JP4514338B2 - 造血幹細胞の濃縮に特化した血液分離装置 - Google Patents
造血幹細胞の濃縮に特化した血液分離装置 Download PDFInfo
- Publication number
- JP4514338B2 JP4514338B2 JP2000590712A JP2000590712A JP4514338B2 JP 4514338 B2 JP4514338 B2 JP 4514338B2 JP 2000590712 A JP2000590712 A JP 2000590712A JP 2000590712 A JP2000590712 A JP 2000590712A JP 4514338 B2 JP4514338 B2 JP 4514338B2
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- JP
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- Prior art keywords
- chamber
- fluid
- processing chamber
- biological fluid
- piston
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000926 separation method Methods 0.000 title claims abstract description 43
- 210000004369 blood Anatomy 0.000 title claims abstract description 20
- 239000008280 blood Substances 0.000 title claims abstract description 20
- 210000003958 hematopoietic stem cell Anatomy 0.000 title claims description 9
- 238000012545 processing Methods 0.000 claims abstract description 73
- 210000000130 stem cell Anatomy 0.000 claims abstract description 43
- 239000013060 biological fluid Substances 0.000 claims abstract description 36
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- 239000000306 component Substances 0.000 claims description 36
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- 210000004700 fetal blood Anatomy 0.000 claims description 17
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- 210000001185 bone marrow Anatomy 0.000 claims description 2
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- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
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- RSGFPIWWSCWCFJ-VAXZQHAWSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal;phosphoric acid Chemical compound OP(O)(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O.OC(=O)CC(O)(C(O)=O)CC(O)=O RSGFPIWWSCWCFJ-VAXZQHAWSA-N 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3698—Expressing processed fluid out from the turning rotor using another fluid compressing the treatment chamber; Variable volume rotors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/0485—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
- Centrifugal Separators (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB9802114 | 1998-12-24 | ||
| IB9802114 | 1998-12-24 | ||
| PCT/IB1999/002053 WO2000038762A1 (en) | 1998-12-24 | 1999-12-24 | Blood separation system particularly for concentrating hematopoietic stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002533171A JP2002533171A (ja) | 2002-10-08 |
| JP2002533171A5 JP2002533171A5 (https=) | 2009-12-03 |
| JP4514338B2 true JP4514338B2 (ja) | 2010-07-28 |
Family
ID=11004802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000590712A Expired - Lifetime JP4514338B2 (ja) | 1998-12-24 | 1999-12-24 | 造血幹細胞の濃縮に特化した血液分離装置 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6733433B1 (https=) |
| EP (1) | EP1144026B1 (https=) |
| JP (1) | JP4514338B2 (https=) |
| CN (1) | CN1182882C (https=) |
| AT (1) | ATE271890T1 (https=) |
| AU (1) | AU1675600A (https=) |
| DE (1) | DE69919029T2 (https=) |
| ES (1) | ES2224726T3 (https=) |
| HK (1) | HK1041454B (https=) |
| PT (1) | PT1144026E (https=) |
| WO (1) | WO2000038762A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018100756A (ja) * | 2016-12-21 | 2018-06-28 | 三井電気精機株式会社 | 遠心分離システム |
| JP2018100771A (ja) * | 2017-12-12 | 2018-06-28 | 三井電気精機株式会社 | 回転体駆動・シール構造及びこれを含む遠心分離装置 |
Families Citing this family (174)
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| DE10134913C2 (de) | 2001-07-18 | 2003-06-26 | Hiberna Ag | Vorrichtung und Verfahren zur Blutpräparation |
| WO2003050536A2 (en) * | 2001-12-05 | 2003-06-19 | Gambro, Inc. | Methods and apparatus for separation of blood components |
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| EP2399990B1 (en) | 2003-06-27 | 2015-07-22 | DePuy Synthes Products, Inc. | Cells derived from post-partum umbilical cord for use in treatment of disease of the heart and circulatory system |
| US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
| US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
| ITMI20031715A1 (it) | 2003-09-05 | 2005-03-06 | Dideco Spa | Dispositivo di comando nella raccolta differenziata dei |
| US7060018B2 (en) | 2003-09-11 | 2006-06-13 | Cobe Cardiovascular, Inc. | Centrifuge apparatus for processing blood |
| EP1671664B1 (en) * | 2003-10-02 | 2017-05-03 | Terumo Kabushiki Kaisha | Method of producing blood processing circuits and filter unit |
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| WO2007070870A1 (en) | 2005-12-16 | 2007-06-21 | Ethicon, Inc. | Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
| PL2471907T3 (pl) | 2005-12-29 | 2019-07-31 | Celularity, Inc. | Populacje komórek macierzystych łożyska |
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| RU2536242C2 (ru) | 2007-09-28 | 2014-12-20 | Антродженезис Корпорейшн | Угнетение опухолей с помощью плацентарного перфузата человека и выделенных из плаценты человека вспомогательных натуральных клеток-киллеров |
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- 1999-12-24 CN CNB998150223A patent/CN1182882C/zh not_active Expired - Lifetime
- 1999-12-24 DE DE69919029T patent/DE69919029T2/de not_active Expired - Lifetime
- 1999-12-24 AU AU16756/00A patent/AU1675600A/en not_active Abandoned
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| CN109477581A (zh) * | 2016-12-21 | 2019-03-15 | 三井电气精机株式会社 | 旋转体驱动/密封结构以及包括该旋转体驱动/密封结构的离心分离装置和离心分离系统 |
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| JP2018100771A (ja) * | 2017-12-12 | 2018-06-28 | 三井電気精機株式会社 | 回転体駆動・シール構造及びこれを含む遠心分離装置 |
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| AU1675600A (en) | 2000-07-31 |
| CN1331610A (zh) | 2002-01-16 |
| WO2000038762A1 (en) | 2000-07-06 |
| JP2002533171A (ja) | 2002-10-08 |
| ATE271890T1 (de) | 2004-08-15 |
| EP1144026A1 (en) | 2001-10-17 |
| EP1144026B1 (en) | 2004-07-28 |
| DE69919029T2 (de) | 2005-09-08 |
| ES2224726T3 (es) | 2005-03-01 |
| US6733433B1 (en) | 2004-05-11 |
| HK1041454B (en) | 2004-12-31 |
| CN1182882C (zh) | 2005-01-05 |
| PT1144026E (pt) | 2004-12-31 |
| HK1041454A1 (en) | 2002-07-12 |
| DE69919029D1 (de) | 2004-09-02 |
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