038691A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5506415B2 (ja) * 2010-01-13 2014-05-28 東和薬品株式会社 ＨＭＧ−ＣｏＡレダクターゼ阻害剤含有経口固形製剤
WO2011121824A1 (ja) * 2010-03-29 2011-10-06 アステラス製薬株式会社 口腔内崩壊錠
JP5614445B2 (ja) * 2010-03-29 2014-10-29 アステラス製薬株式会社 経口投与用粒子状医薬組成物
JP6073543B2 (ja) * 2010-07-08 2017-02-01 沢井製薬株式会社 ロラタジン含有口腔内崩壊錠の製造方法
WO2012056509A1 (ja) * 2010-10-25 2012-05-03 興和株式会社 医薬組成物
EP2500013B1 (en) * 2011-03-15 2019-10-02 Alfred E. Tiefenbacher (GmbH & Co. KG) Pharmaceutical composition comprising solifenacin
EP2709593A4 (en) * 2011-05-16 2014-10-29 Sun Pharma Advanced Res Co Ltd PHARMACEUTICAL COMPOSITION OF MULTIPLE PARTICLES
FI126168B (en) 2012-09-18 2016-07-29 Novaldmedical Ltd Oy A method for coating pharmaceutical substrates
MX392839B (es) * 2012-11-30 2025-03-24 Acura Pharmaceuticals Inc Liberacion autorregulada de ingrediente farmaceutico activo.
CN104042628B (zh) * 2013-03-15 2017-04-12 复旦大学 氢氧化铝在制备治疗肝癌药物中的应用
EP2979697A4 (en) * 2013-03-26 2016-11-30 Kissei Pharmaceutical PREPARATION FOR ORAL ADMINISTRATION WITH MASKED BITTERNITY OF SILODOSINE
CN105611915B (zh) * 2013-08-14 2021-05-11 赢创运营有限公司 包衣组合物
JP6344678B2 (ja) * 2013-09-27 2018-06-20 キョーリンリメディオ株式会社 テルミサルタン含有製剤及びその製造方法
WO2017115764A1 (ja) * 2015-12-28 2017-07-06 日本新薬株式会社 圧縮成型製剤
EP3419659A1 (en) 2016-02-23 2019-01-02 The Regents of the University of Colorado, A Body Corporate Compositions and methods for making and using thermostable immunogenic formulations with increased compatibility of use as vaccines against one or more pathogens
EP3421032A4 (en) * 2016-02-23 2019-10-23 Nipro Corporation PARTICULARS OF A PHARMACEUTICAL COMPOSITION, ORAL DECOMPOSITION PREPARATION THEREOF AND METHOD FOR PRODUCING PARTICLES OF A PHARMACEUTICAL COMPOSITION
DK3429559T3 (da) * 2016-03-15 2022-07-11 Acer Therapeutics Inc Velsmagende sammensætninger indeholdende natriumphenylbutyrat og anvendelser deraf
WO2018065826A1 (en) * 2016-10-06 2018-04-12 Sucampo Ag Multilayer beads for pharmaceutical use
US11696895B2 (en) 2017-12-28 2023-07-11 Sumitomo Pharma Co., Ltd. Fine particle coating (drug-containing hollow particle and method for manufacturing same)
KR102496427B1 (ko) 2018-01-16 2023-02-06 어플라이드 머티어리얼스, 인코포레이티드 금속 산화물로 캡슐화된 약물 조성물들 및 그의 제조 방법들
JP2022545279A (ja) * 2019-08-27 2022-10-26 アプライド マテリアルズ インコーポレイテッド 医薬品の溶解度制御のための気相コーティング
TWI870622B (zh) 2020-10-02 2025-01-21 美商應用材料股份有限公司 製備氧化矽塗佈藥品的低溫處理
WO2023056304A1 (en) 2021-09-30 2023-04-06 Applied Materials, Inc. Low temperature silicon oxide coating for pharmaceutical applications

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759499B2 (ja) * 1984-02-10 1995-06-28 ベンツォン ファーマ エイ／エス 拡散被覆された複合単位服用剤
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US5576014A (en) * 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
JPH08333242A (ja) * 1995-06-09 1996-12-17 Tanabe Seiyaku Co Ltd 圧縮成型製剤
DK0941075T3 (da) * 1997-01-06 2003-07-14 Pfizer Smagsmaskerende farmaceutisk doseringsform med hurtig frigivelse
JP2000273037A (ja) * 1999-03-19 2000-10-03 Kyoto Pharmaceutical Industries Ltd 解熱・鎮痛チュアブル錠およびその製造法
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
AU2005237360B2 (en) * 2004-04-30 2010-10-21 Astellas Pharma Inc. Time-limited release type granular pharmaceutical composition for oral administration and intraoral rapid disintegration tablet containing the composition
JP2007211006A (ja) * 2006-01-16 2007-08-23 Ono Pharmaceut Co Ltd 溶出安定性を有するコーティング固形製剤
JP2009530367A (ja) * 2006-03-24 2009-08-27 パナセア バイオテック リミテッド 調節放出性抗生組成物およびその製造方法
CL2007001194A1 (es) * 2006-04-27 2008-01-04 Takeda Pharmaceutical Preparacion farmaceutica solida que comprende particulas que comprenden (i) particulas de nucleo con excipiente y (ii) pioglitazona o una sal de la misma y un polimero soluble en acido, como copolimero de aminoalquil metacrilato e o dietilaminoacetato de polivinilacetal, ambos recubriendo el nucleo
JP5332615B2 (ja) * 2006-09-14 2013-11-06 アステラス製薬株式会社 口腔内崩壊錠及びその製造法

Also Published As

Publication number Publication date
JP5282772B2 (ja) 2013-09-04
JP2010083886A (ja) 2010-04-15
JP2010265325A (ja) 2010-11-25
WO2010038691A1 (ja) 2010-04-08
US20100136110A1 (en) 2010-06-03

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