JP4050317B2 - Il−10含有医薬組成物 - Google Patents
Il−10含有医薬組成物 Download PDFInfo
- Publication number
- JP4050317B2 JP4050317B2 JP50824697A JP50824697A JP4050317B2 JP 4050317 B2 JP4050317 B2 JP 4050317B2 JP 50824697 A JP50824697 A JP 50824697A JP 50824697 A JP50824697 A JP 50824697A JP 4050317 B2 JP4050317 B2 JP 4050317B2
- Authority
- JP
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- Prior art keywords
- wounds
- wound
- pharmaceutical composition
- healing
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Invalid Beds And Related Equipment (AREA)
- Eye Examination Apparatus (AREA)
- Prostheses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9516287.1 | 1995-08-09 | ||
| GB9516287A GB2304047A (en) | 1995-08-09 | 1995-08-09 | Pharmaceutical compositions containing cytokines |
| PCT/GB1996/001930 WO1997005894A1 (en) | 1995-08-09 | 1996-08-08 | Pharmaceutical composition containing il-10 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH11510505A JPH11510505A (ja) | 1999-09-14 |
| JPH11510505A5 JPH11510505A5 (enExample) | 2004-09-09 |
| JP4050317B2 true JP4050317B2 (ja) | 2008-02-20 |
Family
ID=10778967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50824697A Expired - Fee Related JP4050317B2 (ja) | 1995-08-09 | 1996-08-08 | Il−10含有医薬組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6387364B1 (enExample) |
| EP (1) | EP0871473B1 (enExample) |
| JP (1) | JP4050317B2 (enExample) |
| AT (1) | ATE229814T1 (enExample) |
| AU (1) | AU719089B2 (enExample) |
| CA (1) | CA2229078C (enExample) |
| DE (1) | DE69625516T2 (enExample) |
| DK (1) | DK0871473T3 (enExample) |
| ES (1) | ES2187665T3 (enExample) |
| GB (1) | GB2304047A (enExample) |
| PT (1) | PT871473E (enExample) |
| WO (1) | WO1997005894A1 (enExample) |
| ZA (1) | ZA966744B (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001505219A (ja) * | 1996-12-04 | 2001-04-17 | ザ・ビクトリア・ユニバーシティ・オブ・マンチェスター | 創傷の治癒および線維症の治療 |
| WO1998033516A1 (en) * | 1997-02-05 | 1998-08-06 | Schering Corporation | Use of il-4 and/or il-10 to treat proliferative glomerulonephritis |
| AU6951300A (en) * | 1999-09-08 | 2001-04-10 | Schering Corporation | Novel uses of mammalian ccr6 receptors and related reagents |
| US20060258562A1 (en) * | 2000-07-31 | 2006-11-16 | Healor Ltd. | Methods and pharmaceutical compositions for healing wounds |
| ATE516820T1 (de) | 2000-09-29 | 2011-08-15 | Schering Corp | Pegyliertes interleukin 10 |
| WO2003062373A2 (en) * | 2001-10-18 | 2003-07-31 | The Children's Hospital Of Philadelphia | Methods and materials for the recruitment of endothelial cells |
| JP4790609B2 (ja) * | 2003-07-15 | 2011-10-12 | バーイラン ユニバーシティー | 創傷治癒のための方法及び薬剤組成物 |
| WO2005013885A2 (en) | 2003-08-07 | 2005-02-17 | Healor Ltd. | Pharmaceutical compositions and methods for accelerating wound healing |
| GB0500643D0 (en) * | 2005-01-13 | 2005-02-23 | Renovo Ltd | Medicaments |
| GB0524103D0 (en) * | 2005-11-26 | 2006-01-04 | Medical Res Council | Healing |
| NO346530B1 (no) | 2006-09-28 | 2022-09-26 | Merck Sharp & Dohme | Anvendelser av pegylert interleukin-10 (PEG-IL-10) for å forebygge metastaser av kreft eller tumor i lungene. |
| KR20150072458A (ko) | 2006-11-15 | 2015-06-29 | 코다 테라퓨틱스, 인크. | 상처 치유를 위한 개선 방법 및 조성물 |
| EP2653166A3 (en) * | 2007-07-30 | 2014-08-27 | Healor Ltd. | Pharmaceutical composition and related methods |
| GB0724231D0 (en) * | 2007-12-12 | 2008-01-30 | Renono Ltd | Methods for inhibiting scarring |
| CA2710375A1 (en) * | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Treatment of orthopedic conditions |
| EP2252690A2 (en) * | 2007-12-21 | 2010-11-24 | Coda Therapeutics, Inc. | Use of anti-connexin 43 polynucleotides for the treatment of abnormal or excessive scars |
| EP2234656A2 (en) | 2007-12-21 | 2010-10-06 | Coda Therapeutics, Inc. | Improved medical devices |
| MX2010010431A (es) * | 2008-03-25 | 2010-11-25 | Paloma Pharmaceuticals Inc | Metodos para tratar desordenes fibroticos. |
| CN102256625B (zh) | 2008-12-17 | 2013-11-20 | 默沙东公司 | 单和双peg il10的生产和用途 |
| ES2601827T3 (es) * | 2009-02-24 | 2017-02-16 | Arava Bio-Tech Ltd. | Agentes antagonistas de visfatina para el tratamiento del acné y de otras afecciones |
| WO2012112791A1 (en) | 2011-02-16 | 2012-08-23 | Paloma Pharmaceuticals, Inc. | Radiation countermeasure agents |
| US20140112898A1 (en) * | 2011-03-31 | 2014-04-24 | President And Fellows Of Harvard College | Unique population of regulatory t cells that regulate tissue regeneration and wound healing |
| CN104768567B (zh) * | 2012-05-18 | 2017-07-11 | 奥塔哥创业有限公司 | 用于伤口愈合的联合治疗和组合物 |
| JP2016519108A (ja) | 2013-04-18 | 2016-06-30 | アルモ・バイオサイエンシーズ・インコーポレイテッド | インターロイキン−10を疾病及び疾患の治療に用いる方法 |
| WO2014204816A2 (en) | 2013-06-17 | 2014-12-24 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
| US10098929B2 (en) | 2013-08-02 | 2018-10-16 | Children's Hospital Medical Center | Method of reducing scar formation in healing of dermal wounds by administering interleukin-10 and hyaluronan |
| CA2920679A1 (en) | 2013-08-30 | 2015-03-05 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| CN105848674A (zh) | 2013-11-11 | 2016-08-10 | 阿尔莫生物科技股份有限公司 | 将白细胞介素-10用于治疗疾病和病症的方法 |
| US10293043B2 (en) | 2014-06-02 | 2019-05-21 | Armo Biosciences, Inc. | Methods of lowering serum cholesterol |
| JP6683686B2 (ja) | 2014-08-22 | 2020-04-22 | オークランド ユニサービシーズ リミティド | チャネル調節剤 |
| CA2963989A1 (en) | 2014-10-14 | 2016-04-21 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
| CN107106655A (zh) | 2014-10-22 | 2017-08-29 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素‑10治疗疾病和病症的方法 |
| WO2016126615A1 (en) | 2015-02-03 | 2016-08-11 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
| CN107847583A (zh) | 2015-05-28 | 2018-03-27 | 阿尔莫生物科技股份有限公司 | 用于治疗癌症的聚乙二醇化白细胞介素‑10 |
| EP3341012B1 (en) | 2015-08-25 | 2025-07-30 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929442A (en) | 1986-09-26 | 1990-05-29 | Exovir, Inc. | Compositions suitable for human topical application including a growth factor and/or related materials |
| EP0280560B1 (en) | 1987-02-27 | 1994-05-11 | EASTMAN KODAK COMPANY (a New Jersey corporation) | Membrane structure coated with low pI protein and methods of making and using |
| EP0454736A4 (en) * | 1989-01-20 | 1993-05-12 | The University Of Melbourne | Fibrinolysis |
| US5242902A (en) | 1989-09-06 | 1993-09-07 | The Regents Of The University Of California | Defensin peptide compositions and methods for their use |
| AU635377B2 (en) * | 1989-11-21 | 1993-03-18 | University Of Melbourne, The | Anti-inflammatory compositions and methods |
| ATE171625T1 (de) | 1990-04-11 | 1998-10-15 | Brigham & Womens Hospital | Therapeutische verwendung von actin-bindenden verbindungen |
| ES2085003T3 (es) * | 1991-01-10 | 1996-05-16 | Schering Corp | Uso de il-4 para mejorar la fase reparadora de la curacion y restaño de heridas y para mejorar la curacion de heridas infectadas y las heridas de mamiferos diabeticos. |
| GB9106678D0 (en) | 1991-03-28 | 1991-05-15 | Ferguson Mark W J | Wound healing |
| AU8647991A (en) | 1991-08-26 | 1993-03-16 | State of Oregon Acting by and Through The State of Board of Higher Education on Behalf of The Oregon Health Sciences University, The | Keratinocyte-derived conditioned medium as a source of growth factors |
| GB9206861D0 (en) * | 1992-03-28 | 1992-05-13 | Univ Manchester | Wound healing and treatment of fibrotic disorders |
| GB9207732D0 (en) * | 1992-04-06 | 1992-05-27 | Isis Innovation | Wound repair |
| WO1994027640A1 (en) * | 1993-05-27 | 1994-12-08 | The Regents Of The University Of Michigan | Method of treatment and prevention of immune complex-induced lung injury |
| NZ269663A (en) | 1993-07-26 | 1997-09-22 | Schering Corp | Agonists and antagonists of il-10 |
| AU710153B2 (en) * | 1994-03-29 | 1999-09-16 | Renovo Limited | Wound healing |
| EP1621206A1 (en) * | 1994-12-12 | 2006-02-01 | Beth Israel Deaconess Medical Center, Inc. | Chimeric cytokines and uses thereof |
| GB9516012D0 (en) | 1995-08-04 | 1995-10-04 | Univ Manchester | Pharmaceutical composition |
| GB2304045A (en) | 1995-08-04 | 1997-03-12 | Univ Manchester | Betaglycan compositions for promoting the healing of wounds and fibrotic diseases |
-
1995
- 1995-08-09 GB GB9516287A patent/GB2304047A/en not_active Withdrawn
-
1996
- 1996-08-08 PT PT96926507T patent/PT871473E/pt unknown
- 1996-08-08 WO PCT/GB1996/001930 patent/WO1997005894A1/en not_active Ceased
- 1996-08-08 DE DE69625516T patent/DE69625516T2/de not_active Expired - Lifetime
- 1996-08-08 EP EP96926507A patent/EP0871473B1/en not_active Expired - Lifetime
- 1996-08-08 ES ES96926507T patent/ES2187665T3/es not_active Expired - Lifetime
- 1996-08-08 AU AU66660/96A patent/AU719089B2/en not_active Ceased
- 1996-08-08 DK DK96926507T patent/DK0871473T3/da active
- 1996-08-08 AT AT96926507T patent/ATE229814T1/de active
- 1996-08-08 JP JP50824697A patent/JP4050317B2/ja not_active Expired - Fee Related
- 1996-08-08 CA CA2229078A patent/CA2229078C/en not_active Expired - Fee Related
- 1996-08-08 ZA ZA9606744A patent/ZA966744B/xx unknown
- 1996-08-08 US US09/011,027 patent/US6387364B1/en not_active Expired - Lifetime
-
2002
- 2002-02-26 US US10/082,221 patent/US7052684B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6387364B1 (en) | 2002-05-14 |
| ZA966744B (en) | 1998-02-09 |
| JPH11510505A (ja) | 1999-09-14 |
| US20020128447A1 (en) | 2002-09-12 |
| AU6666096A (en) | 1997-03-05 |
| EP0871473B1 (en) | 2002-12-18 |
| DE69625516T2 (de) | 2003-09-25 |
| EP0871473A1 (en) | 1998-10-21 |
| DK0871473T3 (da) | 2003-04-14 |
| CA2229078C (en) | 2010-04-20 |
| ES2187665T3 (es) | 2003-06-16 |
| AU719089B2 (en) | 2000-05-04 |
| GB2304047A (en) | 1997-03-12 |
| GB9516287D0 (en) | 1995-10-11 |
| PT871473E (pt) | 2003-03-31 |
| CA2229078A1 (en) | 1997-02-20 |
| WO1997005894A1 (en) | 1997-02-20 |
| US7052684B2 (en) | 2006-05-30 |
| DE69625516D1 (de) | 2003-01-30 |
| ATE229814T1 (de) | 2003-01-15 |
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