JP4214239B2 - 二機能性レトロウイルス／アデノウイルス系 - Google Patents
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- JP4214239B2 JP4214239B2 JP52385598A JP52385598A JP4214239B2 JP 4214239 B2 JP4214239 B2 JP 4214239B2 JP 52385598 A JP52385598 A JP 52385598A JP 52385598 A JP52385598 A JP 52385598A JP 4214239 B2 JP4214239 B2 JP 4214239B2
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
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- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10344—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/13022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2810/6072—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
- C12N2810/6081—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3132396P | 1996-11-19 | 1996-11-19 | |
| US60/031,323 | 1996-11-19 | ||
| US3708197P | 1997-02-04 | 1997-02-04 | |
| US60/037,081 | 1997-02-04 | ||
| PCT/US1997/021169 WO1998022143A1 (en) | 1996-11-19 | 1997-11-19 | Chimeric retrovirus/adenovirus system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001509009A JP2001509009A (ja) | 2001-07-10 |
| JP2001509009A5 JP2001509009A5 (enExample) | 2005-03-10 |
| JP4214239B2 true JP4214239B2 (ja) | 2009-01-28 |
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| JP52385598A Expired - Fee Related JP4214239B2 (ja) | 1996-11-19 | 1997-11-19 | 二機能性レトロウイルス／アデノウイルス系 |
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| US20010006629A1 (en) * | 1993-10-25 | 2001-07-05 | Richard J. Gregory | Recombinant adenoviral vector and methods of use |
| AU687117B2 (en) * | 1993-10-25 | 1998-02-19 | Canji, Inc. | Recombinant adenoviral vector and methods of use |
| US6210939B1 (en) | 1993-10-25 | 2001-04-03 | Canji, Inc. | Recombinant adenoviral vector and methods of use |
| US20060275261A1 (en) * | 1993-10-25 | 2006-12-07 | Canji, Inc. | Adenoviral vectors having a protein IX deletion |
| JP2001518804A (ja) * | 1997-03-21 | 2001-10-16 | エンゾー セラピューティクス インコーポレイテッド | ベクターおよびウイルスベクター、およびこれらを増殖するためのパッケージング細胞株 |
| US8703480B1 (en) | 1997-03-21 | 2014-04-22 | Enzo Therapeutics, Inc. | Biological function effecting viral vectors and chimeric cells useful as packaging cell lines and target cells |
| AU6962698A (en) | 1997-04-11 | 1998-11-11 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Transgenomic viruses and the use thereof |
| WO1999044423A1 (en) * | 1998-03-03 | 1999-09-10 | The Uab Research Foundation | Amplification of gene transfer and gene therapy by controlled replication |
| US20060183228A1 (en) * | 1998-03-24 | 2006-08-17 | Enzo Therapeutics, Inc. | Viral vectors with surface or envelope components |
| FR2778670B1 (fr) | 1998-05-18 | 2002-12-13 | Rhone Poulenc Rorer Sa | Methodes et compositions pour la production de particules virales |
| AU6149099A (en) * | 1998-09-22 | 2000-04-10 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Replication deficient retroviral vector system and methods of using |
| US7052904B2 (en) | 2000-01-31 | 2006-05-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Hybrid adeno-retroviral vector for the transfection of cells |
| EP1287153B1 (en) | 2000-05-31 | 2009-09-30 | Human Gene Therapy Research Institute | Methods and compositions for efficient gene transfer using transcomplementary vectors |
| US7226779B2 (en) | 2001-01-30 | 2007-06-05 | The United States Of America As Represented By The Department Of Health And Human Services | Hybrid adenoviral vector |
| US7271150B2 (en) | 2001-05-14 | 2007-09-18 | United States Of America, Represented By The Secretary, Department Of Health And Human Services | Modified growth hormone |
| EP1442125A4 (en) * | 2001-10-04 | 2004-12-08 | Carlos Estuard Aguilar-Cordova | CHIMERAL VIRUS VECTORS FOR GENE THERAPY |
| US20070037284A1 (en) * | 2003-06-04 | 2007-02-15 | Enzo Therapeutics, Inc. | Vectors for expressing exogenous gene or exogenous nucleic acid sequences |
| ES2292271B1 (es) * | 2004-05-20 | 2009-02-16 | Proyecto De Biomedicina Cima, S.L. | Un vector hibrido adenovirus-alfavirus para la administracion eficaz y expresion de genes terapeuticos en celulas tumorales. |
| WO2011123518A1 (en) | 2010-03-31 | 2011-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adenosine receptor agonists for the treatment and prevention of vascular or joint capsule calcification disorders |
| WO2021108500A1 (en) | 2019-11-26 | 2021-06-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | T cell receptors targeting mutations in rna splicing factors |
| US20230348557A1 (en) | 2020-02-06 | 2023-11-02 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | T cell receptors Targeting Defective DNA Repair Proteins |
| US10822379B1 (en) | 2020-03-12 | 2020-11-03 | University of Pittsburgh—of the Commonwealth System of Higher Education | Molecules that bind to SARS-CoV-2 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997025446A1 (en) * | 1996-01-05 | 1997-07-17 | Genetic Therapy, Inc. | Recombinase-mediated generation of adenoviral vectors |
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- 1997-11-19 DE DE69733035T patent/DE69733035T2/de not_active Expired - Lifetime
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- 1997-11-19 AT AT97948396T patent/ATE292983T1/de not_active IP Right Cessation
- 1997-11-19 JP JP52385598A patent/JP4214239B2/ja not_active Expired - Fee Related
Also Published As
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| EP0956052A1 (en) | 1999-11-17 |
| AU5447598A (en) | 1998-06-10 |
| US6333030B1 (en) | 2001-12-25 |
| JP2001509009A (ja) | 2001-07-10 |
| WO1998022143A1 (en) | 1998-05-28 |
| EP0956052B1 (en) | 2005-04-13 |
| ATE292983T1 (de) | 2005-04-15 |
| CA2272121A1 (en) | 1998-05-28 |
| DE69733035T2 (de) | 2005-11-24 |
| AU728610B2 (en) | 2001-01-11 |
| DE69733035D1 (en) | 2005-05-19 |
| EP0956052A4 (en) | 2001-05-02 |
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