JP4221289B2 - 核酸アジュバント - Google Patents

核酸アジュバント Download PDF

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Publication number
JP4221289B2
JP4221289B2 JP2003510065A JP2003510065A JP4221289B2 JP 4221289 B2 JP4221289 B2 JP 4221289B2 JP 2003510065 A JP2003510065 A JP 2003510065A JP 2003510065 A JP2003510065 A JP 2003510065A JP 4221289 B2 JP4221289 B2 JP 4221289B2
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JP
Japan
Prior art keywords
nucleic acid
subunit
antigen
dna
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2003510065A
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English (en)
Japanese (ja)
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JP2004536107A (ja
JP2004536107A5 (enExample
Inventor
ヘインズ，ジョエル，アール．
アーリントン，ジョシュア，イー．
Original Assignee
パウダージェクト バクシーンズ，インコーポレイテッド
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Publication of JP2004536107A publication Critical patent/JP2004536107A/ja
Publication of JP2004536107A5 publication Critical patent/JP2004536107A5/ja
Application granted granted Critical
Publication of JP4221289B2 publication Critical patent/JP4221289B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2003510065A 2000-11-27 2001-11-26 核酸アジュバント Expired - Fee Related JP4221289B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72431500A 2000-11-27 2000-11-27
PCT/US2001/043151 WO2003004055A2 (en) 2000-11-27 2001-11-26 Nucleic acid adjuvants

Publications (3)

Publication Number Publication Date
JP2004536107A JP2004536107A (ja) 2004-12-02
JP2004536107A5 JP2004536107A5 (enExample) 2005-12-22
JP4221289B2 true JP4221289B2 (ja) 2009-02-12

Family

ID=24909936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003510065A Expired - Fee Related JP4221289B2 (ja) 2000-11-27 2001-11-26 核酸アジュバント

Country Status (16)

Country Link
EP (1) EP1379273B1 (enExample)
JP (1) JP4221289B2 (enExample)
KR (1) KR20040045391A (enExample)
CN (1) CN1317034C (enExample)
AT (1) ATE442858T1 (enExample)
AU (1) AU2001297988B2 (enExample)
BR (1) BR0115646A (enExample)
CA (1) CA2429708A1 (enExample)
DE (1) DE60139959D1 (enExample)
DK (1) DK1379273T3 (enExample)
ES (1) ES2332261T3 (enExample)
IL (2) IL156041A0 (enExample)
MX (1) MXPA03004638A (enExample)
NZ (1) NZ526175A (enExample)
PT (1) PT1379273E (enExample)
WO (1) WO2003004055A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101225395B1 (ko) 2003-10-10 2013-01-28 파우더젝트 백신, 인코포레이티드 핵산 구조물
BRPI0507579A (pt) 2004-02-11 2007-07-03 Angeletti P Ist Richerche Bio molécula de ácido nucleico, vetor, célula hospedeira, processo para expressar uma proteìna de fusão cea em uma célula hospedeira recombinante, proteìna de fusão cea purificada, método de prevenção ou tratamento de cáncer, plasmìdeo de vacina, e, método de tratamento de um mamìfero sofrendo de ou predisposto a um cáncer associados com cea
GB0507997D0 (en) * 2005-02-01 2005-05-25 Powderject Vaccines Inc Nucleic acid constructs
US8389686B2 (en) 2008-05-07 2013-03-05 Osaka University Noncovalent collagen crosslinking agent
US11246915B2 (en) 2010-09-15 2022-02-15 Applied Molecular Transport Inc. Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
CA2848656C (en) 2010-09-15 2017-10-10 Randall J. Mrsny Systems and methods of delivery of bioactive agents using bacterial toxin-derived transport sequences
CN103060253A (zh) * 2013-01-24 2013-04-24 麻丽丹 霍乱弧菌ctxAB基因的质粒克隆菌株以及制备方法和应用
DK3139965T3 (da) 2014-05-07 2021-11-22 Applied Molecular Transport Inc Fusionsmolekyler afledt af cholix-toksin til oral indgivelse af biologisk aktive stoffer
EP4082558B1 (en) 2018-03-08 2023-08-23 Applied Molecular Transport Inc. Toxin-derived delivery constructs for oral delivery
KR20210110294A (ko) 2018-11-07 2021-09-07 어플라이드 몰레큘라 트랜스포트 인크. 통과세포외배출용 전달 구조체 및 관련 방법
BR112022002962A2 (pt) 2019-08-16 2022-07-05 Applied Molecular Transport Inc Composições, formulações e produção e purificação de interleucina

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219740A (en) 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
TW404844B (en) 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
GB9416663D0 (en) 1994-08-17 1994-10-12 Oxford Bioscience Limited Particle delivery
AU3703895A (en) 1994-10-24 1996-05-15 Oxford Biosciences Limited Particle delivery
GB9426379D0 (en) 1994-12-23 1995-03-01 Oxford Biosciences Ltd Particle delivery
US6056960A (en) * 1995-06-07 2000-05-02 Kaslow; Harvey R. Compositions exhibiting ADP-ribosyltransferase activity and methods for the preparation and use thereof
GB9612629D0 (en) 1996-06-17 1996-08-21 Oxford Biosciences Ltd Method for providing dense particle compositions for use in transdermal particle delivery
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization

Also Published As

Publication number Publication date
KR20040045391A (ko) 2004-06-01
EP1379273B1 (en) 2009-09-16
DE60139959D1 (de) 2009-10-29
CN1537013A (zh) 2004-10-13
BR0115646A (pt) 2005-12-13
MXPA03004638A (es) 2004-04-20
ES2332261T3 (es) 2010-02-01
WO2003004055A3 (en) 2003-11-20
JP2004536107A (ja) 2004-12-02
CN1317034C (zh) 2007-05-23
IL156041A0 (en) 2003-12-23
CA2429708A1 (en) 2003-01-16
ATE442858T1 (de) 2009-10-15
AU2001297988B2 (en) 2006-10-26
PT1379273E (pt) 2009-11-27
EP1379273A2 (en) 2004-01-14
NZ526175A (en) 2006-01-27
IL156041A (en) 2010-05-17
WO2003004055A2 (en) 2003-01-16
DK1379273T3 (da) 2009-11-09

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