JP2003219893A5 - - Google Patents

Download PDF

Info

Publication number
JP2003219893A5
JP2003219893A5 JP2002337903A JP2002337903A JP2003219893A5 JP 2003219893 A5 JP2003219893 A5 JP 2003219893A5 JP 2002337903 A JP2002337903 A JP 2002337903A JP 2002337903 A JP2002337903 A JP 2002337903A JP 2003219893 A5 JP2003219893 A5 JP 2003219893A5
Authority
JP
Japan
Prior art keywords
double
stranded polynucleotide
rna
dna
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002337903A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003219893A (ja
JP3803318B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority to JP2002337903A priority Critical patent/JP3803318B2/ja
Priority claimed from JP2002337903A external-priority patent/JP3803318B2/ja
Publication of JP2003219893A publication Critical patent/JP2003219893A/ja
Publication of JP2003219893A5 publication Critical patent/JP2003219893A5/ja
Application granted granted Critical
Publication of JP3803318B2 publication Critical patent/JP3803318B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2002337903A 2001-11-21 2002-11-21 遺伝子発現阻害方法 Expired - Lifetime JP3803318B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2002337903A JP3803318B2 (ja) 2001-11-21 2002-11-21 遺伝子発現阻害方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001-355896 2001-11-21
JP2001355896 2001-11-21
JP2002337903A JP3803318B2 (ja) 2001-11-21 2002-11-21 遺伝子発現阻害方法

Publications (3)

Publication Number Publication Date
JP2003219893A JP2003219893A (ja) 2003-08-05
JP2003219893A5 true JP2003219893A5 (enExample) 2006-03-02
JP3803318B2 JP3803318B2 (ja) 2006-08-02

Family

ID=27759143

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002337903A Expired - Lifetime JP3803318B2 (ja) 2001-11-21 2002-11-21 遺伝子発現阻害方法

Country Status (1)

Country Link
JP (1) JP3803318B2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4843778B2 (ja) * 2003-10-08 2011-12-21 独立行政法人産業技術総合研究所 siRNAのRNAi効果算出装置
US20120269886A1 (en) 2004-12-22 2012-10-25 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
SI2730277T1 (sl) 2004-12-22 2020-07-31 Nitto Denko Corporation Nosilec zdravila in komplet za nosilec zdravila za zaviranje fibroze
JP2009221164A (ja) 2008-03-17 2009-10-01 Nitto Denko Corp 肺線維症処置剤
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
TWI407971B (zh) 2007-03-30 2013-09-11 Nitto Denko Corp Cancer cells and tumor-related fibroblasts
WO2008139938A1 (ja) * 2007-05-02 2008-11-20 National University Corporation Tokyo Medical And Dental University ヒトパピローマウイルス16型遺伝子を標的とする二本鎖核酸分子及びそれを含む医薬
WO2008156172A1 (ja) * 2007-06-20 2008-12-24 Saitama Medical University 子宮癌、乳癌、及び膀胱癌の予防乃至治療に好適な二本鎖核酸分子、癌細胞増殖抑制剤、並びに医薬
US20110158908A1 (en) 2007-08-24 2011-06-30 Sapporo Medical University Cyclosporin a-binding protein
TWI455944B (zh) 2008-07-01 2014-10-11 Daiichi Sankyo Co Ltd 雙股多核苷酸
JP5950428B2 (ja) 2010-08-05 2016-07-13 日東電工株式会社 線維化組織から正常組織を再生するための組成物
JP6023709B2 (ja) 2011-06-21 2016-11-09 日東電工株式会社 アポトーシス誘導剤
JP6002382B2 (ja) * 2011-12-07 2016-10-05 株式会社バイオシンクタンク 遺伝子発現阻害剤及び阻害方法
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
JP6076076B2 (ja) 2012-12-21 2017-02-08 日東電工株式会社 組織再生促進剤
JP6602034B2 (ja) 2014-04-02 2019-11-06 日東電工株式会社 標的化分子およびその使用
WO2015155810A1 (en) 2014-04-07 2015-10-15 Nitto Denko Corporation Novel polymer-based hydrotropes for hydrophobic drug delivery
CN106573062B (zh) 2014-06-17 2020-08-25 日东电工株式会社 细胞凋亡诱导剂
KR102740699B1 (ko) 2015-12-13 2024-12-09 닛토덴코 가부시키가이샤 높은 활성 및 감소한 오프 타겟을 위한 sirna 구조

Similar Documents

Publication Publication Date Title
JP2003219893A5 (enExample)
JP2003520811A5 (enExample)
IL166546A (en) Double-stranded ribonucleic acid, preparations containing it, is used in drug preparation and in vitro method to inhibit the expression of a target gene
WO2004042029A3 (en) Oligomers comprising modified bases for binding cytosine and uracil or thymine and their use
WO2003051901A3 (en) Pseudonucleotide comprising an intercalator
WO2005014782A3 (en) Double-stranded ribonucleic acid with increased effectiveness in an organism
WO2003012052A3 (en) Specific inhibition of gene expression by small double stranded rnas
ZA200304500B (en) Method for inhibiting the expression of a target gene and medicament for treating a tumor disease.
EP2631292A3 (en) Human microRNAs and methods for inhibiting same
CA2565103C (en) Peptide conjugated, inosine-substituted antisense oligomer compound and method
WO2002026967A3 (en) Targeted gene correction by single-stranded oligodeoxynucleotides
JP2015142558A5 (enExample)
ATE328075T1 (de) Verfahren zur hemmung der expression eine zielgens
WO2003064625A3 (en) Oligonucleotide compositions with enhanced efficiency
EP1544297A3 (en) Medicament for treatment of Duchenne muscular dystrophy
JP2009524419A5 (enExample)
DE69838449D1 (de) Aminooxy-modifizierte oligonukleotide
JP2006526394A5 (enExample)
DE69934227D1 (de) Auf beta-arabinose, und dessen analogen, basierte antisense oligonukleotide
WO2007031319A8 (en) Compositions comprising immunostimulatory rna oligonucleotides and methods for producing said rna oligonucleotides
EP2062586A3 (en) Use of low doses of oligonucleotides antisense to tgf-beta, vegf, interleukin-10, c-jun, c-fos or prostaglandin e2 genes in the treatment of tumors
WO2004078941A3 (en) Modulation of gene expression using dna-rna hybrids
WO2004044134A3 (en) Phosphorous-linked oligomeric compounds and their use in gene modulation
EP3040423A3 (en) Microrna and uses thereof
JP2006523103A5 (enExample)