JP4451060B2 - 多剤耐性を治療するための置換複素環式化合物 - Google Patents

多剤耐性を治療するための置換複素環式化合物 Download PDF

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JP4451060B2
JP4451060B2 JP2002536053A JP2002536053A JP4451060B2 JP 4451060 B2 JP4451060 B2 JP 4451060B2 JP 2002536053 A JP2002536053 A JP 2002536053A JP 2002536053 A JP2002536053 A JP 2002536053A JP 4451060 B2 JP4451060 B2 JP 4451060B2
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mmol
room temperature
piperidine
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phenyl
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JP2004511546A (ja
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レイモンド デゲンハルト チャールズ
ジョセフ エイコフ デイビッド
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エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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JP2002536053A 2000-10-17 2001-10-16 多剤耐性を治療するための置換複素環式化合物 Expired - Fee Related JP4451060B2 (ja)

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US24112700P 2000-10-17 2000-10-17
US09/740,643 US6376514B1 (en) 2000-10-17 2000-12-19 Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
PCT/US2001/042781 WO2002032869A2 (en) 2000-10-17 2001-10-16 Substituted heterocyclic compounds for treating multidrug resistance

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US7135483B2 (en) 2006-11-14
US7476680B2 (en) 2009-01-13
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EP1326833B1 (en) 2010-06-02
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US6376514B1 (en) 2002-04-23
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