ATE229814T1 - Verwendung von il-10 zur wundheilung mit verminderter narbenbildung - Google Patents

Verwendung von il-10 zur wundheilung mit verminderter narbenbildung

Info

Publication number
ATE229814T1
ATE229814T1 AT96926507T AT96926507T ATE229814T1 AT E229814 T1 ATE229814 T1 AT E229814T1 AT 96926507 T AT96926507 T AT 96926507T AT 96926507 T AT96926507 T AT 96926507T AT E229814 T1 ATE229814 T1 AT E229814T1
Authority
AT
Austria
Prior art keywords
wound healing
reduced
scaring
reduced scaring
healing
Prior art date
Application number
AT96926507T
Other languages
English (en)
Inventor
Mark William James Ba Ferguson
High Peak Vale
Original Assignee
Renovo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovo Ltd filed Critical Renovo Ltd
Application granted granted Critical
Publication of ATE229814T1 publication Critical patent/ATE229814T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2066—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Invalid Beds And Related Equipment (AREA)
  • Eye Examination Apparatus (AREA)
  • Prostheses (AREA)
AT96926507T 1995-08-09 1996-08-08 Verwendung von il-10 zur wundheilung mit verminderter narbenbildung ATE229814T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9516287A GB2304047A (en) 1995-08-09 1995-08-09 Pharmaceutical compositions containing cytokines
PCT/GB1996/001930 WO1997005894A1 (en) 1995-08-09 1996-08-08 Pharmaceutical composition containing il-10

Publications (1)

Publication Number Publication Date
ATE229814T1 true ATE229814T1 (de) 2003-01-15

Family

ID=10778967

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96926507T ATE229814T1 (de) 1995-08-09 1996-08-08 Verwendung von il-10 zur wundheilung mit verminderter narbenbildung

Country Status (13)

Country Link
US (2) US6387364B1 (de)
EP (1) EP0871473B1 (de)
JP (1) JP4050317B2 (de)
AT (1) ATE229814T1 (de)
AU (1) AU719089B2 (de)
CA (1) CA2229078C (de)
DE (1) DE69625516T2 (de)
DK (1) DK0871473T3 (de)
ES (1) ES2187665T3 (de)
GB (1) GB2304047A (de)
PT (1) PT871473E (de)
WO (1) WO1997005894A1 (de)
ZA (1) ZA966744B (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT941108E (pt) * 1996-12-04 2003-01-31 Renovo Ltd Cicatrizacao de feridas e tratamento da fibrose
AU6045198A (en) * 1997-02-05 1998-08-25 Schering Corporation Use of il-4 and/or il-10 to treat proliferative glomerulonephritis
EP1214090A2 (de) * 1999-09-08 2002-06-19 Schering Corporation Verwendungen von ccr6-säugetierenrezeptoren und und verwandte reagenzien
US20060258562A1 (en) * 2000-07-31 2006-11-16 Healor Ltd. Methods and pharmaceutical compositions for healing wounds
EP1324779B1 (de) 2000-09-29 2011-07-20 Schering Corporation Pegyliertes interleukin 10
AU2002365261A1 (en) * 2001-10-18 2003-09-02 The Children's Hospital Of Philadelphia Methods and materials for the recruitment of endothelial cells
NZ545318A (en) * 2003-07-15 2009-06-26 Univ Bar Ilan Pharmaceutical compositions for healing wounds comprising insulin and PKC alpha inhibitor
CA2535029C (en) 2003-08-07 2013-07-16 Healor Ltd. Pharmaceutical compositions and methods for accelerating wound healing
GB0500643D0 (en) 2005-01-13 2005-02-23 Renovo Ltd Medicaments
GB0524103D0 (en) 2005-11-26 2006-01-04 Medical Res Council Healing
AU2007314501B2 (en) 2006-09-28 2013-05-23 Merck Sharp & Dohme Corp. Use of pegylated IL-10 to treat cancer
CN101965193A (zh) 2006-11-15 2011-02-02 科达治疗公司 用于伤口愈合的改进方法和组合物
KR20130121678A (ko) * 2007-07-30 2013-11-06 힐로 리미티드 약제학적 조성물 및 관련 방법
GB0724231D0 (en) * 2007-12-12 2008-01-30 Renono Ltd Methods for inhibiting scarring
WO2009085269A2 (en) * 2007-12-21 2009-07-09 Coda Therapeutics, Inc. Use of anti-connexin polynucleotides, peptides or antibodies for the treatment of orthopedic conditions
AU2008343758A1 (en) * 2007-12-21 2009-07-09 Coda Therapeutics, Inc. Use of anti-connexin 43 polynucleotides for the treatment of abnormal or excessive scars
EP2234656A2 (de) 2007-12-21 2010-10-06 Coda Therapeutics, Inc. Verbesserte medizinische vorrichtungen
EP2271334B1 (de) * 2008-03-25 2015-08-12 Paloma Pharmaceuticals, Inc. Verfahren zur behandlung von fibrotischen erkrankungen
US8691205B2 (en) 2008-12-17 2014-04-08 Merck Sharp & Dohme Corporation Mono- and di-PEG IL-10 production; and uses
CN102325789A (zh) * 2009-02-24 2012-01-18 希尔洛有限公司 用于治疗痤疮和其它病症的内脂素治疗药物
WO2012112791A1 (en) 2011-02-16 2012-08-23 Paloma Pharmaceuticals, Inc. Radiation countermeasure agents
US20140112898A1 (en) * 2011-03-31 2014-04-24 President And Fellows Of Harvard College Unique population of regulatory t cells that regulate tissue regeneration and wound healing
EP2849774A4 (de) * 2012-05-18 2015-11-25 Otago Innovation Ltd Kombinationsbehandlungen und zusammensetzungen zur wundheilung
US9943568B2 (en) 2013-04-18 2018-04-17 Armo Biosciences, Inc. Methods of using pegylated interleukin-10 for treating cancer
ES2688206T3 (es) 2013-06-17 2018-10-31 Armo Biosciences, Inc. Procedimiento de evaluación de la identidad y la estabilidad de proteínas
US10098929B2 (en) 2013-08-02 2018-10-16 Children's Hospital Medical Center Method of reducing scar formation in healing of dermal wounds by administering interleukin-10 and hyaluronan
CN105658232A (zh) 2013-08-30 2016-06-08 阿尔莫生物科技股份有限公司 使用白细胞介素-10治疗疾病和病症的方法
WO2015070060A1 (en) 2013-11-11 2015-05-14 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10293043B2 (en) 2014-06-02 2019-05-21 Armo Biosciences, Inc. Methods of lowering serum cholesterol
EP3183346A4 (de) 2014-08-22 2018-10-24 Auckland Uniservices Limited Kanalmodulator
MX2017004838A (es) 2014-10-14 2017-10-16 Armo Biosciences Inc Composiciones de interleucina-15 y usos de estas.
AU2015336101A1 (en) 2014-10-22 2017-04-20 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10618970B2 (en) 2015-02-03 2020-04-14 Armo Biosciences, Inc. Method of treating cancer with IL-10 and antibodies that induce ADCC
EP3302547A1 (de) 2015-05-28 2018-04-11 Armo Biosciences, Inc. Pegyliertes interleukin-10 zur behandlung von krebs
EP3341012A4 (de) 2015-08-25 2019-03-20 Armo Biosciences, Inc. Verfahren zur verwendung von interleukin-10 zur behandlung von erkrankungen und leiden

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929442A (en) 1986-09-26 1990-05-29 Exovir, Inc. Compositions suitable for human topical application including a growth factor and/or related materials
EP0280560B1 (de) 1987-02-27 1994-05-11 EASTMAN KODAK COMPANY (a New Jersey corporation) Mit Nieder-pI-Protein beschichtete Membranstruktur und Verfahren zu ihrer Herstellung und Verwendung
JPH0611706B2 (ja) * 1989-01-20 1994-02-16 ザ ユニバーシティ オブ メルボルン フィブリン溶解
US5242902A (en) * 1989-09-06 1993-09-07 The Regents Of The University Of California Defensin peptide compositions and methods for their use
EP0502080A4 (en) * 1989-11-21 1993-02-10 The University Of Melbourne Anti-inflammatory compositions and methods
DK0526544T3 (da) 1990-04-11 1999-06-21 Brigham & Womens Hospital Terapeutiske anvendelser af actinbindende forbindelser
EP0566661B1 (de) * 1991-01-10 1996-03-13 Schering Corporation Verwendung von il-4 zur verstärkung von wundheilung und besserung und zur heilung von infizierten wunden und wunden bei diabetischen säugetieren
GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
WO1993004164A1 (en) 1991-08-26 1993-03-04 THE STATE OF OREGON acting by and through THE STATE OF BOARD OF HIGHER EDUCATION on behalf of THE OREGON HEALTH SCIENCES UNIVERSITY Keratinocyte-derived conditioned medium as a source of growth factors
GB9206861D0 (en) * 1992-03-28 1992-05-13 Univ Manchester Wound healing and treatment of fibrotic disorders
GB9207732D0 (en) * 1992-04-06 1992-05-27 Isis Innovation Wound repair
AU7043694A (en) * 1993-05-27 1994-12-20 Regents Of The University Of Michigan, The Method of treatment and prevention of immune complex-induced lung injury
ZA945434B (en) 1993-07-26 1995-01-23 Schering Corp Agonists and antagonists of human interleukin-10
NZ282856A (en) * 1994-03-29 1998-06-26 Univ Manchester Promoting wound healing using an agent (antibody) specific to a growth factor or associated protein
CA2205572A1 (en) * 1994-12-12 1996-06-20 Beth Israel Hospital Association Chimeric cytokines and uses thereof
GB9516012D0 (en) * 1995-08-04 1995-10-04 Univ Manchester Pharmaceutical composition
GB2304045A (en) * 1995-08-04 1997-03-12 Univ Manchester Betaglycan compositions for promoting the healing of wounds and fibrotic diseases

Also Published As

Publication number Publication date
EP0871473A1 (de) 1998-10-21
ZA966744B (en) 1998-02-09
DE69625516D1 (de) 2003-01-30
DK0871473T3 (da) 2003-04-14
DE69625516T2 (de) 2003-09-25
ES2187665T3 (es) 2003-06-16
US6387364B1 (en) 2002-05-14
CA2229078A1 (en) 1997-02-20
EP0871473B1 (de) 2002-12-18
AU719089B2 (en) 2000-05-04
CA2229078C (en) 2010-04-20
JPH11510505A (ja) 1999-09-14
US7052684B2 (en) 2006-05-30
PT871473E (pt) 2003-03-31
WO1997005894A1 (en) 1997-02-20
US20020128447A1 (en) 2002-09-12
GB2304047A (en) 1997-03-12
AU6666096A (en) 1997-03-05
JP4050317B2 (ja) 2008-02-20
GB9516287D0 (en) 1995-10-11

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