JP3223321B2 - エレクトロポレーション及びイオントフォレシス装置、並びに細胞への薬剤及び遺伝子の注入方法 - Google Patents

エレクトロポレーション及びイオントフォレシス装置、並びに細胞への薬剤及び遺伝子の注入方法

Info

Publication number
JP3223321B2
JP3223321B2 JP51967595A JP51967595A JP3223321B2 JP 3223321 B2 JP3223321 B2 JP 3223321B2 JP 51967595 A JP51967595 A JP 51967595A JP 51967595 A JP51967595 A JP 51967595A JP 3223321 B2 JP3223321 B2 JP 3223321B2
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JP
Japan
Prior art keywords
blood vessel
electric field
cells
predetermined
electrodes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP51967595A
Other languages
English (en)
Japanese (ja)
Other versions
JPH09511385A (ja
Inventor
ガンター エイ． ホフマン，
ロイス ジェイ． クランデル，
Original Assignee
ジェネトロニクス， インク．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジェネトロニクス， インク． filed Critical ジェネトロニクス， インク．
Publication of JPH09511385A publication Critical patent/JPH09511385A/ja
Application granted granted Critical
Publication of JP3223321B2 publication Critical patent/JP3223321B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00—Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02—Dilators made of swellable material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP51967595A 1994-01-21 1995-01-20 エレクトロポレーション及びイオントフォレシス装置、並びに細胞への薬剤及び遺伝子の注入方法 Expired - Fee Related JP3223321B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US183,963 1994-01-21
US08/183,963 US5507724A (en) 1992-07-01 1994-01-21 Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells
US08/183,963 1994-01-21
PCT/US1995/000799 WO1995019805A1 (fr) 1994-01-21 1995-01-20 Appareil d'electroporation et d'ionophorese et procede d'insertion de medicaments et de genes dans les cellules

Publications (2)

Publication Number Publication Date
JPH09511385A JPH09511385A (ja) 1997-11-18
JP3223321B2 true JP3223321B2 (ja) 2001-10-29

Family

ID=22675037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51967595A Expired - Fee Related JP3223321B2 (ja) 1994-01-21 1995-01-20 エレクトロポレーション及びイオントフォレシス装置、並びに細胞への薬剤及び遺伝子の注入方法

Country Status (11)

Country Link
US (1) US5507724A (fr)
EP (1) EP0740564B1 (fr)
JP (1) JP3223321B2 (fr)
AT (1) ATE236681T1 (fr)
AU (1) AU1605295A (fr)
CA (1) CA2177655C (fr)
DE (1) DE69530283T2 (fr)
DK (1) DK0740564T3 (fr)
ES (1) ES2196057T3 (fr)
PT (1) PT740564E (fr)
WO (1) WO1995019805A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6999654B2 (ja) 2016-09-26 2022-01-18 ヴェリリー ライフ サイエンシズ エルエルシー 遠近調節コンタクトレンズのための鋳造－成型可能な、高屈折率、剛性、ガス透過性ポリマ配合物

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ATE236681T1 (de) 2003-04-15
CA2177655C (fr) 2001-09-25
DK0740564T3 (da) 2003-07-28
DE69530283T2 (de) 2004-01-29
AU1605295A (en) 1995-08-08
US5507724A (en) 1996-04-16
EP0740564A1 (fr) 1996-11-06
CA2177655A1 (fr) 1995-07-27
ES2196057T3 (es) 2003-12-16
DE69530283D1 (de) 2003-05-15
PT740564E (pt) 2003-08-29

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