JP4573925B2 - 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用 - Google Patents

新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用 Download PDF

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Publication number
JP4573925B2
JP4573925B2 JP19279099A JP19279099A JP4573925B2 JP 4573925 B2 JP4573925 B2 JP 4573925B2 JP 19279099 A JP19279099 A JP 19279099A JP 19279099 A JP19279099 A JP 19279099A JP 4573925 B2 JP4573925 B2 JP 4573925B2
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JP
Japan
Prior art keywords
methyl
dideoxy
formula
erythromycin
ribohexopyranosyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP19279099A
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English (en)
Japanese (ja)
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JP2000026494A (ja
JP2000026494A5 (enExample
Inventor
アレクシー・ドニ
ジウゼッペ・ジグリオッティ
Original Assignee
アベンティス・ファーマ・ソシエテ・アノニム
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Filing date
Publication date
Priority claimed from FR9808795A external-priority patent/FR2780977B1/fr
Priority claimed from FR9905245A external-priority patent/FR2792637B1/fr
Application filed by アベンティス・ファーマ・ソシエテ・アノニム filed Critical アベンティス・ファーマ・ソシエテ・アノニム
Publication of JP2000026494A publication Critical patent/JP2000026494A/ja
Publication of JP2000026494A5 publication Critical patent/JP2000026494A5/ja
Application granted granted Critical
Publication of JP4573925B2 publication Critical patent/JP4573925B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP19279099A 1998-07-09 1999-07-07 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用 Expired - Lifetime JP4573925B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9808795A FR2780977B1 (fr) 1998-07-09 1998-07-09 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR9808795 1998-07-09
FR9905245 1999-04-26
FR9905245A FR2792637B1 (fr) 1999-04-26 1999-04-26 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (3)

Publication Number Publication Date
JP2000026494A JP2000026494A (ja) 2000-01-25
JP2000026494A5 JP2000026494A5 (enExample) 2006-06-22
JP4573925B2 true JP4573925B2 (ja) 2010-11-04

Family

ID=26234434

Family Applications (1)

Application Number Title Priority Date Filing Date
JP19279099A Expired - Lifetime JP4573925B2 (ja) 1998-07-09 1999-07-07 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用

Country Status (8)

Country Link
US (1) US6433151B1 (enExample)
EP (1) EP0974598B1 (enExample)
JP (1) JP4573925B2 (enExample)
AT (1) ATE521619T1 (enExample)
CY (1) CY1112087T1 (enExample)
DK (1) DK0974598T3 (enExample)
ES (1) ES2372156T3 (enExample)
PT (1) PT974598E (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE344269T1 (de) * 1998-12-10 2006-11-15 Pfizer Prod Inc Carbamat und carbazat ketolid antibiotika
US20080287376A1 (en) * 2004-07-28 2008-11-20 Mohammad Salman Ketolide Derivatives as Antibacterial Agents
EP1812455A2 (en) * 2004-09-27 2007-08-01 Ranbaxy Laboratories Limited Erythromycin a derivatives as antibacterial agents
EP1807439A2 (en) * 2004-10-25 2007-07-18 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
HRP20100253T1 (hr) * 2004-12-21 2010-06-30 Pfizer Products Inc. Makrolidi
EP1957085A2 (en) * 2005-11-08 2008-08-20 Ranbaxy Laboratories, Ltd. Macrolides as anti-inflammatory agents
EP1954294A2 (en) * 2005-11-23 2008-08-13 Ranbaxy Laboratories Limited Use of macrolide derivatives for treating acne
EP1960413A2 (en) * 2005-11-23 2008-08-27 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
WO2007060518A2 (en) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
CA2669818A1 (en) * 2006-12-12 2008-06-19 Zambon S.P.A. Macrolide compounds endowed with antiinflammatory activity
CN113573715A (zh) * 2018-12-17 2021-10-29 卢内拉生物技术有限公司 用于靶向线粒体和杀死癌症干细胞的三联疗法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725385A (en) * 1970-11-02 1973-04-03 Abbott Lab Process for the demethylation of 3-amino macrolides
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
WO1997017356A1 (en) * 1995-11-08 1997-05-15 Abbott Laboratories Tricyclic erythromycin derivatives
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745290B1 (fr) * 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
IL128681A0 (en) 1996-09-04 2000-01-31 Abbott Lab 6-O substituted ketolides having antibacterial activity
PL339575A1 (en) * 1997-09-30 2000-12-18 Abbott Lab 3'-n-modified, 6-o-substituted ketolydic derivatives of erythromycin exhibiting antibacterial activity

Also Published As

Publication number Publication date
US6433151B1 (en) 2002-08-13
JP2000026494A (ja) 2000-01-25
ATE521619T1 (de) 2011-09-15
PT974598E (pt) 2011-11-23
EP0974598B1 (fr) 2011-08-24
EP0974598A3 (fr) 2003-12-17
DK0974598T3 (da) 2011-12-19
ES2372156T3 (es) 2012-01-16
EP0974598A2 (fr) 2000-01-26
CY1112087T1 (el) 2015-11-04

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