JP3860838B2 - 抗微生物性陽イオン性ペプチドおよびそのスクリーニング方法 - Google Patents
抗微生物性陽イオン性ペプチドおよびそのスクリーニング方法 Download PDFInfo
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Classifications
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- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US268795P | 1995-08-23 | 1995-08-23 | |
| US60/002,687 | 1995-08-23 | ||
| PCT/IB1996/000996 WO1997008199A2 (en) | 1995-08-23 | 1996-08-23 | Antimicrobial cationic peptides and methods of screening for the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH11511971A JPH11511971A (ja) | 1999-10-19 |
| JPH11511971A5 JPH11511971A5 (enExample) | 2004-08-12 |
| JP3860838B2 true JP3860838B2 (ja) | 2006-12-20 |
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| US (2) | US6191254B1 (enExample) |
| EP (1) | EP0846128B1 (enExample) |
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| AU (1) | AU6940796A (enExample) |
| CA (1) | CA2230160A1 (enExample) |
| DE (1) | DE69637731D1 (enExample) |
| ES (1) | ES2316154T3 (enExample) |
| WO (1) | WO1997008199A2 (enExample) |
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| US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
| EP1174439B1 (en) * | 1996-08-21 | 2008-10-08 | Migenix Inc. | Compositions and methods for treating infections using analogues of indolicidin |
| US6180604B1 (en) * | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
| US6303575B1 (en) | 1998-05-12 | 2001-10-16 | The Regents Of The University Of California | Indolicidin analogs and methods of using same |
| US6444645B1 (en) | 1998-06-18 | 2002-09-03 | The Regents Of The University Of California | Crosslink-stabilized indolicidin analogs |
| US6288212B1 (en) * | 1998-08-28 | 2001-09-11 | The University Of British Columbia | Anti-endotoxic, antimicrobial cationic peptides and methods of use therefor |
| WO2000026344A1 (en) * | 1998-10-30 | 2000-05-11 | Interlink Biotechnologies Llc | Peptides with enhanced stability to protease degradation |
| US6946261B1 (en) | 1998-11-20 | 2005-09-20 | Migenix Inc. | Efficient methods for producing anti-microbial cationic peptides in host cells |
| US6335318B1 (en) | 1999-05-10 | 2002-01-01 | The Regents Of The University Of California | Antimicrobial theta defensins and methods of using same |
| US6497676B1 (en) | 2000-02-10 | 2002-12-24 | Baxter International | Method and apparatus for monitoring and controlling peritoneal dialysis therapy |
| US6337317B1 (en) * | 2000-06-27 | 2002-01-08 | The University Of British Columbia | Antimicrobial peptides and methods of use thereof |
| US6835536B2 (en) | 2001-08-21 | 2004-12-28 | Micrologix Biotech Inc. | Antimicrobial cationic peptides and formulations thereof |
| JP4511173B2 (ja) | 2001-08-24 | 2010-07-28 | マイジェニックス インコーポレイテッド | 抗菌性および抗炎症性ペプチド |
| KR100438416B1 (ko) * | 2001-09-19 | 2004-07-02 | 학교법인조선대학교 | Ca-ma 펩타이드의 아미노산 중 하나 또는 그 이상을치환하여 + 전극과 소수성 영역이 증가된 신규한펩타이드 및 그를 포함하는 약학적 조성물 |
| US7507787B2 (en) * | 2001-12-03 | 2009-03-24 | The University Of British Columbia | Effectors of innate immunity |
| US20030125662A1 (en) * | 2002-01-03 | 2003-07-03 | Tuan Bui | Method and apparatus for providing medical treatment therapy based on calculated demand |
| US20030219854A1 (en) * | 2002-03-21 | 2003-11-27 | Micrologix Biotech Inc. | Methods for producing modified anti-infective peptides |
| DE60335101D1 (de) * | 2002-04-25 | 2011-01-05 | Toagosei Co Ltd | Antimikrobielles polypeptid und nutzung davon |
| US7119070B2 (en) | 2002-04-30 | 2006-10-10 | The Regents Of The University Of California | Antimicrobial theta defensins, analogs thereof, and methods of use |
| US7033769B2 (en) * | 2002-05-23 | 2006-04-25 | The United States Of America As Represented By The Secretary Of The Army | Method for discovering one or more peptides adapted for specific binding to a microorganism of interest |
| US7238164B2 (en) | 2002-07-19 | 2007-07-03 | Baxter International Inc. | Systems, methods and apparatuses for pumping cassette-based therapies |
| WO2005019241A2 (en) * | 2003-08-18 | 2005-03-03 | E.I. Dupont De Nemours And Company | Cationic antimicrobial peptides and compositions thereof |
| JP4524671B2 (ja) * | 2003-10-29 | 2010-08-18 | 東亞合成株式会社 | 抗菌ペプチド及びその利用 |
| US20050209563A1 (en) * | 2004-03-19 | 2005-09-22 | Peter Hopping | Cassette-based dialysis medical fluid therapy systems, apparatuses and methods |
| JP4507080B2 (ja) * | 2004-07-30 | 2010-07-21 | 東亞合成株式会社 | 抗菌ペプチド及びその利用 |
| JP4730584B2 (ja) | 2004-12-06 | 2011-07-20 | 東亞合成株式会社 | 抗菌ペプチド及びその利用 |
| EP1838331A4 (en) | 2004-12-15 | 2012-12-26 | Univ Colorado | ANTIMICROBIAL PEPTIDES AND METHOD OF USE |
| WO2006088010A1 (ja) * | 2005-02-15 | 2006-08-24 | Toagosei Co., Ltd. | 抗菌ペプチド及びその利用 |
| US8870812B2 (en) | 2007-02-15 | 2014-10-28 | Baxter International Inc. | Dialysis system having video display with ambient light adjustment |
| US8558964B2 (en) | 2007-02-15 | 2013-10-15 | Baxter International Inc. | Dialysis system having display with electromagnetic compliance (“EMC”) seal |
| US7998115B2 (en) * | 2007-02-15 | 2011-08-16 | Baxter International Inc. | Dialysis system having optical flowrate detection |
| US7731689B2 (en) | 2007-02-15 | 2010-06-08 | Baxter International Inc. | Dialysis system having inductive heating |
| US8361023B2 (en) * | 2007-02-15 | 2013-01-29 | Baxter International Inc. | Dialysis system with efficient battery back-up |
| PL2178549T3 (pl) * | 2007-07-26 | 2017-03-31 | Revance Therapeutics, Inc. | Peptyd przeciwdrobnoustrojowy i jego kompozycje |
| US20100099614A1 (en) * | 2008-10-06 | 2010-04-22 | Hodges Robert S | Antimicrobial Peptides and Methods of Use |
| GB0821616D0 (en) * | 2008-11-26 | 2008-12-31 | Lytix Biopharma As | Compounds |
| EP2437770A4 (en) * | 2009-06-05 | 2013-11-06 | Univ Colorado Regents | ANTIMICROBIAL PEPTIDES |
| US9134323B2 (en) | 2009-12-01 | 2015-09-15 | The Rockefeller University | Antibody that specifically binds to an epitope in the tureet region of a human Kir channel |
| EP2558577B1 (en) | 2010-04-16 | 2018-12-12 | Nuevolution A/S | Bi-functional complexes and methods for making and using such complexes |
| EP2755693A4 (en) | 2011-09-12 | 2015-05-20 | Moderna Therapeutics Inc | MANIPULATED NUCLEIC ACIDS AND METHOD OF APPLICATION THEREFOR |
| AU2013243954A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| AU2013243949A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of biologics and proteins associated with human disease |
| US20150072922A1 (en) * | 2012-04-17 | 2015-03-12 | The Research Institute At Nationwide Children's Hospital | Rnase 7 antimicrobial peptides |
| MY151307A (en) * | 2012-06-18 | 2014-05-05 | Univ Malaya | Peptides having antimicrobial activity |
| GB201401877D0 (en) | 2014-02-04 | 2014-03-19 | Univ Tromsoe | Peptides |
| EP3067608A1 (en) * | 2015-03-10 | 2016-09-14 | Abu Dhabi Polymers Co. Ltd (Borouge) LLC. | Eccentric polyolefin pipe |
| ES2981535T3 (es) | 2015-11-10 | 2024-10-09 | Visterra Inc | Conjugados de molécula de anticuerpo-fármaco que se unen específicamente al lipopolisacárido y usos de los mismos |
| CN110431150A (zh) | 2017-01-18 | 2019-11-08 | 威特拉公司 | 抗体分子-药物偶联物及其用途 |
| WO2018160791A1 (en) | 2017-03-03 | 2018-09-07 | Massachusetts Institute Of Technology | Antimicrobial constructs and uses thereof |
| US10934943B2 (en) | 2017-04-27 | 2021-03-02 | General Electric Company | Compressor apparatus with bleed slot and supplemental flange |
| US11179516B2 (en) | 2017-06-22 | 2021-11-23 | Baxter International Inc. | Systems and methods for incorporating patient pressure into medical fluid delivery |
| CA3178465A1 (en) | 2020-04-03 | 2021-10-07 | Visterra, Inc. | Antibody molecule-drug conjugates and uses thereof |
| CU24750B1 (es) * | 2020-11-19 | 2025-06-11 | Centro De Investig Y Desarrollo De Medicamentos Cidem | Entidades peptídicas con actividad antimicrobiana frente a patógenos multi-drogoresistentes |
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| US5028530A (en) | 1985-01-28 | 1991-07-02 | Xoma Corporation | AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques |
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| US5206154A (en) | 1985-01-28 | 1993-04-27 | Xoma Corporation | Method of producing cecropins by microbiological techniques |
| US4810777A (en) | 1987-03-04 | 1989-03-07 | The United States Of America As Represented By The Department Of Health And Human Services | Antimicrobial compounds |
| US4822608A (en) | 1987-09-14 | 1989-04-18 | Vespa Laboratories, Inc. | Methods and compositions for the treatment of mammalian infections employing medicaments comprising hymenoptera venom or proteinaceous or polypeptide components thereof |
| WO1989011290A1 (en) | 1988-05-27 | 1989-11-30 | Magainin Sciences, Inc. | Amphiphilic peptides and use thereof |
| SE8802939D0 (sv) | 1988-08-19 | 1988-08-19 | Kabigen Ab | A method for the production and isolation of a fusion protein in eukaryotic cells |
| US5217956A (en) | 1988-10-21 | 1993-06-08 | The Children's Hospital Of Philadelphia | Composition and treatment with biologically active peptides and certain anions |
| DE68916261T2 (de) | 1988-10-21 | 1994-09-22 | Philadelphia Children Hospital | Zusammensetzung und behandelung mittels biologisch aktiven peptiden und bestimmten anionen. |
| JPH04502901A (ja) | 1988-10-21 | 1992-05-28 | マゲイニン サイエンセス インコーポレーテッド | シーピーエフペプチド組成物およびその用途 |
| CA2007913A1 (en) | 1989-01-30 | 1990-07-30 | Michael Zasloff | Composition and treatment with peptide combinations |
| US5254535A (en) | 1989-04-17 | 1993-10-19 | The Children's Hospital Of Pennsylvania | Composition and treatment with biologically active peptides and antibiotic |
| FR2646777B1 (fr) | 1989-05-12 | 1993-09-03 | Bio Serae Lab | Procede de preparation d'un produit particulaire antimicrobien, produit antimicrobien obtenu et applications |
| US5073542A (en) | 1989-06-07 | 1991-12-17 | Magainin Sciences Inc. | CPF peptide compositions and their use in inhibiting growth of target cells or a virus |
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| WO1991016066A1 (en) | 1990-04-23 | 1991-10-31 | Magainin Sciences Inc. | Composition and treatment with biologically active peptides and toxic cations |
| JPH05507077A (ja) | 1990-04-27 | 1993-10-14 | マゲイニン サイエンセズ インコーポレーテッド | 生物活性ペプチドおよび駆虫剤もしくは抗真菌剤を使う組成物および治療法 |
| EP0533795A4 (en) | 1990-05-14 | 1993-10-20 | Magainin Sciences, Inc. | Composition of and treatment with biologically active peptides having d-amino acid residues |
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| EP0590044A4 (en) | 1991-06-12 | 1996-06-12 | Magainin Pharma | Composition and treatment with biologically active peptides having c-terminal substitutions |
| AU667479B2 (en) | 1991-06-12 | 1996-03-28 | Magainin Pharmaceuticals, Inc. | Treating the oral cavity with ion-channel forming peptides |
| US5547939A (en) | 1991-06-14 | 1996-08-20 | The Regents Of The University Of California | Broad spectrum antimicrobial compounds and methods of use |
| US5324716A (en) | 1991-06-14 | 1994-06-28 | Regents Of The University Of California | Broad spectrum antimicrobial compounds and methods of use |
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-
1996
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- 1996-08-23 DE DE69637731T patent/DE69637731D1/de not_active Expired - Lifetime
- 1996-08-23 CA CA002230160A patent/CA2230160A1/en not_active Abandoned
- 1996-08-23 US US08/702,054 patent/US6191254B1/en not_active Expired - Fee Related
- 1996-08-23 AU AU69407/96A patent/AU6940796A/en not_active Abandoned
- 1996-08-23 AT AT96930303T patent/ATE412668T1/de not_active IP Right Cessation
- 1996-08-23 EP EP96930303A patent/EP0846128B1/en not_active Expired - Lifetime
- 1996-08-23 JP JP51006897A patent/JP3860838B2/ja not_active Expired - Fee Related
- 1996-08-23 ES ES96930303T patent/ES2316154T3/es not_active Expired - Lifetime
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2003
- 2003-03-28 US US10/403,104 patent/US7390873B2/en not_active Expired - Fee Related
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|---|---|
| US7390873B2 (en) | 2008-06-24 |
| EP0846128B1 (en) | 2008-10-29 |
| US6191254B1 (en) | 2001-02-20 |
| EP0846128A2 (en) | 1998-06-10 |
| US20040019181A1 (en) | 2004-01-29 |
| WO1997008199A2 (en) | 1997-03-06 |
| AU6940796A (en) | 1997-03-19 |
| WO1997008199A3 (en) | 1997-09-12 |
| ES2316154T3 (es) | 2009-04-01 |
| CA2230160A1 (en) | 1997-03-06 |
| ATE412668T1 (de) | 2008-11-15 |
| DE69637731D1 (de) | 2008-12-11 |
| JPH11511971A (ja) | 1999-10-19 |
| HK1011867A1 (en) | 1999-07-23 |
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