JP4073955B2 - アルツハイマー病に関連する第１染色体の遺伝子および遺伝子産物 - Google Patents
アルツハイマー病に関連する第１染色体の遺伝子および遺伝子産物 Download PDFInfo
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95695P | 1995-07-07 | 1995-07-07 | |
| US60/000,956 | 1995-07-07 | ||
| US167595P | 1995-07-28 | 1995-07-28 | |
| US60/001,675 | 1995-07-28 | ||
| US217495P | 1995-08-11 | 1995-08-11 | |
| US60/002,174 | 1995-08-11 | ||
| US232895P | 1995-08-14 | 1995-08-14 | |
| US60/002,328 | 1995-08-14 | ||
| PCT/US1996/011386 WO1997003192A2 (en) | 1995-07-07 | 1996-07-05 | Chromosome 1 gene and gene products related to alzheimer's disease |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007206901A Division JP2008035863A (ja) | 1995-07-07 | 2007-08-08 | アルツハイマー病に関連する変異ａｄ４タンパク質の利用 |
| JP2007206900A Division JP2008035862A (ja) | 1995-07-07 | 2007-08-08 | アルツハイマー病に関連する変異ａｄ４タンパク質 |
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| Publication Number | Publication Date |
|---|---|
| JP2001517922A JP2001517922A (ja) | 2001-10-09 |
| JP2001517922A5 JP2001517922A5 (enExample) | 2004-08-19 |
| JP4073955B2 true JP4073955B2 (ja) | 2008-04-09 |
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| JP50592597A Expired - Fee Related JP4073955B2 (ja) | 1995-07-07 | 1996-07-05 | アルツハイマー病に関連する第１染色体の遺伝子および遺伝子産物 |
| JP2007206900A Withdrawn JP2008035862A (ja) | 1995-07-07 | 2007-08-08 | アルツハイマー病に関連する変異ａｄ４タンパク質 |
| JP2007206901A Withdrawn JP2008035863A (ja) | 1995-07-07 | 2007-08-08 | アルツハイマー病に関連する変異ａｄ４タンパク質の利用 |
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| JP2007206900A Withdrawn JP2008035862A (ja) | 1995-07-07 | 2007-08-08 | アルツハイマー病に関連する変異ａｄ４タンパク質 |
| JP2007206901A Withdrawn JP2008035863A (ja) | 1995-07-07 | 2007-08-08 | アルツハイマー病に関連する変異ａｄ４タンパク質の利用 |
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| EP (2) | EP1637600A1 (enExample) |
| JP (3) | JP4073955B2 (enExample) |
| AT (1) | ATE305039T1 (enExample) |
| CA (1) | CA2226255A1 (enExample) |
| DE (1) | DE69635207T2 (enExample) |
| WO (1) | WO1997003192A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5986054A (en) * | 1995-04-28 | 1999-11-16 | The Hospital For Sick Children, Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
| JP5379119B2 (ja) * | 1995-04-28 | 2013-12-25 | エイチエスシー リサーチ アンド ディベロップメント リミテッド | アルツハイマー病に関連する遺伝子配列およびタンパク質、ならびにその使用 |
| US6531586B1 (en) | 1995-04-28 | 2003-03-11 | The Hospital For Sick Children | Genetic sequences related to Alzheimer's Disease |
| US6210919B1 (en) | 1995-04-28 | 2001-04-03 | Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
| WO1997007213A2 (en) * | 1995-08-16 | 1997-02-27 | President And Fellows Of Harvard College | Assay for identifying genes causing chromosome non-disjunction |
| JP2000506375A (ja) * | 1996-01-26 | 2000-05-30 | エイチエスシー リサーチ アンド デベロップメント リミテッド パートナーシップ | アルツハイマー病に関連する核酸およびタンパク質、ならびにその使用 |
| ES2128265B1 (es) * | 1997-06-04 | 2000-03-01 | Euroespes S A | Kit genetico para la caracterizacion molecular de la enfermedad de alzheimer. |
| US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
| US7588766B1 (en) | 2000-05-26 | 2009-09-15 | Elan Pharma International Limited | Treatment of amyloidogenic disease |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| US6761888B1 (en) | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
| WO1999035501A1 (en) | 1998-01-09 | 1999-07-15 | The Governing Council Of The University Of Toronto | Presenilin protein interactions |
| TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
| JP2003018991A (ja) * | 2001-06-27 | 2003-01-21 | Japan Science & Technology Corp | プレセニリン−２遺伝子エキソン５欠損型スプライシング異常の生成に関与する核酸 |
| MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| TWI306458B (en) | 2003-05-30 | 2009-02-21 | Elan Pharma Int Ltd | Humanized antibodies that recognize beta amyloid peptide |
| ES2396555T3 (es) | 2004-12-15 | 2013-02-22 | Janssen Alzheimer Immunotherapy | Anticuerpos que reconocen péptido beta amiloide |
| ES2434732T3 (es) | 2004-12-15 | 2013-12-17 | Janssen Alzheimer Immunotherapy | Anticuerpos para beta-amiloide humanizados para su uso en mejorar la cognición |
| US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
| JP5124569B2 (ja) * | 2006-06-12 | 2013-01-23 | カー−バー インヴェストメンツ インコーポレイテッド | ノズル検査装置および方法 |
| US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
| SI2182983T1 (sl) | 2007-07-27 | 2014-09-30 | Janssen Alzheimer Immunotherapy | Zdravljenje amiloidogenih bolezni s humaniziranimi protitelesi proti abeta |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
| WO2013092052A1 (en) * | 2011-12-20 | 2013-06-27 | Unilever Plc | Isotropic liquid detergents comprising soil release polymer |
| WO2019023247A1 (en) | 2017-07-25 | 2019-01-31 | Immutics, Inc. | TREATMENT OF CANCER BY BLOCKING THE INTERACTION OF TIM-3 AND ITS LIGAND |
| EP3918323A4 (en) | 2019-01-30 | 2022-12-28 | TrueBinding, Inc. | ANTI-GAL3 ANTIBODIES AND USES THEREOF |
| WO2021242776A2 (en) | 2020-05-26 | 2021-12-02 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking galectin-3 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6210919B1 (en) * | 1995-04-28 | 2001-04-03 | Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
| US5986054A (en) * | 1995-04-28 | 1999-11-16 | The Hospital For Sick Children, Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
-
1996
- 1996-07-05 JP JP50592597A patent/JP4073955B2/ja not_active Expired - Fee Related
- 1996-07-05 CA CA002226255A patent/CA2226255A1/en not_active Abandoned
- 1996-07-05 EP EP05015005A patent/EP1637600A1/en not_active Withdrawn
- 1996-07-05 EP EP96926062A patent/EP0846171B1/en not_active Expired - Lifetime
- 1996-07-05 DE DE69635207T patent/DE69635207T2/de not_active Expired - Lifetime
- 1996-07-05 WO PCT/US1996/011386 patent/WO1997003192A2/en not_active Ceased
- 1996-07-05 AT AT96926062T patent/ATE305039T1/de not_active IP Right Cessation
-
1999
- 1999-08-16 US US09/375,318 patent/US6468791B1/en not_active Expired - Fee Related
-
2002
- 2002-06-24 US US10/180,781 patent/US20030180880A1/en not_active Abandoned
-
2007
- 2007-08-08 JP JP2007206900A patent/JP2008035862A/ja not_active Withdrawn
- 2007-08-08 JP JP2007206901A patent/JP2008035863A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997003192A3 (en) | 1997-04-03 |
| JP2008035863A (ja) | 2008-02-21 |
| US6468791B1 (en) | 2002-10-22 |
| EP1637600A1 (en) | 2006-03-22 |
| JP2008035862A (ja) | 2008-02-21 |
| DE69635207D1 (de) | 2006-02-02 |
| EP0846171B1 (en) | 2005-09-21 |
| DE69635207T2 (de) | 2006-06-22 |
| EP0846171A2 (en) | 1998-06-10 |
| JP2001517922A (ja) | 2001-10-09 |
| US20030180880A1 (en) | 2003-09-25 |
| CA2226255A1 (en) | 1997-01-30 |
| WO1997003192A2 (en) | 1997-01-30 |
| ATE305039T1 (de) | 2005-10-15 |
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