JP3803318B2 - 遺伝子発現阻害方法 - Google Patents

遺伝子発現阻害方法 Download PDF

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Publication number
JP3803318B2
JP3803318B2 JP2002337903A JP2002337903A JP3803318B2 JP 3803318 B2 JP3803318 B2 JP 3803318B2 JP 2002337903 A JP2002337903 A JP 2002337903A JP 2002337903 A JP2002337903 A JP 2002337903A JP 3803318 B2 JP3803318 B2 JP 3803318B2
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double
rna
dna
stranded polynucleotide
gene
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Japanese (ja)
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JP2003219893A5 (enExample
JP2003219893A (ja
Inventor
久美子 程
隆英 梶
龍 上田
薫 西郷
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KABUSHIKIKAISHA RNAI
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KABUSHIKIKAISHA RNAI
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Publication of JP2003219893A5 publication Critical patent/JP2003219893A5/ja
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2002337903A 2001-11-21 2002-11-21 遺伝子発現阻害方法 Expired - Lifetime JP3803318B2 (ja)

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JP2002337903A JP3803318B2 (ja) 2001-11-21 2002-11-21 遺伝子発現阻害方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001-355896 2001-11-21
JP2001355896 2001-11-21
JP2002337903A JP3803318B2 (ja) 2001-11-21 2002-11-21 遺伝子発現阻害方法

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JP2003219893A JP2003219893A (ja) 2003-08-05
JP2003219893A5 JP2003219893A5 (enExample) 2006-03-02
JP3803318B2 true JP3803318B2 (ja) 2006-08-02

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008139938A1 (ja) * 2007-05-02 2008-11-20 National University Corporation Tokyo Medical And Dental University ヒトパピローマウイルス１６型遺伝子を標的とする二本鎖核酸分子及びそれを含む医薬
WO2008156172A1 (ja) * 2007-06-20 2008-12-24 Saitama Medical University 子宮癌、乳癌、及び膀胱癌の予防乃至治療に好適な二本鎖核酸分子、癌細胞増殖抑制剤、並びに医薬
JP2018537104A (ja) * 2015-12-13 2018-12-20 日東電工株式会社 高活性及びオフターゲット削減のためのｓｉＲＮＡ構造

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JP4843778B2 (ja) * 2003-10-08 2011-12-21 独立行政法人産業技術総合研究所 ｓｉＲＮＡのＲＮＡｉ効果算出装置
JP2009221164A (ja) 2008-03-17 2009-10-01 Nitto Denko Corp 肺線維症処置剤
DK2727583T3 (da) 2004-12-22 2021-12-20 Nitto Denko Corp Lægemiddelbærer og lægemiddelbærerkit til at inhibere fibrose
US20120269886A1 (en) 2004-12-22 2012-10-25 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
TWI407971B (zh) 2007-03-30 2013-09-11 Nitto Denko Corp Cancer cells and tumor-related fibroblasts
WO2009028418A1 (ja) 2007-08-24 2009-03-05 Sapporo Medical University シクロスポリンａ結合タンパク質
TWI455944B (zh) 2008-07-01 2014-10-11 Daiichi Sankyo Co Ltd 雙股多核苷酸
JP5950428B2 (ja) 2010-08-05 2016-07-13 日東電工株式会社 線維化組織から正常組織を再生するための組成物
EP2724729B1 (en) 2011-06-21 2018-12-26 Nitto Denko Corporation Apoptosis-inducing agent
JP6002382B2 (ja) * 2011-12-07 2016-10-05 株式会社バイオシンクタンク 遺伝子発現阻害剤及び阻害方法
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
JP6076076B2 (ja) 2012-12-21 2017-02-08 日東電工株式会社 組織再生促進剤
ES2821966T3 (es) 2014-04-02 2021-04-28 Nitto Denko Corp Molécula de direccionamiento derivada de RBP y utilización de la misma
RU2676680C2 (ru) 2014-04-07 2019-01-10 Нитто Денко Корпорейшн Новые гидротропы на основе полимера для доставки гидрофобного лекарственного средства
JP6727765B2 (ja) 2014-06-17 2020-07-22 日東電工株式会社 アポトーシス誘導剤

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008139938A1 (ja) * 2007-05-02 2008-11-20 National University Corporation Tokyo Medical And Dental University ヒトパピローマウイルス１６型遺伝子を標的とする二本鎖核酸分子及びそれを含む医薬
WO2008156172A1 (ja) * 2007-06-20 2008-12-24 Saitama Medical University 子宮癌、乳癌、及び膀胱癌の予防乃至治療に好適な二本鎖核酸分子、癌細胞増殖抑制剤、並びに医薬
US8124754B2 (en) 2007-06-20 2012-02-28 Saitama Medical University Double-stranded nucleic acid molecule cancer cell proliferation inhibitor and pharmaceutical agent suitable for prevention or treatment of uterine cancer, breast cancer, and bladder cancer
JP2018537104A (ja) * 2015-12-13 2018-12-20 日東電工株式会社 高活性及びオフターゲット削減のためのｓｉＲＮＡ構造
US10358647B2 (en) 2015-12-13 2019-07-23 Nitto Denko Corporation siRNA structures for high activity and reduced off target
US11390871B2 (en) 2015-12-13 2022-07-19 Nitto Denko Corporation SiRNA structures for high activity and reduced off target
US11926831B2 (en) 2015-12-13 2024-03-12 Nitto Denko Corporation SiRNA structures for high activity and reduced off target

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