JP4402833B2 - リポペプチド抗生物質カルシウム塩、その製造方法およびその使用 - Google Patents

リポペプチド抗生物質カルシウム塩、その製造方法およびその使用 Download PDF

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Publication number
JP4402833B2
JP4402833B2 JP2000533451A JP2000533451A JP4402833B2 JP 4402833 B2 JP4402833 B2 JP 4402833B2 JP 2000533451 A JP2000533451 A JP 2000533451A JP 2000533451 A JP2000533451 A JP 2000533451A JP 4402833 B2 JP4402833 B2 JP 4402833B2
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Japan
Prior art keywords
formula
salt
calcium salt
anion
integer
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Expired - Fee Related
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JP2000533451A
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English (en)
Japanese (ja)
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JP2002528382A5 (https=
JP2002528382A (ja
Inventor
ラースロウ・フェルテシ
ヴェルナー・アーレツ
ハインリヒ・デッカー
エーバーハルト・エーラース
ミヒャエル・クルツ
フランク・ライナー・シュミット
Original Assignee
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2000533451A 1998-02-25 1999-02-12 リポペプチド抗生物質カルシウム塩、その製造方法およびその使用 Expired - Fee Related JP4402833B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19807972A DE19807972A1 (de) 1998-02-25 1998-02-25 Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
DE19807972.9 1998-02-25
PCT/EP1999/000930 WO1999043700A1 (de) 1998-02-25 1999-02-12 Lipopeptidantibiotika-calciumsalze, verfahren zu ihrer herstellung und verwendung

Publications (3)

Publication Number Publication Date
JP2002528382A JP2002528382A (ja) 2002-09-03
JP2002528382A5 JP2002528382A5 (https=) 2006-03-30
JP4402833B2 true JP4402833B2 (ja) 2010-01-20

Family

ID=7858906

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000533451A Expired - Fee Related JP4402833B2 (ja) 1998-02-25 1999-02-12 リポペプチド抗生物質カルシウム塩、その製造方法およびその使用

Country Status (15)

Country Link
US (1) US6624143B1 (https=)
EP (1) EP1068223B1 (https=)
JP (1) JP4402833B2 (https=)
AR (1) AR016713A1 (https=)
AT (1) ATE223433T1 (https=)
AU (1) AU2725299A (https=)
CA (1) CA2322052C (https=)
CO (1) CO4790157A1 (https=)
DE (2) DE19807972A1 (https=)
DK (1) DK1068223T3 (https=)
ES (1) ES2182489T3 (https=)
PT (1) PT1068223E (https=)
TW (1) TW559623B (https=)
WO (1) WO1999043700A1 (https=)
ZA (1) ZA991482B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2394313A1 (en) 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Novel lipopeptides as antibacterial agents
MXPA02006029A (es) 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
AU784812B2 (en) 1999-12-15 2006-06-29 Merck Sharp & Dohme Corp. Lipopeptides as antibacterial agents
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
NZ554405A (en) † 2000-12-18 2009-04-30 Cubist Pharm Inc Method for preparing crystalline and crystal-like forms of purified lipopeptides
US7125844B2 (en) 2002-01-03 2006-10-24 Migenix Inc. Dab9 derivatives of lipopeptide antibiotics and methods of making and using the same
AU2004252174A1 (en) 2003-06-26 2005-01-06 Migenix Inc. Compositions of lipopeptide antibiotic derivatives and methods of use thereof
US7795207B2 (en) 2005-11-21 2010-09-14 Harald Labischinski Lipopeptide compositions
DE102005056194A1 (de) * 2005-11-21 2007-07-12 Combinature Biopharm Ag Neue Lipopeptid Zusammensetzungen
GB0821540D0 (en) 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
PL2379580T3 (pl) * 2008-12-22 2014-05-30 Merck Sharp & Dohme Nowe środki przeciwbakteryjne do leczenia zakażeń wywołanych bakteriami Gram-dodatnimi
SG10201407724YA (en) 2009-11-23 2014-12-30 Cubist Pharm Inc Daptomycin compositions and related methods
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
CN109476704B (zh) * 2016-04-08 2022-08-16 港大科桥有限公司 抗菌环脂肽

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
GB8720980D0 (en) * 1987-09-07 1987-10-14 Lepetit Spa Derivatives
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US6309440B1 (en) * 1998-08-25 2001-10-30 Thomas T. Yamashita Method and composition for promoting and controlling growth of plants
TW455591B (en) * 1993-06-08 2001-09-21 Hoechst Ag Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US6291680B1 (en) * 1997-06-18 2001-09-18 Fujisawa Pharmaceutical Co., Ltd. Production process

Also Published As

Publication number Publication date
TW559623B (en) 2003-11-01
JP2002528382A (ja) 2002-09-03
US6624143B1 (en) 2003-09-23
AU2725299A (en) 1999-09-15
ATE223433T1 (de) 2002-09-15
DE59902568D1 (de) 2002-10-10
CA2322052C (en) 2009-09-29
EP1068223B1 (de) 2002-09-04
CO4790157A1 (es) 1999-05-31
CA2322052A1 (en) 1999-09-02
AR016713A1 (es) 2001-07-25
WO1999043700A1 (de) 1999-09-02
DK1068223T3 (da) 2002-12-30
ZA991482B (en) 1999-08-25
EP1068223A1 (de) 2001-01-17
PT1068223E (pt) 2003-01-31
DE19807972A1 (de) 1999-08-26
ES2182489T3 (es) 2003-03-01

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