JP4304309B2 - 毒物学および投薬予測のための動物モデル - Google Patents

毒物学および投薬予測のための動物モデル Download PDF

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Publication number
JP4304309B2
JP4304309B2 JP2004508558A JP2004508558A JP4304309B2 JP 4304309 B2 JP4304309 B2 JP 4304309B2 JP 2004508558 A JP2004508558 A JP 2004508558A JP 2004508558 A JP2004508558 A JP 2004508558A JP 4304309 B2 JP4304309 B2 JP 4304309B2
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tissue
human
target
animal
cells
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Japanese (ja)
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JP2005527226A5 (https=
JP2005527226A (ja
Inventor
ジェニー ピー. マーサー,
ピーター エフ. ヤング,
Original Assignee
レイベン バイオテクノロジーズ,インコーポレイティド
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0271Chimeric vertebrates, e.g. comprising exogenous cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/30Bird
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2004508558A 2002-05-30 2003-05-30 毒物学および投薬予測のための動物モデル Expired - Fee Related JP4304309B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38471502P 2002-05-30 2002-05-30
PCT/US2003/017285 WO2003101187A1 (en) 2002-05-30 2003-05-30 Animal model for toxicology and dose prediction

Publications (3)

Publication Number Publication Date
JP2005527226A JP2005527226A (ja) 2005-09-15
JP2005527226A5 JP2005527226A5 (https=) 2006-03-16
JP4304309B2 true JP4304309B2 (ja) 2009-07-29

Family

ID=29712081

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004508558A Expired - Fee Related JP4304309B2 (ja) 2002-05-30 2003-05-30 毒物学および投薬予測のための動物モデル

Country Status (11)

Country Link
US (2) US20040045045A1 (https=)
EP (1) EP1507454A4 (https=)
JP (1) JP4304309B2 (https=)
KR (1) KR20050004263A (https=)
CN (1) CN1655671A (https=)
AU (1) AU2003249675B2 (https=)
CA (1) CA2486548A1 (https=)
IL (2) IL165128A (https=)
MX (1) MXPA04011828A (https=)
NZ (1) NZ536553A (https=)
WO (1) WO2003101187A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7148038B2 (en) * 2001-10-16 2006-12-12 Raven Biotechnologies, Inc. Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof
GB0427916D0 (en) * 2004-12-21 2005-01-19 Astrazeneca Ab Method
RU2325641C1 (ru) * 2006-11-20 2008-05-27 Наталья Александровна Уракова Способ экспресс-оценки степени безопасности лекарственных средств для инъекций
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
EP3332814B1 (en) * 2015-08-03 2024-11-06 FUJIFILM Corporation Cell structure, rodent model animal, method for producing rodent model animal, and method for evaluating test substance
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
KR101920048B1 (ko) * 2016-10-17 2018-11-19 건국대학교 산학협력단 피부 독성 평가용 지렁이 동물모델 및 이를 이용한 인간 피부 독성 평가방법
JP7478720B2 (ja) * 2018-04-13 2024-05-07 シャンハイ エルアイディーイー バイオテック カンパニー リミテッド 条件付き再プログラム化細胞から動物モデルを得るための方法および抗腫瘍薬のスクリーニングのための動物モデルの使用
CN114711192B (zh) * 2022-04-13 2022-11-29 中国科学院西北高原生物研究所 一种长效抑郁症动物模型的构建试剂盒及构建方法
CN117016488B (zh) * 2023-08-16 2025-09-16 中国水产科学研究院淡水渔业研究中心 一种大口黑鲈xy型遗传雄鱼性反转为xy型伪雌鱼的诱导剂及诱导方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476996A (en) * 1988-06-14 1995-12-19 Lidak Pharmaceuticals Human immune system in non-human animal
KR950701230A (ko) * 1993-03-04 1995-03-23 죤제이 쉬바르츠 작은 동물 전이모델(small animal metastasis model)
US5698413A (en) * 1993-05-05 1997-12-16 The United States Of America As Represented By The Department Of Health And Human Services Method of evaluating chemotherapeutic agents in vivo
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
US6436704B1 (en) * 2000-04-10 2002-08-20 Raven Biotechnologies, Inc. Human pancreatic epithelial progenitor cells and methods of isolation and use thereof

Also Published As

Publication number Publication date
AU2003249675A1 (en) 2003-12-19
CN1655671A (zh) 2005-08-17
JP2005527226A (ja) 2005-09-15
WO2003101187A1 (en) 2003-12-11
EP1507454A4 (en) 2007-11-21
US20040045045A1 (en) 2004-03-04
US20120110682A1 (en) 2012-05-03
NZ536553A (en) 2008-10-31
EP1507454A1 (en) 2005-02-23
IL165128A (en) 2010-12-30
MXPA04011828A (es) 2005-11-23
CA2486548A1 (en) 2003-12-11
IL207587A (en) 2011-08-31
IL165128A0 (en) 2005-12-18
KR20050004263A (ko) 2005-01-12
AU2003249675B2 (en) 2008-06-05

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