JP4058114B2 - クラリスロマイシンの結晶形態０ - Google Patents

クラリスロマイシンの結晶形態０ Download PDF

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Publication number
JP4058114B2
JP4058114B2 JP53437298A JP53437298A JP4058114B2 JP 4058114 B2 JP4058114 B2 JP 4058114B2 JP 53437298 A JP53437298 A JP 53437298A JP 53437298 A JP53437298 A JP 53437298A JP 4058114 B2 JP4058114 B2 JP 4058114B2
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JP
Japan
Prior art keywords
methylerythromycin
solvate
powder
ray diffraction
peak
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP53437298A
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English (en)
Japanese (ja)
Other versions
JP2000509725A (ja
Inventor
スパントン，ステイーブン・ジイ
ヘンリー，ロジヤー・エフ
リリー，デイビツド・エイ
リウ，チー−ホウア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25136084&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4058114(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2000509725A publication Critical patent/JP2000509725A/ja
Application granted granted Critical
Publication of JP4058114B2 publication Critical patent/JP4058114B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
JP53437298A 1997-01-17 1997-12-19 クラリスロマイシンの結晶形態０ Expired - Lifetime JP4058114B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/785,623 1997-01-17
US08/785,623 US5945405A (en) 1997-01-17 1997-01-17 Crystal form O of clarithromycin
PCT/US1997/023607 WO1998031699A1 (en) 1997-01-17 1997-12-19 Crystal form 0 of clarithromycin

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2003311358A Division JP2004075689A (ja) 1997-01-17 2003-09-03 クラリスロマイシンの結晶形態０

Publications (2)

Publication Number Publication Date
JP2000509725A JP2000509725A (ja) 2000-08-02
JP4058114B2 true JP4058114B2 (ja) 2008-03-05

Family

ID=25136084

Family Applications (3)

Application Number Title Priority Date Filing Date
JP53437298A Expired - Lifetime JP4058114B2 (ja) 1997-01-17 1997-12-19 クラリスロマイシンの結晶形態０
JP2003311358A Withdrawn JP2004075689A (ja) 1997-01-17 2003-09-03 クラリスロマイシンの結晶形態０
JP2008327022A Expired - Lifetime JP5190350B2 (ja) 1997-01-17 2008-12-24 クラリスロマイシンの結晶形態０

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2003311358A Withdrawn JP2004075689A (ja) 1997-01-17 2003-09-03 クラリスロマイシンの結晶形態０
JP2008327022A Expired - Lifetime JP5190350B2 (ja) 1997-01-17 2008-12-24 クラリスロマイシンの結晶形態０

Country Status (18)

Country Link
US (1) US5945405A (https=)
EP (1) EP1077988A1 (https=)
JP (3) JP4058114B2 (https=)
KR (1) KR100567149B1 (https=)
CN (1) CN1174991C (https=)
AR (3) AR011077A1 (https=)
AU (1) AU735598B2 (https=)
BR (1) BR9714287A (https=)
CA (4) CA2419499A1 (https=)
CZ (1) CZ297433B6 (https=)
DE (1) DE97951771T1 (https=)
ES (1) ES2173058T1 (https=)
IL (1) IL130255A0 (https=)
NZ (1) NZ336073A (https=)
TR (1) TR199901578T2 (https=)
TW (1) TW574224B (https=)
WO (1) WO1998031699A1 (https=)
ZA (1) ZA98116B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009137975A (ja) * 1997-01-17 2009-06-25 Abbott Lab クラリスロマイシンの結晶形態０

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KR100377159B1 (ko) * 1998-09-09 2003-08-19 한미약품공업 주식회사 잔류 용매가 없는 클라리스로마이신의 결정형 2의 제조 방법
GB9827355D0 (en) * 1998-12-11 1999-02-03 Biochemie Sa Organic compounds
KR100322313B1 (ko) * 1999-10-21 2002-02-06 민경윤 클라리스로마이신 결정형 2의 제조방법 및 이에 사용되는 클라리스로마이신 포르메이트
US6627743B1 (en) * 1999-12-03 2003-09-30 Abbott Laboratories 6-O-methylerythromycin A crystal form III
AU783055B2 (en) * 1999-12-16 2005-09-22 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin polymorphs and novel polymorph IV
FR2802534B1 (fr) * 1999-12-20 2002-02-01 Merial Sas Procede pour preparer et isoler la 9-deoxo-9 (z)- hydroxyiminoerythromycine a
RU2002118308A (ru) 2000-01-11 2004-02-20 Тева Фамэситикл Индастрис Лтд. (Il) Способы получения полиморфных модификаций кларитромицина
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
HUP0302466A2 (hu) * 2000-02-29 2003-11-28 Teva Pharmaceutical Industries Ltd. Eljárások clarithromycin, clarithromycin intermedier, gyakorlatilag oximmentes clarithromycin és ezt tartalmazó gyógyszerkészítmény előállítására
ATE297941T1 (de) * 2000-03-15 2005-07-15 Hanmi Pharm Ind Co Ltd Verfahren zur herstellung von einer kristallinen form ii von clarythromycin
KR100367981B1 (ko) * 2000-11-23 2003-01-14 한미약품공업 주식회사 클라리스로마이신 결정형 2의 제조 방법 및 이 방법에사용되는 결정성 클라리스로마이신 메실레이트 삼수화물
BR0109544A (pt) * 2000-03-28 2003-06-10 Biochemie Gmbh Partìculas granuladas com sabor ocultado
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
US7198801B2 (en) * 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
US20070225379A1 (en) * 2001-08-03 2007-09-27 Carrara Dario Norberto R Transdermal delivery of systemically active central nervous system drugs
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US20040198706A1 (en) * 2003-03-11 2004-10-07 Carrara Dario Norberto R. Methods and formulations for transdermal or transmucosal application of active agents
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
KR100408848B1 (ko) * 2001-03-12 2003-12-06 주식회사 씨트리 클래리스로마이신의 정제방법
RU2217160C2 (ru) * 2001-04-20 2003-11-27 Челябинская государственная медицинская академия Способ местного лечения урогенитального хламидиоза у женщин
JP2004537566A (ja) * 2001-08-01 2004-12-16 ブリストル−マイヤーズ　スクイブ　カンパニー 味マスキング組成物
TW200302830A (en) * 2002-01-11 2003-08-16 Chugai Pharmaceutical Co Ltd Anhydrate/hydrate of an erythromycin derivative and processes for preparing said anhydrate/hydrate
CN100427498C (zh) * 2003-03-02 2008-10-22 王凌峰 克拉霉素a型结晶
US20040185092A1 (en) * 2003-03-18 2004-09-23 Yih Ming Hsiao Pharmaceutical preparations of omeprazole and/or clarithromycin for oral use
WO2005009365A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CA2533358C (en) 2003-07-21 2014-03-11 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2004258953B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
US8758820B2 (en) 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8246996B2 (en) * 2003-08-29 2012-08-21 Shionogi Inc. Antibiotic product, use and formulation thereof
JP2007513869A (ja) 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
DK1670433T3 (da) 2003-10-10 2012-03-12 Ferring Bv Transdermal farmaceutisk formulering til mindskelse af hudrester
US8715727B2 (en) 2004-07-02 2014-05-06 Shionogi Inc. Tablet for pulsed delivery
US20060111560A1 (en) * 2004-11-01 2006-05-25 Glenmark Pharmaceuticals Limited Process for the preparation of crystalline form II of clarithromycin
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
CA2614412A1 (en) * 2005-07-07 2007-01-18 Elan Pharma International, Limited Nanoparticulate clarithromycin formulations
WO2007036951A2 (en) * 2005-08-31 2007-04-05 Alembic Limited Process to obtain 6-o-methylerythromycin a (clarithromycin)_form ii
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
CA2646667C (en) 2006-04-21 2014-03-11 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2008067991A2 (en) * 2006-12-08 2008-06-12 Antares Pharma Ipl Ag Skin-friendly drug complexes for transdermal administration
DE102007016367A1 (de) 2007-04-03 2008-10-09 Grünenthal GmbH Polymorph von Clarithromycin (Form V)
WO2009023191A2 (en) * 2007-08-09 2009-02-19 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of clarithromycin
EP2030613A1 (en) 2007-08-17 2009-03-04 Abbott GmbH & Co. KG Preparation of compositions with essentially noncrystalline embedded macrolide antibiotics
US9119769B2 (en) 2011-12-30 2015-09-01 The Curators Of The University Of Missouri Method for transforming pharmaceutical crystal forms
CN103087130B (zh) * 2013-02-06 2015-12-23 浙江国邦药业有限公司 一种克拉霉素晶型转换方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009137975A (ja) * 1997-01-17 2009-06-25 Abbott Lab クラリスロマイシンの結晶形態０

Also Published As

Publication number Publication date
KR100567149B1 (ko) 2006-04-04
AU735598B2 (en) 2001-07-12
AR039667A2 (es) 2005-03-02
EP1077988A1 (en) 2001-02-28
JP5190350B2 (ja) 2013-04-24
CA2419499A1 (en) 1998-07-23
DE97951771T1 (de) 2004-07-08
JP2009137975A (ja) 2009-06-25
AU5532698A (en) 1998-08-07
CA2387356A1 (en) 1998-07-23
CA2277274C (en) 2003-05-27
TR199901578T2 (xx) 1999-09-21
US5945405A (en) 1999-08-31
TW574224B (en) 2004-02-01
AR011077A1 (es) 2000-08-02
CN1174991C (zh) 2004-11-10
ES2173058T1 (es) 2002-10-16
CA2387361C (en) 2003-05-27
JP2000509725A (ja) 2000-08-02
CA2277274A1 (en) 1998-07-23
CA2387356C (en) 2003-05-27
JP2004075689A (ja) 2004-03-11
KR20000070220A (ko) 2000-11-25
CN1244869A (zh) 2000-02-16
WO1998031699A1 (en) 1998-07-23
CZ242699A3 (cs) 1999-11-17
IL130255A0 (en) 2000-06-01
CA2387361A1 (en) 1998-07-23
BR9714287A (pt) 2000-04-18
NZ336073A (en) 2001-01-26
ZA98116B (en) 1998-07-08
CZ297433B6 (cs) 2006-12-13
AR039666A2 (es) 2005-03-02

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