ATE223433T1 - Lipopeptidantibiotika-calciumsalze, verfahren zu ihrer herstellung und verwendung - Google Patents

Lipopeptidantibiotika-calciumsalze, verfahren zu ihrer herstellung und verwendung

Info

Publication number
ATE223433T1
ATE223433T1 AT99907547T AT99907547T ATE223433T1 AT E223433 T1 ATE223433 T1 AT E223433T1 AT 99907547 T AT99907547 T AT 99907547T AT 99907547 T AT99907547 T AT 99907547T AT E223433 T1 ATE223433 T1 AT E223433T1
Authority
AT
Austria
Prior art keywords
preparation
calcium salts
lipopeptide antibiotic
antibiotic calcium
lipopeptide
Prior art date
Application number
AT99907547T
Other languages
German (de)
English (en)
Inventor
Laszlo Vertesy
Werner Aretz
Heinrich Decker
Eberhard Ehlers
Michael Kurz
Frank Rainer Schmidt
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of ATE223433T1 publication Critical patent/ATE223433T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045Actinoplanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99907547T 1998-02-25 1999-02-12 Lipopeptidantibiotika-calciumsalze, verfahren zu ihrer herstellung und verwendung ATE223433T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19807972A DE19807972A1 (de) 1998-02-25 1998-02-25 Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
PCT/EP1999/000930 WO1999043700A1 (de) 1998-02-25 1999-02-12 Lipopeptidantibiotika-calciumsalze, verfahren zu ihrer herstellung und verwendung

Publications (1)

Publication Number Publication Date
ATE223433T1 true ATE223433T1 (de) 2002-09-15

Family

ID=7858906

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99907547T ATE223433T1 (de) 1998-02-25 1999-02-12 Lipopeptidantibiotika-calciumsalze, verfahren zu ihrer herstellung und verwendung

Country Status (15)

Country Link
US (1) US6624143B1 (https=)
EP (1) EP1068223B1 (https=)
JP (1) JP4402833B2 (https=)
AR (1) AR016713A1 (https=)
AT (1) ATE223433T1 (https=)
AU (1) AU2725299A (https=)
CA (1) CA2322052C (https=)
CO (1) CO4790157A1 (https=)
DE (2) DE19807972A1 (https=)
DK (1) DK1068223T3 (https=)
ES (1) ES2182489T3 (https=)
PT (1) PT1068223E (https=)
TW (1) TW559623B (https=)
WO (1) WO1999043700A1 (https=)
ZA (1) ZA991482B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1425025A (zh) 1999-12-15 2003-06-18 卡比斯特制药公司 作为抗菌剂的新颖的脂肽
WO2001044274A1 (en) 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
MXPA02006028A (es) 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
IL156394A0 (en) 2000-12-18 2004-01-04 Cubist Pharm Inc Methods for preparing purified lipopeptides
JP4402463B2 (ja) 2002-01-03 2010-01-20 マイジェニックス インコーポレイテッド リポペプチド抗生物質のDab9誘導体およびそれを製造および使用する方法
CN1839150A (zh) 2003-07-17 2006-09-27 麦根克斯有限公司 脂肽抗菌衍生物组合物及其应用方法
DE102005056194A1 (de) * 2005-11-21 2007-07-12 Combinature Biopharm Ag Neue Lipopeptid Zusammensetzungen
US7795207B2 (en) 2005-11-21 2010-09-14 Harald Labischinski Lipopeptide compositions
GB0821540D0 (en) 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
BRPI0923567A2 (pt) 2008-12-22 2016-09-27 Cubist Pharm Inc agentes antibactericidas novos para o tratamento de infecções gram positivas
RU2607526C2 (ru) 2009-11-23 2017-01-10 Кьюбист Фармасьютикалз ЭлЭлСи Липопептидные композиции и родственные способы
US11667674B2 (en) 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
CN109476704B (zh) * 2016-04-08 2022-08-16 港大科桥有限公司 抗菌环脂肽

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
GB8720980D0 (en) * 1987-09-07 1987-10-14 Lepetit Spa Derivatives
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US6309440B1 (en) * 1998-08-25 2001-10-30 Thomas T. Yamashita Method and composition for promoting and controlling growth of plants
TW455591B (en) 1993-06-08 2001-09-21 Hoechst Ag Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0994101A4 (en) * 1997-06-18 2002-05-02 Fujisawa Pharmaceutical Co NEW PREPARATION PROCESS

Also Published As

Publication number Publication date
PT1068223E (pt) 2003-01-31
JP4402833B2 (ja) 2010-01-20
ZA991482B (en) 1999-08-25
AR016713A1 (es) 2001-07-25
EP1068223A1 (de) 2001-01-17
EP1068223B1 (de) 2002-09-04
DK1068223T3 (da) 2002-12-30
US6624143B1 (en) 2003-09-23
TW559623B (en) 2003-11-01
CO4790157A1 (es) 1999-05-31
JP2002528382A (ja) 2002-09-03
CA2322052A1 (en) 1999-09-02
ES2182489T3 (es) 2003-03-01
DE19807972A1 (de) 1999-08-26
CA2322052C (en) 2009-09-29
AU2725299A (en) 1999-09-15
DE59902568D1 (de) 2002-10-10
WO1999043700A1 (de) 1999-09-02

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