JP4592284B2 - 髄膜炎菌付着因子 - Google Patents

髄膜炎菌付着因子 Download PDF

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Publication number
JP4592284B2
JP4592284B2 JP2003515553A JP2003515553A JP4592284B2 JP 4592284 B2 JP4592284 B2 JP 4592284B2 JP 2003515553 A JP2003515553 A JP 2003515553A JP 2003515553 A JP2003515553 A JP 2003515553A JP 4592284 B2 JP4592284 B2 JP 4592284B2
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Prior art keywords
nada
app
protein
cells
coli
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2003515553A
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English (en)
Japanese (ja)
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JP2005503785A (ja
Inventor
マリア アリコ，
マウリツィオ コマンデュッチ，
Original Assignee
カイロン ソチエタ ア レスポンサビリタ リミタータ
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Priority claimed from GB0118401A external-priority patent/GB0118401D0/en
Priority claimed from GBGB0121591.2A external-priority patent/GB0121591D0/en
Priority claimed from GB0211025A external-priority patent/GB0211025D0/en
Application filed by カイロン ソチエタ ア レスポンサビリタ リミタータ filed Critical カイロン ソチエタ ア レスポンサビリタ リミタータ
Publication of JP2005503785A publication Critical patent/JP2005503785A/ja
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Publication of JP4592284B2 publication Critical patent/JP4592284B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2003515553A 2001-07-27 2002-07-26 髄膜炎菌付着因子 Expired - Fee Related JP4592284B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0118401A GB0118401D0 (en) 2001-07-27 2001-07-27 Meningococcus data
GBGB0121591.2A GB0121591D0 (en) 2001-09-06 2001-09-06 Hybrid and tandem expression of neisserial proteins
GB0211025A GB0211025D0 (en) 2002-05-14 2002-05-14 Meningococcus adhesins
PCT/IB2002/003396 WO2003010194A2 (en) 2001-07-27 2002-07-26 Meningococcus adhesins nada, app and orf 40

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2009033304A Division JP4902678B2 (ja) 2001-07-27 2009-02-16 髄膜炎菌付着因子
JP2010148240A Division JP2010268801A (ja) 2001-07-27 2010-06-29 髄膜炎菌付着因子

Publications (2)

Publication Number Publication Date
JP2005503785A JP2005503785A (ja) 2005-02-10
JP4592284B2 true JP4592284B2 (ja) 2010-12-01

Family

ID=27256234

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2003515553A Expired - Fee Related JP4592284B2 (ja) 2001-07-27 2002-07-26 髄膜炎菌付着因子
JP2009033304A Expired - Lifetime JP4902678B2 (ja) 2001-07-27 2009-02-16 髄膜炎菌付着因子
JP2010148240A Withdrawn JP2010268801A (ja) 2001-07-27 2010-06-29 髄膜炎菌付着因子

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009033304A Expired - Lifetime JP4902678B2 (ja) 2001-07-27 2009-02-16 髄膜炎菌付着因子
JP2010148240A Withdrawn JP2010268801A (ja) 2001-07-27 2010-06-29 髄膜炎菌付着因子

Country Status (14)

Country Link
US (3) US20050232936A1 (de)
EP (2) EP1412381B1 (de)
JP (3) JP4592284B2 (de)
AT (1) ATE469915T1 (de)
AU (1) AU2002355197A1 (de)
BR (1) BR0211494A (de)
CA (1) CA2452836C (de)
CY (2) CY1111715T1 (de)
DE (1) DE60236596D1 (de)
DK (1) DK2248822T3 (de)
ES (1) ES2615362T3 (de)
MX (1) MXPA04000653A (de)
PT (1) PT2248822T (de)
WO (1) WO2003010194A2 (de)

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* Cited by examiner, † Cited by third party
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GB9808866D0 (en) * 1998-04-24 1998-06-24 Smithkline Beecham Biolog Novel compounds
EP2261352A3 (de) 1998-05-01 2012-01-04 Novartis Vaccines and Diagnostics, Inc. Antigene und Zusammensetzungen gegen Neisseria meningitidis
JP2003518363A (ja) 1999-04-30 2003-06-10 カイロン エセ．ピー．アー． 保存されたナイセリア抗原
EP2270173B1 (de) * 1999-05-19 2016-01-06 GlaxoSmithKline Biologicals SA Neisseria Kombinationzusammensetzungen
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
ES2281409T3 (es) 2000-02-28 2007-10-01 Novartis Vaccines And Diagnostics S.R.L. Expresion heterologa de proteinas de neisseria.
US6936261B2 (en) 2000-07-27 2005-08-30 Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
BR0211494A (pt) 2001-07-27 2004-08-17 Chiron Srl Adesinas de meningococo nada, app e orf 40
EP1524991A1 (de) * 2002-08-02 2005-04-27 GlaxoSmithKline Biologicals S.A. Impfstoffzusammensetzung die transferrin bindende protein und hsf aus gram-negativen bakterien enthält
HUE031886T2 (en) * 2002-10-11 2017-08-28 Glaxosmithkline Biologicals Sa Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
ES2461350T3 (es) 2003-01-30 2014-05-19 Novartis Ag Vacunas inyectables contra múltiples serogrupos de meningococos
GB0315022D0 (en) * 2003-06-26 2003-07-30 Chiron Srl Virulence-associated adhesins
CN103357002A (zh) 2003-10-02 2013-10-23 诺华疫苗和诊断有限公司 多种脑膜炎球菌血清群的液体疫苗
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0415160D0 (en) * 2004-07-06 2004-08-11 Chiron Srl Inhibitors of bacterial infection
ES2616294T3 (es) 2005-01-27 2017-06-12 Children's Hospital & Research Center At Oakland Vacunas de vesículas basadas en GNA1870 para protección de amplio espectro contra enfermedades provocadas por Neisseria meningitidis
WO2007066226A2 (en) * 2005-12-06 2007-06-14 Universita Degli Studi Di Padova Methods and compositions relating to adhesins as adjuvants
MX2011003381A (es) * 2008-09-30 2011-04-21 Abbott Lab Metodo mejorado para despliegue de arn.
WO2011008400A2 (en) 2009-06-16 2011-01-20 Novartis Ag High-throughput complement-mediated antibody-dependent and opsonic bactericidal assays
BR112013005626B1 (pt) * 2010-09-10 2022-07-26 Glaxosmithkline Biologicals Sa Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
MX357538B (es) 2012-06-14 2018-07-13 Novartis Ag Vacunas para meningococo de serogrupo x.
AU2013295242C1 (en) 2012-07-27 2018-08-09 Institut National De La Sante Et De La Recherche Medicale CD147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
TW201620927A (zh) * 2014-02-24 2016-06-16 葛蘭素史密斯克藍生物品公司 Ｕｓｐａ２蛋白質構築體及其用途
EP3263695A1 (de) 2016-06-29 2018-01-03 GlaxoSmithKline Biologicals SA Immunogene zusammensetzungen
GB202115151D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Methods
CN119487052A (zh) * 2022-03-31 2025-02-18 昆士兰大学 改进的嵌合多肽及其用途

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BR0211494A (pt) 2001-07-27 2004-08-17 Chiron Srl Adesinas de meningococo nada, app e orf 40
EP1524991A1 (de) 2002-08-02 2005-04-27 GlaxoSmithKline Biologicals S.A. Impfstoffzusammensetzung die transferrin bindende protein und hsf aus gram-negativen bakterien enthält
HUE031886T2 (en) 2002-10-11 2017-08-28 Glaxosmithkline Biologicals Sa Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
ES2461350T3 (es) * 2003-01-30 2014-05-19 Novartis Ag Vacunas inyectables contra múltiples serogrupos de meningococos
CN103357002A (zh) * 2003-10-02 2013-10-23 诺华疫苗和诊断有限公司 多种脑膜炎球菌血清群的液体疫苗

Also Published As

Publication number Publication date
EP2248822B1 (de) 2016-11-23
JP4902678B2 (ja) 2012-03-21
AU2002355197A1 (en) 2003-02-17
US20140294884A1 (en) 2014-10-02
ATE469915T1 (de) 2010-06-15
EP2248822A3 (de) 2011-04-13
CY1111715T1 (el) 2015-10-07
EP1412381A2 (de) 2004-04-28
ES2615362T3 (es) 2017-06-06
WO2003010194A2 (en) 2003-02-06
CA2452836C (en) 2012-11-27
DK2248822T3 (en) 2017-02-13
BR0211494A (pt) 2004-08-17
MXPA04000653A (es) 2004-11-22
DE60236596D1 (de) 2010-07-15
CA2452836A1 (en) 2003-02-06
EP1412381B1 (de) 2010-06-02
WO2003010194A3 (en) 2003-10-02
JP2005503785A (ja) 2005-02-10
US20100221256A1 (en) 2010-09-02
JP2009148279A (ja) 2009-07-09
PT2248822T (pt) 2017-02-14
JP2010268801A (ja) 2010-12-02
US20050232936A1 (en) 2005-10-20
US9249197B2 (en) 2016-02-02
CY1118628T1 (el) 2017-07-12
EP2248822A2 (de) 2010-11-10

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