TW559623B - Lipopeptide antibiotic calcium salts, process for their preparation, and their use - Google Patents

Lipopeptide antibiotic calcium salts, process for their preparation, and their use Download PDF

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Publication number
TW559623B
TW559623B TW088102584A TW88102584A TW559623B TW 559623 B TW559623 B TW 559623B TW 088102584 A TW088102584 A TW 088102584A TW 88102584 A TW88102584 A TW 88102584A TW 559623 B TW559623 B TW 559623B
Authority
TW
Taiwan
Prior art keywords
patent application
scope
calcium salt
item
salt
Prior art date
Application number
TW088102584A
Other languages
English (en)
Chinese (zh)
Inventor
Laszlo Vertesy
Werner Aretz
Heinrich Decker
Eberhard Ehlers
Michael Kurz
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of TW559623B publication Critical patent/TW559623B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW088102584A 1998-02-25 1999-02-23 Lipopeptide antibiotic calcium salts, process for their preparation, and their use TW559623B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19807972A DE19807972A1 (de) 1998-02-25 1998-02-25 Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
TW559623B true TW559623B (en) 2003-11-01

Family

ID=7858906

Family Applications (1)

Application Number Title Priority Date Filing Date
TW088102584A TW559623B (en) 1998-02-25 1999-02-23 Lipopeptide antibiotic calcium salts, process for their preparation, and their use

Country Status (15)

Country Link
US (1) US6624143B1 (https=)
EP (1) EP1068223B1 (https=)
JP (1) JP4402833B2 (https=)
AR (1) AR016713A1 (https=)
AT (1) ATE223433T1 (https=)
AU (1) AU2725299A (https=)
CA (1) CA2322052C (https=)
CO (1) CO4790157A1 (https=)
DE (2) DE19807972A1 (https=)
DK (1) DK1068223T3 (https=)
ES (1) ES2182489T3 (https=)
PT (1) PT1068223E (https=)
TW (1) TW559623B (https=)
WO (1) WO1999043700A1 (https=)
ZA (1) ZA991482B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1425025A (zh) 1999-12-15 2003-06-18 卡比斯特制药公司 作为抗菌剂的新颖的脂肽
WO2001044274A1 (en) 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
MXPA02006028A (es) 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
IL156394A0 (en) † 2000-12-18 2004-01-04 Cubist Pharm Inc Methods for preparing purified lipopeptides
JP4402463B2 (ja) 2002-01-03 2010-01-20 マイジェニックス インコーポレイテッド リポペプチド抗生物質のＤａｂ９誘導体およびそれを製造および使用する方法
CN1839150A (zh) 2003-07-17 2006-09-27 麦根克斯有限公司 脂肽抗菌衍生物组合物及其应用方法
DE102005056194A1 (de) * 2005-11-21 2007-07-12 Combinature Biopharm Ag Neue Lipopeptid Zusammensetzungen
US7795207B2 (en) 2005-11-21 2010-09-14 Harald Labischinski Lipopeptide compositions
GB0821540D0 (en) 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
BRPI0923567A2 (pt) 2008-12-22 2016-09-27 Cubist Pharm Inc agentes antibactericidas novos para o tratamento de infecções gram positivas
RU2607526C2 (ru) 2009-11-23 2017-01-10 Кьюбист Фармасьютикалз ЭлЭлСи Липопептидные композиции и родственные способы
US11667674B2 (en) 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
CN109476704B (zh) * 2016-04-08 2022-08-16 港大科桥有限公司 抗菌环脂肽

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
GB8720980D0 (en) * 1987-09-07 1987-10-14 Lepetit Spa Derivatives
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US6309440B1 (en) * 1998-08-25 2001-10-30 Thomas T. Yamashita Method and composition for promoting and controlling growth of plants
TW455591B (en) 1993-06-08 2001-09-21 Hoechst Ag Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0994101A4 (en) * 1997-06-18 2002-05-02 Fujisawa Pharmaceutical Co NEW PREPARATION PROCESS

Also Published As

Publication number Publication date
PT1068223E (pt) 2003-01-31
JP4402833B2 (ja) 2010-01-20
ZA991482B (en) 1999-08-25
AR016713A1 (es) 2001-07-25
EP1068223A1 (de) 2001-01-17
EP1068223B1 (de) 2002-09-04
DK1068223T3 (da) 2002-12-30
US6624143B1 (en) 2003-09-23
ATE223433T1 (de) 2002-09-15
CO4790157A1 (es) 1999-05-31
JP2002528382A (ja) 2002-09-03
CA2322052A1 (en) 1999-09-02
ES2182489T3 (es) 2003-03-01
DE19807972A1 (de) 1999-08-26
CA2322052C (en) 2009-09-29
AU2725299A (en) 1999-09-15
DE59902568D1 (de) 2002-10-10
WO1999043700A1 (de) 1999-09-02

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