DK1068223T3 - Lipopeptidantibiotika-calciumsalte, fremgangsmåde til deres fremstilling og anvendelse - Google Patents

Lipopeptidantibiotika-calciumsalte, fremgangsmåde til deres fremstilling og anvendelse

Info

Publication number
DK1068223T3
DK1068223T3 DK99907547T DK99907547T DK1068223T3 DK 1068223 T3 DK1068223 T3 DK 1068223T3 DK 99907547 T DK99907547 T DK 99907547T DK 99907547 T DK99907547 T DK 99907547T DK 1068223 T3 DK1068223 T3 DK 1068223T3
Authority
DK
Denmark
Prior art keywords
preparation
calcium salts
lipopeptide antibiotic
antibiotic calcium
lipopeptide
Prior art date
Application number
DK99907547T
Other languages
English (en)
Inventor
Werner Aretz
Heinrich Decker
Eberhard Ehlers
Michael Kurz
Frank Rainer Schmidt
Laszlo Vertesy
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of DK1068223T3 publication Critical patent/DK1068223T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045Actinoplanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99907547T 1998-02-25 1999-02-12 Lipopeptidantibiotika-calciumsalte, fremgangsmåde til deres fremstilling og anvendelse DK1068223T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19807972A DE19807972A1 (de) 1998-02-25 1998-02-25 Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
PCT/EP1999/000930 WO1999043700A1 (de) 1998-02-25 1999-02-12 Lipopeptidantibiotika-calciumsalze, verfahren zu ihrer herstellung und verwendung

Publications (1)

Publication Number Publication Date
DK1068223T3 true DK1068223T3 (da) 2002-12-30

Family

ID=7858906

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99907547T DK1068223T3 (da) 1998-02-25 1999-02-12 Lipopeptidantibiotika-calciumsalte, fremgangsmåde til deres fremstilling og anvendelse

Country Status (15)

Country Link
US (1) US6624143B1 (da)
EP (1) EP1068223B1 (da)
JP (1) JP4402833B2 (da)
AR (1) AR016713A1 (da)
AT (1) ATE223433T1 (da)
AU (1) AU2725299A (da)
CA (1) CA2322052C (da)
CO (1) CO4790157A1 (da)
DE (2) DE19807972A1 (da)
DK (1) DK1068223T3 (da)
ES (1) ES2182489T3 (da)
PT (1) PT1068223E (da)
TW (1) TW559623B (da)
WO (1) WO1999043700A1 (da)
ZA (1) ZA991482B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA02006030A (es) 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos como agentes antibacterianos.
US6794490B2 (en) 1999-12-15 2004-09-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
AU784755B2 (en) 1999-12-15 2006-06-08 Merck Sharp & Dohme Corp. Daptomycin Analogs as antibacterial agents
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
CN1592753A (zh) * 2000-12-18 2005-03-09 卡比斯特制药公司 制备纯化脂肽的方法
AU2003202878B2 (en) 2002-01-03 2008-07-31 Migenix Inc. Dab9 derivatives of lipopeptide antibiotics and methods of making and using the same
JP2007536200A (ja) 2003-07-17 2007-12-13 ミジェニックス インコーポレイテッド リポペプチド抗生物質誘導体の組成物およびその使用方法
DE102005056194A1 (de) * 2005-11-21 2007-07-12 Combinature Biopharm Ag Neue Lipopeptid Zusammensetzungen
US7795207B2 (en) 2005-11-21 2010-09-14 Harald Labischinski Lipopeptide compositions
GB0821540D0 (en) * 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
RU2512396C2 (ru) 2008-12-22 2014-04-10 Кьюбист Фармасьютикалз, Инк. Новые противобактериальные средства для лечения грамположительных инфекций
PE20151717A1 (es) 2009-11-23 2015-11-19 Cubist Pharm Inc Compuestos lipopeptidos y metodos relacionados
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
WO2017173932A1 (en) * 2016-04-08 2017-10-12 Versitech Limited Antibacterial cyclic lipopeptides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
GB8720980D0 (en) * 1987-09-07 1987-10-14 Lepetit Spa Derivatives
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US6309440B1 (en) * 1998-08-25 2001-10-30 Thomas T. Yamashita Method and composition for promoting and controlling growth of plants
TW455591B (en) * 1993-06-08 2001-09-21 Hoechst Ag Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
DE4411025A1 (de) * 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0994101A4 (en) * 1997-06-18 2002-05-02 Fujisawa Pharmaceutical Co NEW PREPARATION PROCESS

Also Published As

Publication number Publication date
PT1068223E (pt) 2003-01-31
AU2725299A (en) 1999-09-15
CA2322052C (en) 2009-09-29
EP1068223A1 (de) 2001-01-17
ATE223433T1 (de) 2002-09-15
TW559623B (en) 2003-11-01
EP1068223B1 (de) 2002-09-04
AR016713A1 (es) 2001-07-25
US6624143B1 (en) 2003-09-23
CO4790157A1 (es) 1999-05-31
JP2002528382A (ja) 2002-09-03
JP4402833B2 (ja) 2010-01-20
ES2182489T3 (es) 2003-03-01
DE59902568D1 (de) 2002-10-10
DE19807972A1 (de) 1999-08-26
ZA991482B (en) 1999-08-25
WO1999043700A1 (de) 1999-09-02
CA2322052A1 (en) 1999-09-02

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