JP2005527226A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005527226A5 JP2005527226A5 JP2004508558A JP2004508558A JP2005527226A5 JP 2005527226 A5 JP2005527226 A5 JP 2005527226A5 JP 2004508558 A JP2004508558 A JP 2004508558A JP 2004508558 A JP2004508558 A JP 2004508558A JP 2005527226 A5 JP2005527226 A5 JP 2005527226A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- target
- human
- animal
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001519 tissue Anatomy 0.000 claims 42
- 238000000034 method Methods 0.000 claims 23
- 241000282414 Homo sapiens Species 0.000 claims 21
- 241001465754 Metazoa Species 0.000 claims 21
- 201000010099 disease Diseases 0.000 claims 17
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 17
- 206010028980 Neoplasm Diseases 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 11
- 238000011282 treatment Methods 0.000 claims 11
- 201000011510 cancer Diseases 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 8
- 229940079593 drug Drugs 0.000 claims 8
- 241000251539 Vertebrata <Metazoa> Species 0.000 claims 7
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 5
- 241000894007 species Species 0.000 claims 5
- 238000012360 testing method Methods 0.000 claims 4
- 230000001225 therapeutic effect Effects 0.000 claims 4
- 231100000331 toxic Toxicity 0.000 claims 4
- 230000002588 toxic effect Effects 0.000 claims 4
- 241000283984 Rodentia Species 0.000 claims 3
- 210000002216 heart Anatomy 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 230000001817 pituitary effect Effects 0.000 claims 3
- 210000003491 skin Anatomy 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 241000282472 Canis lupus familiaris Species 0.000 claims 2
- 241000283707 Capra Species 0.000 claims 2
- 241000282326 Felis catus Species 0.000 claims 2
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 2
- 241001494479 Pecora Species 0.000 claims 2
- 241000700159 Rattus Species 0.000 claims 2
- 210000000038 chest Anatomy 0.000 claims 2
- 210000001072 colon Anatomy 0.000 claims 2
- 238000011161 development Methods 0.000 claims 2
- 210000001198 duodenum Anatomy 0.000 claims 2
- 210000003743 erythrocyte Anatomy 0.000 claims 2
- 210000003734 kidney Anatomy 0.000 claims 2
- 210000004185 liver Anatomy 0.000 claims 2
- 210000004072 lung Anatomy 0.000 claims 2
- 210000004698 lymphocyte Anatomy 0.000 claims 2
- 210000001616 monocyte Anatomy 0.000 claims 2
- 210000002307 prostate Anatomy 0.000 claims 2
- 210000003079 salivary gland Anatomy 0.000 claims 2
- 210000000952 spleen Anatomy 0.000 claims 2
- 210000002784 stomach Anatomy 0.000 claims 2
- 210000001541 thymus gland Anatomy 0.000 claims 2
- 210000001685 thyroid gland Anatomy 0.000 claims 2
- 238000013334 tissue model Methods 0.000 claims 2
- 210000003932 urinary bladder Anatomy 0.000 claims 2
- 241000269350 Anura Species 0.000 claims 1
- 241000271566 Aves Species 0.000 claims 1
- 241000283690 Bos taurus Species 0.000 claims 1
- 241000282693 Cercopithecidae Species 0.000 claims 1
- 241000282994 Cervidae Species 0.000 claims 1
- 241000283073 Equus caballus Species 0.000 claims 1
- 241000699666 Mus <mouse, genus> Species 0.000 claims 1
- 241000699670 Mus sp. Species 0.000 claims 1
- 241000282577 Pan troglodytes Species 0.000 claims 1
- 241001504519 Papio ursinus Species 0.000 claims 1
- 102000014961 Protein Precursors Human genes 0.000 claims 1
- 108010078762 Protein Precursors Proteins 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 241000282898 Sus scrofa Species 0.000 claims 1
- 210000003815 abdominal wall Anatomy 0.000 claims 1
- 230000001919 adrenal effect Effects 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 210000001367 artery Anatomy 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 210000003651 basophil Anatomy 0.000 claims 1
- 210000001772 blood platelet Anatomy 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 210000000133 brain stem Anatomy 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 210000003123 bronchiole Anatomy 0.000 claims 1
- 230000005907 cancer growth Effects 0.000 claims 1
- 210000003169 central nervous system Anatomy 0.000 claims 1
- 210000003679 cervix uteri Anatomy 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 239000000084 colloidal system Substances 0.000 claims 1
- 230000001085 cytostatic effect Effects 0.000 claims 1
- 230000001472 cytotoxic effect Effects 0.000 claims 1
- 230000002526 effect on cardiovascular system Effects 0.000 claims 1
- 230000002500 effect on skin Effects 0.000 claims 1
- 230000002124 endocrine Effects 0.000 claims 1
- 210000003979 eosinophil Anatomy 0.000 claims 1
- 210000002615 epidermis Anatomy 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 210000003020 exocrine pancreas Anatomy 0.000 claims 1
- 230000003325 follicular Effects 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 210000005095 gastrointestinal system Anatomy 0.000 claims 1
- 230000000762 glandular Effects 0.000 claims 1
- 210000003714 granulocyte Anatomy 0.000 claims 1
- 210000004884 grey matter Anatomy 0.000 claims 1
- 210000000777 hematopoietic system Anatomy 0.000 claims 1
- 210000003630 histaminocyte Anatomy 0.000 claims 1
- 210000003405 ileum Anatomy 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 210000001630 jejunum Anatomy 0.000 claims 1
- 210000002540 macrophage Anatomy 0.000 claims 1
- 238000012423 maintenance Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000035800 maturation Effects 0.000 claims 1
- 210000003593 megakaryocyte Anatomy 0.000 claims 1
- 210000001259 mesencephalon Anatomy 0.000 claims 1
- 210000005033 mesothelial cell Anatomy 0.000 claims 1
- 210000002346 musculoskeletal system Anatomy 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 210000004498 neuroglial cell Anatomy 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 claims 1
- 210000000440 neutrophil Anatomy 0.000 claims 1
- 230000008520 organization Effects 0.000 claims 1
- 210000000963 osteoblast Anatomy 0.000 claims 1
- 210000002997 osteoclast Anatomy 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 210000003101 oviduct Anatomy 0.000 claims 1
- 210000002741 palatine tonsil Anatomy 0.000 claims 1
- 210000000496 pancreas Anatomy 0.000 claims 1
- 230000000849 parathyroid Effects 0.000 claims 1
- 210000003516 pericardium Anatomy 0.000 claims 1
- 210000004976 peripheral blood cell Anatomy 0.000 claims 1
- 210000000578 peripheral nerve Anatomy 0.000 claims 1
- 210000001428 peripheral nervous system Anatomy 0.000 claims 1
- 210000002826 placenta Anatomy 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 238000011363 radioimmunotherapy Methods 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 238000007423 screening assay Methods 0.000 claims 1
- 210000002027 skeletal muscle Anatomy 0.000 claims 1
- 210000000813 small intestine Anatomy 0.000 claims 1
- 210000000278 spinal cord Anatomy 0.000 claims 1
- 210000001550 testis Anatomy 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000000626 ureter Anatomy 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
- 210000001635 urinary tract Anatomy 0.000 claims 1
- 210000002229 urogenital system Anatomy 0.000 claims 1
- 210000004291 uterus Anatomy 0.000 claims 1
- 210000001215 vagina Anatomy 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
- 210000004885 white matter Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38471502P | 2002-05-30 | 2002-05-30 | |
| PCT/US2003/017285 WO2003101187A1 (en) | 2002-05-30 | 2003-05-30 | Animal model for toxicology and dose prediction |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005527226A JP2005527226A (ja) | 2005-09-15 |
| JP2005527226A5 true JP2005527226A5 (https=) | 2006-03-16 |
| JP4304309B2 JP4304309B2 (ja) | 2009-07-29 |
Family
ID=29712081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004508558A Expired - Fee Related JP4304309B2 (ja) | 2002-05-30 | 2003-05-30 | 毒物学および投薬予測のための動物モデル |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20040045045A1 (https=) |
| EP (1) | EP1507454A4 (https=) |
| JP (1) | JP4304309B2 (https=) |
| KR (1) | KR20050004263A (https=) |
| CN (1) | CN1655671A (https=) |
| AU (1) | AU2003249675B2 (https=) |
| CA (1) | CA2486548A1 (https=) |
| IL (2) | IL165128A (https=) |
| MX (1) | MXPA04011828A (https=) |
| NZ (1) | NZ536553A (https=) |
| WO (1) | WO2003101187A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7148038B2 (en) * | 2001-10-16 | 2006-12-12 | Raven Biotechnologies, Inc. | Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof |
| GB0427916D0 (en) * | 2004-12-21 | 2005-01-19 | Astrazeneca Ab | Method |
| RU2325641C1 (ru) * | 2006-11-20 | 2008-05-27 | Наталья Александровна Уракова | Способ экспресс-оценки степени безопасности лекарственных средств для инъекций |
| US8628554B2 (en) | 2010-06-13 | 2014-01-14 | Virender K. Sharma | Intragastric device for treating obesity |
| US9526648B2 (en) | 2010-06-13 | 2016-12-27 | Synerz Medical, Inc. | Intragastric device for treating obesity |
| US10010439B2 (en) | 2010-06-13 | 2018-07-03 | Synerz Medical, Inc. | Intragastric device for treating obesity |
| US10420665B2 (en) | 2010-06-13 | 2019-09-24 | W. L. Gore & Associates, Inc. | Intragastric device for treating obesity |
| EP3332814B1 (en) * | 2015-08-03 | 2024-11-06 | FUJIFILM Corporation | Cell structure, rodent model animal, method for producing rodent model animal, and method for evaluating test substance |
| US10779980B2 (en) | 2016-04-27 | 2020-09-22 | Synerz Medical, Inc. | Intragastric device for treating obesity |
| KR101920048B1 (ko) * | 2016-10-17 | 2018-11-19 | 건국대학교 산학협력단 | 피부 독성 평가용 지렁이 동물모델 및 이를 이용한 인간 피부 독성 평가방법 |
| JP7478720B2 (ja) * | 2018-04-13 | 2024-05-07 | シャンハイ エルアイディーイー バイオテック カンパニー リミテッド | 条件付き再プログラム化細胞から動物モデルを得るための方法および抗腫瘍薬のスクリーニングのための動物モデルの使用 |
| CN114711192B (zh) * | 2022-04-13 | 2022-11-29 | 中国科学院西北高原生物研究所 | 一种长效抑郁症动物模型的构建试剂盒及构建方法 |
| CN117016488B (zh) * | 2023-08-16 | 2025-09-16 | 中国水产科学研究院淡水渔业研究中心 | 一种大口黑鲈xy型遗传雄鱼性反转为xy型伪雌鱼的诱导剂及诱导方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5476996A (en) * | 1988-06-14 | 1995-12-19 | Lidak Pharmaceuticals | Human immune system in non-human animal |
| KR950701230A (ko) * | 1993-03-04 | 1995-03-23 | 죤제이 쉬바르츠 | 작은 동물 전이모델(small animal metastasis model) |
| US5698413A (en) * | 1993-05-05 | 1997-12-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method of evaluating chemotherapeutic agents in vivo |
| US6416999B1 (en) * | 2000-04-07 | 2002-07-09 | Raven Biotechnologies, Inc. | Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof |
| US6436704B1 (en) * | 2000-04-10 | 2002-08-20 | Raven Biotechnologies, Inc. | Human pancreatic epithelial progenitor cells and methods of isolation and use thereof |
-
2003
- 2003-05-30 MX MXPA04011828A patent/MXPA04011828A/es active IP Right Grant
- 2003-05-30 JP JP2004508558A patent/JP4304309B2/ja not_active Expired - Fee Related
- 2003-05-30 EP EP03756340A patent/EP1507454A4/en not_active Withdrawn
- 2003-05-30 CA CA002486548A patent/CA2486548A1/en not_active Abandoned
- 2003-05-30 AU AU2003249675A patent/AU2003249675B2/en not_active Ceased
- 2003-05-30 WO PCT/US2003/017285 patent/WO2003101187A1/en not_active Ceased
- 2003-05-30 US US10/448,766 patent/US20040045045A1/en not_active Abandoned
- 2003-05-30 CN CNA038124866A patent/CN1655671A/zh active Pending
- 2003-05-30 KR KR10-2004-7019377A patent/KR20050004263A/ko not_active Ceased
- 2003-05-30 NZ NZ536553A patent/NZ536553A/en not_active IP Right Cessation
-
2004
- 2004-11-09 IL IL165128A patent/IL165128A/en not_active IP Right Cessation
-
2010
- 2010-08-12 IL IL207587A patent/IL207587A/en not_active IP Right Cessation
-
2012
- 2012-01-11 US US13/348,479 patent/US20120110682A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Arnold | The evolution of marmot sociality: I. Why disperse late? | |
| Goodson | Territorial aggression and dawn song are modulated by septal vasotocin and vasoactive intestinal polypeptide in male field sparrows (Spizella pusilla) | |
| Menger et al. | Scope and perspectives of intravital microscopy-bridge over from in vitro to in vivo | |
| Adamec et al. | Unilateral block of NMDA receptors in the amygdala prevents predator stress-induced lasting increases in anxiety-like behavior and unconditioned startle—effective hemisphere depends on the behavior | |
| Yap et al. | Repeated brief social defeat episodes in mice: effects on cell proliferation in the dentate gyrus | |
| JP2005527226A5 (https=) | ||
| US20120110682A1 (en) | Animal Model for Toxicology and Dose Prediction | |
| USRE39337E1 (en) | Nude mouse model for human neoplastic disease | |
| JPH05227861A (ja) | 非ヒトキメラ細胞 | |
| Bildsøe et al. | Stereotypies in female ranch mink: seasonal and diurnal variations | |
| Julien et al. | Tracking gonadotropin-releasing hormone-mediated movement in-vivo using quantum dot nanoparticles: insights into pathways leading to sperm release | |
| Stan | Macroscopic anatomy of the gallbladder and extrahepatic biliary tract in the guinea pig (Cavia porcellus). | |
| CN101406695A (zh) | 促进脊髓损伤中轴突再生和行为功能恢复的药物组合物 | |
| Michaely et al. | First report about a cerebrospinal nematode infection in an alpaca (Vicugna pacos) | |
| KR20160116750A (ko) | 침샘 조직 이식을 통한 쇼그렌 증후군 동물모델인 “아바타스”의 제조방법 | |
| Wernick et al. | Pathology in practice | |
| JP7425485B2 (ja) | 疾患モデル | |
| JP3964278B2 (ja) | 肝硬変モデル動物およびその作製方法 | |
| Contreras et al. | Experimental Animal Models in Research: Diabetes and Impaired Wound Healing | |
| KR20240078385A (ko) | 암환자 면역모사 아바타 시스템을 이용한 면역항암제 평가플랫폼 | |
| Walter | The evolution of marmot sociality: I. Why disperse late? | |
| Shendryk et al. | STRONGYLOIDIASIS OF RUMINANTS OF THE STEPPE ZONE OF UKRAINE | |
| WO2000011943A1 (en) | Post-pubertary amygdala lesions as animals models for cns disorders | |
| Waters et al. | Clues | |
| Vinke et al. | Ferrets furo) putorius (Mustela |