JP3944393B2 - インスリン抵抗性および糖尿病のための、コリン塩基とコハク酸とを含む相乗効果のある組成物 - Google Patents

インスリン抵抗性および糖尿病のための、コリン塩基とコハク酸とを含む相乗効果のある組成物 Download PDF

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Publication number
JP3944393B2
JP3944393B2 JP2001574101A JP2001574101A JP3944393B2 JP 3944393 B2 JP3944393 B2 JP 3944393B2 JP 2001574101 A JP2001574101 A JP 2001574101A JP 2001574101 A JP2001574101 A JP 2001574101A JP 3944393 B2 JP3944393 B2 JP 3944393B2
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Japan
Prior art keywords
succinic acid
pharmaceutically acceptable
insulin resistance
acceptable salt
insulin
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2001574101A
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English (en)
Japanese (ja)
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JP2004506605A (ja
JP2004506605A5 (cg-RX-API-DMAC7.html
Inventor
イゴール・アナトリエヴィッチ・ポミトキン
オルガ・エフゲニエフナ・コレソヴァ
タチアナ・ユリエフナ・ウクハノヴァ
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Publication of JP2004506605A publication Critical patent/JP2004506605A/ja
Publication of JP2004506605A5 publication Critical patent/JP2004506605A5/ja
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Publication of JP3944393B2 publication Critical patent/JP3944393B2/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2001574101A 2000-04-10 2000-04-10 インスリン抵抗性および糖尿病のための、コリン塩基とコハク酸とを含む相乗効果のある組成物 Expired - Fee Related JP3944393B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2000/000122 WO2001076583A1 (en) 2000-04-10 2000-04-10 Synergistic compositions containing choline base and succinic acid for insulin resistance and diabetes

Publications (3)

Publication Number Publication Date
JP2004506605A JP2004506605A (ja) 2004-03-04
JP2004506605A5 JP2004506605A5 (cg-RX-API-DMAC7.html) 2005-02-03
JP3944393B2 true JP3944393B2 (ja) 2007-07-11

Family

ID=20129496

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001574101A Expired - Fee Related JP3944393B2 (ja) 2000-04-10 2000-04-10 インスリン抵抗性および糖尿病のための、コリン塩基とコハク酸とを含む相乗効果のある組成物

Country Status (8)

Country Link
EP (1) EP1272171A1 (cg-RX-API-DMAC7.html)
JP (1) JP3944393B2 (cg-RX-API-DMAC7.html)
KR (1) KR20020089444A (cg-RX-API-DMAC7.html)
CN (1) CN1452482A (cg-RX-API-DMAC7.html)
AU (1) AU2000263274A1 (cg-RX-API-DMAC7.html)
BR (1) BR0017206A (cg-RX-API-DMAC7.html)
CA (1) CA2404864A1 (cg-RX-API-DMAC7.html)
WO (1) WO2001076583A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163212A2 (en) 2024-08-09 2025-08-07 Jantar Gmbh Succinic acid or a pharmaceutically acceptable salt thereof for use in the treatment of chronic rhinosinusitis

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004112773A1 (en) * 2003-04-24 2004-12-29 Shin-Jen Shiao Pharmaceutical compositions used for immune disease treatment and improvement
KR20100031760A (ko) * 2007-08-02 2010-03-24 부다 바이오파마 오와이 리미티드 숙신산의 콜린염을 포함하는 비강내 투여용 약학 조성물
KR101360569B1 (ko) 2008-11-26 2014-02-10 이고르 아나토리에비치 포밋트킨 우울증, 불안증, 정신분열증, 수면장애 및 간질의 치료를 위한 숙신산의 콜린염
US8314080B2 (en) 2010-04-06 2012-11-20 Kuwait University Method of treating type I diabetes
CN106727476A (zh) * 2016-12-09 2017-05-31 杨远志 一种组合物及其在改善动物肌纤维类型中的应用
CN121152781A (zh) 2023-05-05 2025-12-16 米拓克兰有限公司 合成方法
WO2025120626A2 (en) 2025-04-14 2025-06-12 Mitocholine Ltd Synthetic method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6346669D0 (pt) * 1962-02-12 1973-06-14 Squibb & Sons Inc Processo de preparacao de uma composicao farmaceutica estavel de sais de esteres de colina
JPS61171417A (ja) * 1985-01-23 1986-08-02 Wakunaga Seiyaku Kk 抗糖尿病剤
US6294520B1 (en) * 1989-03-27 2001-09-25 Albert T. Naito Material for passage through the blood-brain barrier
JPH03169498A (ja) * 1989-11-28 1991-07-23 Yotsukaichi Gosei Kk 水溶性はんだフラックス
JPH0586319A (ja) * 1991-09-27 1993-04-06 Pentel Kk 水性インキ組成物
US5895652A (en) * 1996-07-29 1999-04-20 Longevity Institute International Method of metabolic adjuvanation and cellular repair
PT1156795E (pt) * 1999-03-01 2004-09-30 Pavel Vasilievich Verteletsky Utilizacao de acido succinico ou de seus sais e metodo de tratamento da resistencia a insulina
AU4937699A (en) * 1999-04-05 2000-10-23 Olga Evgenievna Kolesova Use of succinic acid or salts thereof for the treatment of diabetes mellitus andwound healing

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163212A2 (en) 2024-08-09 2025-08-07 Jantar Gmbh Succinic acid or a pharmaceutically acceptable salt thereof for use in the treatment of chronic rhinosinusitis

Also Published As

Publication number Publication date
KR20020089444A (ko) 2002-11-29
BR0017206A (pt) 2003-01-14
CN1452482A (zh) 2003-10-29
CA2404864A1 (en) 2001-10-18
EP1272171A1 (en) 2003-01-08
AU2000263274A1 (en) 2001-10-23
JP2004506605A (ja) 2004-03-04
WO2001076583A1 (en) 2001-10-18

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