TW559623B - Lipopeptide antibiotic calcium salts, process for their preparation, and their use - Google Patents

Lipopeptide antibiotic calcium salts, process for their preparation, and their use Download PDF

Info

Publication number
TW559623B
TW559623B TW088102584A TW88102584A TW559623B TW 559623 B TW559623 B TW 559623B TW 088102584 A TW088102584 A TW 088102584A TW 88102584 A TW88102584 A TW 88102584A TW 559623 B TW559623 B TW 559623B
Authority
TW
Taiwan
Prior art keywords
patent application
scope
calcium salt
item
salt
Prior art date
Application number
TW088102584A
Other languages
English (en)
Chinese (zh)
Inventor
Laszlo Vertesy
Werner Aretz
Heinrich Decker
Eberhard Ehlers
Michael Kurz
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of TW559623B publication Critical patent/TW559623B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045Actinoplanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW088102584A 1998-02-25 1999-02-23 Lipopeptide antibiotic calcium salts, process for their preparation, and their use TW559623B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19807972A DE19807972A1 (de) 1998-02-25 1998-02-25 Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
TW559623B true TW559623B (en) 2003-11-01

Family

ID=7858906

Family Applications (1)

Application Number Title Priority Date Filing Date
TW088102584A TW559623B (en) 1998-02-25 1999-02-23 Lipopeptide antibiotic calcium salts, process for their preparation, and their use

Country Status (15)

Country Link
US (1) US6624143B1 (https=)
EP (1) EP1068223B1 (https=)
JP (1) JP4402833B2 (https=)
AR (1) AR016713A1 (https=)
AT (1) ATE223433T1 (https=)
AU (1) AU2725299A (https=)
CA (1) CA2322052C (https=)
CO (1) CO4790157A1 (https=)
DE (2) DE19807972A1 (https=)
DK (1) DK1068223T3 (https=)
ES (1) ES2182489T3 (https=)
PT (1) PT1068223E (https=)
TW (1) TW559623B (https=)
WO (1) WO1999043700A1 (https=)
ZA (1) ZA991482B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2394313A1 (en) 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Novel lipopeptides as antibacterial agents
MXPA02006029A (es) 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
AU784812B2 (en) 1999-12-15 2006-06-29 Merck Sharp & Dohme Corp. Lipopeptides as antibacterial agents
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
NZ554405A (en) 2000-12-18 2009-04-30 Cubist Pharm Inc Method for preparing crystalline and crystal-like forms of purified lipopeptides
US7125844B2 (en) 2002-01-03 2006-10-24 Migenix Inc. Dab9 derivatives of lipopeptide antibiotics and methods of making and using the same
AU2004252174A1 (en) 2003-06-26 2005-01-06 Migenix Inc. Compositions of lipopeptide antibiotic derivatives and methods of use thereof
US7795207B2 (en) 2005-11-21 2010-09-14 Harald Labischinski Lipopeptide compositions
DE102005056194A1 (de) * 2005-11-21 2007-07-12 Combinature Biopharm Ag Neue Lipopeptid Zusammensetzungen
GB0821540D0 (en) 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
PL2379580T3 (pl) * 2008-12-22 2014-05-30 Merck Sharp & Dohme Nowe środki przeciwbakteryjne do leczenia zakażeń wywołanych bakteriami Gram-dodatnimi
SG10201407724YA (en) 2009-11-23 2014-12-30 Cubist Pharm Inc Daptomycin compositions and related methods
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
CN109476704B (zh) * 2016-04-08 2022-08-16 港大科桥有限公司 抗菌环脂肽

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
GB8720980D0 (en) * 1987-09-07 1987-10-14 Lepetit Spa Derivatives
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US6309440B1 (en) * 1998-08-25 2001-10-30 Thomas T. Yamashita Method and composition for promoting and controlling growth of plants
TW455591B (en) * 1993-06-08 2001-09-21 Hoechst Ag Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US6291680B1 (en) * 1997-06-18 2001-09-18 Fujisawa Pharmaceutical Co., Ltd. Production process

Also Published As

Publication number Publication date
JP2002528382A (ja) 2002-09-03
US6624143B1 (en) 2003-09-23
AU2725299A (en) 1999-09-15
ATE223433T1 (de) 2002-09-15
DE59902568D1 (de) 2002-10-10
CA2322052C (en) 2009-09-29
EP1068223B1 (de) 2002-09-04
CO4790157A1 (es) 1999-05-31
CA2322052A1 (en) 1999-09-02
AR016713A1 (es) 2001-07-25
WO1999043700A1 (de) 1999-09-02
DK1068223T3 (da) 2002-12-30
ZA991482B (en) 1999-08-25
EP1068223A1 (de) 2001-01-17
PT1068223E (pt) 2003-01-31
DE19807972A1 (de) 1999-08-26
JP4402833B2 (ja) 2010-01-20
ES2182489T3 (es) 2003-03-01

Similar Documents

Publication Publication Date Title
TW559623B (en) Lipopeptide antibiotic calcium salts, process for their preparation, and their use
CN1982330B (zh) 制备纯化脂肽的方法
US6057291A (en) Antimicrobial cationic peptides
KR20170078830A (ko) 글리코펩티드 조성물
PT1586580E (pt) Processo para a purificação de daptomicina
AU2002246687A1 (en) Methods for preparing purified lipopeptides
WO1996038473A2 (en) Antimicrobial cationic peptides
CN116874614B (zh) 一种具有高活性低裂解效果的抗菌多肽aph171及其制备方法和应用
JP2019014905A (ja) 優れた広域スペクトル抗微生物活性および高い選択性を有するカチオン性ペプチド多糖類
CN105924456B (zh) 一种减少不良反应的头孢米诺钠化合物及其制剂
CN110612306B (zh) 新缩肽类及其用途
AU763351B2 (en) Reversible boronate complexes of 1,2-(cis)-diol cyclic-peptides
JPH05271096A (ja) 抗菌性組成物及びそれを有効成分とする薬剤
CN102558307B (zh) 一种八肽菌素及其制备与应用
CN118005741B (zh) 一种抗菌多肽ap16a及其制备方法和应用
CN106661090A (zh) 低取代的多粘菌素以及它们的组合物
WO2012161951A1 (en) Peptides for preventing or treating a disease or disorder associated with cbp or p300 misregulation, and methods for use and identification thereof
JP4729047B2 (ja) 純粋なバンコマイシン塩酸塩
JP2025525741A (ja) リポオリゴ尿素、医薬組成物、及び薬剤としての使用のためのリポオリゴ尿素
DK171235B1 (da) Krystallinsk (5R,6S)-2-carbamoyloxymethyl-6-[(IR)-hydroxyethyl]-2-penemcarboxylsyre, fremgangsmåde til fremstilling heraf, samt farmaceutisk præparat indeholdende syren
CN118878628B (zh) 一种稳定的自组装抗菌肽rw7及其制备方法和应用
CN121086024A (zh) 抑制耐药性革兰氏阴性菌和革兰氏阳性菌的新型抗菌肽及其制备方法
CN118005739A (zh) 一种抗耐药菌株的多肽aph229及其制备方法和应用
CN121574193A (zh) 基于fk3的碳硼烷偶联肽及其制备方法和应用
WO2012154109A1 (en) Self -aggregating antimicrobial cyclic peptides comprising beta - tri substituted amino acid residues

Legal Events

Date Code Title Description
GD4A Issue of patent certificate for granted invention patent
MM4A Annulment or lapse of patent due to non-payment of fees